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Having SARS-CoV-2 once confers much greater immunity than a vaccine

sciencemag.org

1–10 of 371 posts

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#3
There's really nothing surprising about this conclusion. Before Covid came along and the focus inexplicably shifted to antibodies-only, it was well understood that infection with a pathogen was always likely to result in better immunity than vaccination.

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#4
One can observe how this topic has become political, and is no longer scientific. Our focus and concerns are now all about existing and forthcoming restrictions and mandates for vaccinations and masks -- so much that information like this is no longer even interesting to most people. Not only uninteresting, but vulnerable to censors.

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#5
I can only consider this a positive for those who are vaccine hesitant, as they will probably be getting it, but I can't see how, considering the realistic dangers of a vaccine, a rational individual wouldn't want both forms of protection even if they were previously infected.

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#7
>the risk of developing symptomatic COVID-19 was 27 times higher among the vaccinated, and the risk of hospitalization eight times higher

This sounds convincing, but then in the next graf:

>For instance, the higher hospitalization rate in the 32,000-person analysis was based on just eight hospitalizations in a vaccinated group and one in a previously infected group. And the 13-fold increased risk of infection in the same analysis was based on just 238 infections in the vaccinated population, less than 1.5% of the more than 16,000 people, versus 19 reinfections among a similar number of people who once had SARS-CoV-2.

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#9

I can only consider this a positive for those who are vaccine hesitant, as they will probably be getting it, but I can't see how, considering the realistic dangers of a vaccine, a rational individual wouldn't want both forms of protection even if they were previously infected.

What is the realistic marginal increase in protection from the vaccine for someone who has recovered and is in a very low risk age/comorbidities cohort? Is reducing their absolute risk of a really bad Covid outcome by 0.00001% really worth the risks attendant in the vaccine?

Also, at least one study has hinted that the second dose may reduce humoral immunity.

Re: Having SARS-CoV-2 once confers much greater immunity than a vaccine

#10

>the risk of developing symptomatic COVID-19 was 27 times higher among the vaccinated, and the risk of hospitalization eight times higher This sounds convincing, but then in the next graf: >For instance, the higher hospitalization rate in the 32,000-person analysis was based on just eight hospitalizations in a vaccinated group and one in a previously infected group. And the 13-fold increased risk of infection in the…

Are you saying 32,000 people isn't a large enough study to be meaningful?
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