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Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

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Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#111

Post by okaram »

paulryanrogers wrote: post #87
anedcata wrote: post #78

Earlier quoted context omitted.

It used to be common to reply to this sort of fear mongering with "anecdotes aren't data." Cool anecdote, bro. Sorry for that person you, a random internet person I have no reason to trust, allegedly know, who is very, very unlucky. The people in power want us to stay afraid and easy to control. Fauci says vaccines work but doesn't trust them enough to stop going into public with TWO masks! Despite being vaccinated!…

Isn't mask wearing still required after vaccination because of the enforcement costs? I.e. it's too difficult to prove whose been vaccinated in every situation, so by requiring masks until the community reaches the target threshold

Most places don require masks at all. The recommendation (for now) is to keep wearing mask as before.

I assume this will change as/if/when more people become vaccinated.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#112

Post by anoncake »

marcodiego wrote: post #49

For people arguing that not being part of a risk group is a reason not to protect yourself, please take a lesson from brazil. Being part of a 'high risk group' does not saves you from infecting other people who are part of such groups. That's basically what happened in brazil: people who were not part of risk groups crowded, encouraged by the president himself[0][1][2]. The number of infected poeple soared and varian…

So getting vaccinated saves me from infecting the people who have stolen more than a year of my life? I'll pass.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#114

Post by anoncake »

jquery wrote: post #17
psychlops wrote: post #12

The immune system still works as advertised.

What’s the purpose of comments like this? EDIT: I see someone mentioning Trump below and I can’t reply. Trump was never interested in managing covid-19 or effective border control. This would’ve been the perfect opportunity for him to show why having smart borders was useful. He would’ve received support from within the government. He would’ve managed covid-19 successfully perhaps, and won re-election. The problem wa…

That, or "Covid behaves like viruses usually do", describes plenty of headlines of the past 15 months. Remember how everyone was worried that antibody levels drop after an infection? Judging by the media coverage, you'd think memory cells and T cells were a recent, Covid-related discovery. We've known about them since the sixties and they continue to work as advertised.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#115

Post by celrod »

hu3 wrote: post #109
irq11 wrote: post #106

Earlier quoted context omitted.

It is not possible to stop all strains. SARS-CoV2 has multiple zoonotic reservoirs, transmits easily, and persists in the population via asymptomatic infection. We have eradicated one human virus in all of history, and it took a highly effective vaccine and a hundred years. The long tail is very long.

Curious, what virus we eradicated?

Smallpox.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#116

Post by anoncake »

hu3 wrote: post #109
irq11 wrote: post #106

Earlier quoted context omitted.

It is not possible to stop all strains. SARS-CoV2 has multiple zoonotic reservoirs, transmits easily, and persists in the population via asymptomatic infection. We have eradicated one human virus in all of history, and it took a highly effective vaccine and a hundred years. The long tail is very long.

Curious, what virus we eradicated?

Smallpox. Except for some samples in secure laboratories.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#117

Post by evgen »

mrfusion wrote: post #30
jquery wrote: post #13

Earlier quoted context omitted.

For every person that dies (an agonizing death akin to medieval torture), a few more are in intensive care fighting for their lives. For every one of those, others end up in the hospital, spread the disease to others, suffer from “long covid”, or merely suffer greatly. Every person that gets covid adds to the likelihood the disease will become uncontrollable in the long term and endemic. Keep wearing your masks and s…

I don’t see any reason new variants would ever stop coming. What are you proposing is the end point of all of this?

Here is something for you to consider: this is the new 'normal'.

That world you lived in 18 months ago? Gone. Not coming back. There is no 'end point', it just goes on and we learn to adapt. Eventually we get better at it, learn more about what is and is not a risk, and a few things start to look like the 2019, but most things don't go back.

This is the reality you need to adjust to.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#118

Post by lamontcg »

Tagbert wrote: post #76
marcodiego wrote: post #49

For people arguing that not being part of a risk group is a reason not to protect yourself, please take a lesson from brazil. Being part of a 'high risk group' does not saves you from infecting other people who are part of such groups. That's basically what happened in brazil: people who were not part of risk groups crowded, encouraged by the president himself[0][1][2]. The number of infected poeple soared and varian…

I am hearing from friends and family in Brasil that the Brasilian variant is more severe among younger victims than the original COVID version. There is an increase of deaths among twenty-year-olds as a result.

The second wave of the 1918 pandemic was also more deadly to younger people.

Various theories have been offered as to why, none of which are proven, including that it may have been observational errors or due to overcrowding conditions due to the war and viral dose.

I wonder if it isn't due to the virus coming under pressure due to a large chunk of the population becoming immune, so evolution favors higher transmissibility. And the easy knob the virus has to increase transmissibility is to increase viral load, which has the side effect of increasing virulence/lethality. That is consistent with that fairly well studied mechanism of parasites/viruses, along with being consistent with what we're observing.

At any rate considerations like that are why I'm not letting my guard down until I'm vaccinated and why it seems stupid to do so.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#119

Post by timr »

legulere wrote: post #47
ed25519FUUU wrote: post #9

Earlier quoted context omitted.

Some more: > Indiana's IFR for noninstitutionalized persons older than 60 years is just below 2% (1 in 50). In comparison, the ratio is approximately 2.5 times greater than the estimated IFR for seasonal influenza, 0.8% (1 in 125), among those aged 65 years and older (5).

That is just one factor though in which COVID-19 is worse than the seasonal influenza though. COVID-19 has a basic reproduction number of 3.3 – 5.7, while the seasonal influenza has one of 0.9 – 2.1 [1], which means that it spreads far more easily. You cannot just wait until summer for influenza season to be over. With influenza you have a higher rate of existing immunity in the population. With COVID-19 it is basica…

"Younger people are also more affected [2]"

The paper you're citing says "younger" means 59, vs 66 for influenza:

> Patients with COVID-19 were younger (median age [IQR], 59 [45–71] vs 66 [52–77]; P Also, this is data from a single hospital, across two different years. The overall trends for SARS-CoV2 are not even remotely debatable: the risk of mortality rises exponentially with age. It's one of the most striking features of the virus. To claim, based on this one paper, that "younger people are more affected" is to miss the forest for the trees.

"In the end you cannot compare a pandemic situation to influenza season."

You absolutely can, and in fact, you're doing it. What you're trying to say is that Covid is somehow unilaterally much worse than influenza, but that isn't true. It's much worse for the elderly (>65), but for most other age groups, it's about the same, if not a little bit better. You have to squint and split hairs and pick sources selectively to start making strong claims of increased severity in age groups under ~50, and it's simply not a believable claim for people under the age of ~30.

The disease can be bad without exaggerating its threat.

Re: Neutralizing antibodies against SARS-CoV-2 variants after infection, vaccination

#120

Post by [deleted] »

mherrmann wrote: post #62
marcodiego wrote: post #49

For people arguing that not being part of a risk group is a reason not to protect yourself, please take a lesson from brazil. Being part of a 'high risk group' does not saves you from infecting other people who are part of such groups. That's basically what happened in brazil: people who were not part of risk groups crowded, encouraged by the president himself[0][1][2]. The number of infected poeple soared and varian…

Also for selfish reasons. I know a 24 year old ballerina (so a professional athlete) who had it two months ago and is now at 80% lung capacity.

[deleted]
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