141–150 of 236 posts
[1] https://en.wikipedia.org/wiki/2018_Nipah_virus_outbreak_in_K...
Really good news! Hopefully these get approved relatively quickly. I'm most excited about the seasonal flu vaccine. That could be a major game changer.
I can't understand people who wants to get vaccinated yearly for just a flu. Please make me understand. I mean it's just a flu and we have Netflix. As a Moderna shareholder I think that is stupid. As a healthy eater I think that is really stupid. Now I can only think I must be really stupid.
Damn can you imagine? I never imagined that an HIV vaccine would be possible within my lifetime. Kind of reminds me of HepC. An older coworker told me how a friend killed himself back in the day for getting HepC from tainted blood (pretty much a death sentence at that time and it consumed him). But now it’s possible to CURE it and hopefully it’ll be the same for HIV soon. Fuck, science like this is amazing.
Just to be clear, a vaccine doesn't cure a disease. It prevents one from contracting it.
In the case of HIV, the problem is not that the body is unable to properly respond to the disease, the initial infection is usually benign and the immune system produce the antibodies necessary to fight it, that's what being HIV+ means.
Problem is, HIV mutates so quickly that the immune system is essentially playing whack-a-mole and cannot eradicate the virus completely.
A vaccine that imitates a real infection perfectly is mostly useless, because it will train the immune system on the wrong mutation.
The trick here is to focus the immune response on parts of the virus that don't change, by using mRNA that only produce these parts.
It is like telling the body what the weak point of the virus is. It is useful both before and during the attack.
Very cool! Also I’d hope to see Lyme in the mix. It’s so pervasive and creates all kinds of weird dietary and nervous system issues.
>It’s so pervasive and creates all kinds of weird dietary and nervous system issues. I am not an expert, but I think it would be amiss to omit the Lyme disease controversy with these statements. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477530/ Lyme disease has a simple antibiotic treatment. The Lyme serology test has high false-positive rate. There might be many people who believe they have Lyme disease therefor…
This is common in north eastern state rural areas and has been getting steadily worse.
We are constantly doing tick checks on the kids after one of our friends related that she suffered lifelong issues after being bitten by a tick 40 years ago in our neighborhood.
A vaccine would be a huge relief.
Very cool! Also I’d hope to see Lyme in the mix. It’s so pervasive and creates all kinds of weird dietary and nervous system issues.
We already have a Lyme disease vaccine. However, the manufacturer refuses to sell it for human use due to PR threats from conspiracy theorists. Unfortunately, creating vaccines is only half the battle. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870557/
> First, the vaccine efficacy of The real underlying malicious behavior here was from the lawyers who actively recruited and fomented anti-vax culture...
> The final agreement included over 1 million dollars in legal fees for the prosecuting lawyers, but provided no financial compensation to the ‘vaccine victims’.
Earlier quoted context omitted.
There is no way to eliminate these doubts. If you made a magical cure that totally eliminated the bacteria that causes Lyme disease, then these patients would take it, and it would almost certainly not work (because "chronic Lyme" isn't a real syndrome, and these patients don't have this bacteria). However, that would not convince them, they'd just claim that the medical establishment has failed them yet again (or wo…
People are not making up illness for the fun of it. Their ailments are very real and they have a cause. Malingering exists, but the profile of the chronic Lyme patients you speak about is not at all the one of persons in need of being nursed by the society like babies... Just imagine you go to the doctor and all you say is dismissed because he thinks you make it up? What a despair you would be in! Speaking of a close…
I have absolutely no doubt that their problems are real. I fully believe that these patients are honest and that they really suffer, and they need treatment. I do not believe at all that they are "making it up".
But they don't suffer from "chronic Lyme".
There's just no evidence that it's a real thing. But just like with electromagnetic hypersensitivity, Morgellon's disease, "Wind Turbine syndrome", or any of a legion of "diseases" from medical history, you can't treat them medically if there's no evidence they exist. It would be malpractice for doctors to prescribe real drugs for fictitious syndromes, and it wouldn't do anything to convince their patients either.
Earlier quoted context omitted.
Some more detail in this article from July, they’re using mRNA to make the body produce virus like particles https://www.aidsmap.com/news/jul-2020/novel-vaccine-induces-...
Any effective HIV vaccine would presumably cause false-positives to the HIV antibody tests. Recently an Australian COVID-19 vaccine candidate trial was halted due to participants developing antibodies to proteins in the vaccine that were taken from HIV genome, causing false-positive on a HIV test. [1] Such false-positives could easily be co-opted by anti-vaxxers especially in light of the the famous Soviet Union disi…
I'm less interested in how anti-vaxxers think, than the fact that the HIV test will need to re-target a different protein.
Earlier quoted context omitted.
Just to be clear, a vaccine doesn't cure a disease. It prevents one from contracting it.
Some vaccines are also cures. In the case of HIV, the problem is not that the body is unable to properly respond to the disease, the initial infection is usually benign and the immune system produce the antibodies necessary to fight it, that's what being HIV+ means. Problem is, HIV mutates so quickly that the immune system is essentially playing whack-a-mole and cannot eradicate the virus completely. A vaccine that i…
Earlier quoted context omitted.
People are not making up illness for the fun of it. Their ailments are very real and they have a cause. Malingering exists, but the profile of the chronic Lyme patients you speak about is not at all the one of persons in need of being nursed by the society like babies... Just imagine you go to the doctor and all you say is dismissed because he thinks you make it up? What a despair you would be in! Speaking of a close…
> People are not making up illness for the fun of it. Their ailments are very real and they have a cause. I have absolutely no doubt that their problems are real. I fully believe that these patients are honest and that they really suffer, and they need treatment. I do not believe at all that they are "making it up". But they don't suffer from "chronic Lyme". There's just no evidence that it's a real thing. But just l…
If these patients get a diagnostic, even if it is not Lyme, I am sure that would help them very much.
It is true that the medicine is more than often not yet capable of giving satisfying diagnostics, and that misdiagnostic is counterproductive...
However I remember I saw some sound studies on biofilm protein immunity that was triggering autoimmune disorder, in relation to the borreliosis. This is why I had this strong opinion. I will report here if I manage to retrieve the exact reference.
One of these is for the little known Nipah virus. This virus is really scary. Like the Coronavirus, it jumps to humans from bats. Unlike the Coronavirus, it is extremely lethal. In the last outbreak, in 2018 [1], the case fatality rate was 89%. Fortunately, there were only 19 cases (17 died). [1] https://en.wikipedia.org/wiki/2018_Nipah_virus_outbreak_in_K...
I just submitted about this:
* https://www.bbc.com/future/article/20210106-nipah-virus-how-...