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Moderna is announcing three new vaccine programs

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Re: Moderna is announcing three new vaccine programs

#2
Didn't Moderna already announce the seasonal flu vaccine programs on the research presentation day?

Anyways, I really hope them to succeed, my mother didn't take the flu vaccine ,,because it's risky and not that useful anyways''.

Moderna can make it much more efficient with less side effects, so I'm looking forward to it.

Re: Moderna is announcing three new vaccine programs

#4
(Caveat: amateur opinion based on mainstream broad understanding, not an actual scientist.)

This is interesting, but so far a weak first step on flu. Each year experts stare at numbers and perhaps read some tea leaves to choose 4 strains to cover, often missing somewhat.

The innovation I'd like to see: ignore the "choose 4" process, and instead aim to cover all known strains.

Re: Moderna is announcing three new vaccine programs

#5
post #2

Didn't Moderna already announce the seasonal flu vaccine programs on the research presentation day? Anyways, I really hope them to succeed, my mother didn't take the flu vaccine ,,because it's risky and not that useful anyways''. Moderna can make it much more efficient with less side effects, so I'm looking forward to it.

Vaccines are interesting, but I'm much more intrigued by what this may mean for future therapeutics if their methods work well moving forward.

Re: Moderna is announcing three new vaccine programs

#6

(Caveat: amateur opinion based on mainstream broad understanding, not an actual scientist.) This is interesting, but so far a weak first step on flu. Each year experts stare at numbers and perhaps read some tea leaves to choose 4 strains to cover, often missing somewhat. The innovation I'd like to see: ignore the "choose 4" process, and instead aim to cover all known strains.

https://www.sciencemag.org/news/2020/12/innovative-universal... (“Innovative universal flu vaccine shows promise in first clinical test”)

https://www.nature.com/articles/s41591-020-1118-7 (“A chimeric hemagglutinin-based universal influenza virus vaccine approach induces broad and long-lasting immunity in a randomized, placebo-controlled phase I trial”)

Re: Moderna is announcing three new vaccine programs

#7

(Caveat: amateur opinion based on mainstream broad understanding, not an actual scientist.) This is interesting, but so far a weak first step on flu. Each year experts stare at numbers and perhaps read some tea leaves to choose 4 strains to cover, often missing somewhat. The innovation I'd like to see: ignore the "choose 4" process, and instead aim to cover all known strains.

Moderna has a much more flexible production process so should be more resistant to misses.

Re: Moderna is announcing three new vaccine programs

#9

(Caveat: amateur opinion based on mainstream broad understanding, not an actual scientist.) This is interesting, but so far a weak first step on flu. Each year experts stare at numbers and perhaps read some tea leaves to choose 4 strains to cover, often missing somewhat. The innovation I'd like to see: ignore the "choose 4" process, and instead aim to cover all known strains.

>amateur opinion based on mainstream broad understanding

I don’t think experts are reading tea leaves and it’s pretty wild to claim that. There are literally billions of dollars at stake. To bring it bag to software, that’s like me claiming I think machine learning people are just using fancy excel formulas.

Re: Moderna is announcing three new vaccine programs

#10
post #3

Really good news! Hopefully these get approved relatively quickly. I'm most excited about the seasonal flu vaccine. That could be a major game changer.

Yeah I agree - so much of the original downlplaying of Covid was along the lines of "Well, the flu kills 50,000 people per year and we don't take extraordinary measures" which is an insane line of thought for multiple reasons but not least because we just write off 50,000+ people per year without much of a stink.
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