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Schizophrenia linked to marijuana use disorder is on the rise, study finds

cnn.com

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Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#391

Post by PragmaticPulp »

anxiousanon wrote: post #106
hart_russell wrote: post #7

I think it's too common a sentiment that psychoactive substances like cannabis and psilocybin are harmless and in fact are good for mental health. I've had adverse mental reactions to both and I would caution people with family history of anxiety.

Just as a counter-anecdote. There's depression and anxiety in my family tree, and it has caught up to me too in the last year. Among other remedies, I've experimented with small doses of edibles (they are legal where I live). I don't particularly enjoy the high, but for me it does take the edge off the worst times, without side effects. It lets me at least relax/sleep. (It kind of takes the edge off everything , whic…

This is a touchy subject to discuss on HN, but I’d caution you that much of the scientific literature on the topic of depression and cannabis is not positive. Obviously there is some possibility of bidirectional causation (cannabis worsens depression, depression increases cannabis consumption) but even the most “both sides” papers on the subject still lean toward cannabis worsening depression over time. This paper is a decent “both sides” overview if you can get the full text: https://pubmed.ncbi.nlm.nih.gov/33332004/

Note that the negative effects of cannabis on depression aren’t immediately obvious, as the drug itself makes users temporarily feel better. As such, people tend to associate cannabis with an immediate improvement of symptoms, yet can’t quite pinpoint the long-term downward trend in their depressive symptoms that occurs due to long-term changes of repeated consumption. There is also some concerning evidence to suggest that traditional depression treatments are less effective when someone is consuming cannabis.

One of my good friends is a professional therapist who is very open about her own personal cannabis use. However, she says she spends much of her professional time convincing depression patients to stop consuming cannabis, with positive results for those who can follow through.

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#393

Post by oblib »

SquishyPanda23 wrote: post #386
oblib wrote: post #220

Earlier quoted context omitted.

Yeah, I've heard people say that all my life. Some folks love to believe that. But there's nothing that really backs that up with solid proof. A lot of them whom I've heard say that were coke users, which to me would indicate a lack of intelligence. Here's a couple studies that seem to disprove that myth about weed users but, like all of these studies, they really cannot claim to be conclusive. Still better than most…

The "some folks" include the scientists who actually study this. But good job cherry picking a study. Hope it makes you feel better.

To fair and accurate I cherry picked TWO studies

You didn't cite or include a link to even one. You just tossed a load of bullshit here and hoped it would stick.

By the way... one of those cherry picked links goes to Scientific American's website. Hard to do better than that even if you are picking cherries.

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#394

Post by BTCOG »

GordonS wrote: post #148
bilekas wrote: post #42

Earlier quoted context omitted.

You've hit the nail on the head with my experience. I have noticed this with a brother who smoke daily.. I never really put it down to the marijuana use entirely, but more of an aversion to any kind of confrontation/disagreement that might make him second guess himself etc. Personally I can't smoke it anymore, I get super anxious now and nervous. I don't enjoy it, but I can see why some people who enjoy it would rath…

> Personally I can't smoke it anymore, I get super anxious now and nervous I've heard so many people say the same thing, that they used to enjoy using cannabis, then some years later they find it induces anxiety, jitters and nervousness - I wonder what the mechanism behind this anxiety is? Is it as simple as "modern" cannabis strains having much THC than older ones, or is it something else, possibly age-related, like…

The CB1 receptors actually shrink up and recede with long term use and the effects change with aging. For many long term smokers, this long term heavy use does bring more anxiety. Stronger THC profiles with less CBN, CBG, or CBD in the flower being smoked, coupled with the terpene profiles present in the flower also have widely varying effects. Some smoke a kush strain that is heavy in caryophylene, myrcene, and/or linalool and feel a relaxing effect. For some, couch locking, sedative effects cause more anxiety. While still for others, sometimes lemony strains full of limonene and pinene causes more anxiety but for others the limonene gives one an energetic and uplifting buzz without the anxiety. It's also a psychoactive (THC) and so similar to hallucinogens, for some it's what anxieties are already in the head that amplifies anxiety once high.

Unless you dive deep into the latest chemical/terpene profiles or live in a legal state you may not have heard that much of the type of high actually comes from a compound effect of the terpenes present and level of THC to CBD to CBG to CBN. Every single strain and plant to plant should be thought of as a concoction of sorts.

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#395

Post by runawaybottle »

krustyburger wrote: post #378
runawaybottle wrote: post #70

Earlier quoted context omitted.

Patronization is a strong suit many people (including myself) have nicely ironed at all times in our closet. Nothing is more fun than to put that suit on. The question is, can we tolerate flawed people? Can we laugh about it? Can we let them rant and wear that suit from time to time?

I applaud the creativity, but the phrase “strong suit” originated from bridge and refers to a different kind of suit. I realize I’m probably being patronizing myself by pointing that out. As Bart Simpson once said, “The ironing is delicious.”

Good, you just saved me from sounding like a dumbass in real life.

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#396

Post by bjourne »

watwut wrote: post #329
bjourne wrote: post #315

Earlier quoted context omitted.

I find it disappointing and disheartening that you are dismissing peer-reviewed studies as "propaganda". Your argumentation is not that different from the one used by climate change deniers. The first study is commissioned by the European Monitoring Centre for Drugs and Drug Addiction and the second was funded by a Senior Academic Fellowship from the Society for the Study of Addiction.

Peer reviewed studies disagree and dismiss each other all the time. Peer reviewed studies are often "propaganda". Peer review guarantees certain minimal bar and that your general structure is sane. Reproducibility and actual results are not necessary validated. The larger scientific discussion where study is confirmed is after peer review. On HN, they are specifically disagreed with super often. Especially anything "…

It's sad that science denial is now the norm even on Hacker News.

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#397

Post by slumpt_ »

jefftechentin wrote: post #253
slumpt_ wrote: post #240

Earlier quoted context omitted.

No reason to be wary of recreational use. No more so than you might of caffeine. Not everything is for everyone and that’s 100% ok.

> No reason to be wary of recreational use. No more so than you might of caffeine You should be wary of caffeine use, especially if your culture does not have any rules about its use, or complete enough understanding about its effects. We like drugs because they work, but the problem is we do not know what they do over larger timescales or how to fit them into your life. Weed is a relative newbie in the average Ameri…

People have been using both for thousands of years.

Feel free to be wary. Many of the rest of us will enjoy our lives otherwise without perpetuating unnecessary and by and large scientifically unfounded, culturally-based fears of reasonably innocuous substances.

Beware the “Snoop Dogg pool party” indeed.

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#398

Post by ChrisLomont »

bombadilo wrote: post #219
macksd wrote: post #47

>> In 1995, 2% of schizophrenia diagnoses in the country were associated with cannabis use disorder. In 2000, it increased to around 4%. Since 2010, that figure increased to 8%, the study found. Worded that way, causation isn't the first thing this suggests to me. If percentage of cases associated with marijuana rise, it could also be that a larger percentage of the population is smoking and admitting to smoking mari…

Sorry, but the suggestion that marijuanna use leads to narcissistic personality disorder is absurd.

There is this: "Cannabis use is associated with 2–4 times the likelihood of developing psychosis in healthy individuals:

That sure seems causative.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7255842/

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#399

Post by webinvest »

mullingitover wrote: post #79

I've seen someone have a textbook psychotic break while consuming a lot of cannabis. Radio was sending them secret messages, coworkers were government spies, believed they were Jesus (and normally they'd been a confirmed atheist). As soon as the cannabis consumption stopped, the psychosis stopped. They started smoking again, symptoms came back. I'd also done some googling to try to understand why some people have pan…

It could be a stimulant drug and situational interaction

Re: Schizophrenia linked to marijuana use disorder is on the rise, study finds

#400

Post by thatcat »

eurasiantiger wrote: post #368
heavyset_go wrote: post #299

Earlier quoted context omitted.

People with schizophrenia-related disorders are likely to use substances to deal with the negative symptoms[1] of the disorders. For example, there is a high correlation between having schizophrenia and consuming nicotine[2]: > A strong association between schizophrenia and tobacco smoking has been shown in worldwide studies. Smoking is especially high in those diagnosed with schizophrenia, with estimates ranging fro…

This is meaningless, since it conflates tobacco smoking with pure nicotine. In reality, tobacco smoke contains dozens if not hundreds of different psychoactive chemicals, and certain ones acting as monoamine oxidase inhibitors contribute heavily to tobacco dependence.

Maoi in tobacco smoke is the suspected active ingredient
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