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Moderna is announcing three new vaccine programs

investors.modernatx.com

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Re: Moderna is announcing three new vaccine programs

#81

Post by ed25519FUUU »

danfo wrote: post #78
throwarayes wrote: post #8

Very cool! Also I’d hope to see Lyme in the mix. It’s so pervasive and creates all kinds of weird dietary and nervous system issues.

>It’s so pervasive and creates all kinds of weird dietary and nervous system issues. I am not an expert, but I think it would be amiss to omit the Lyme disease controversy with these statements. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4477530/ Lyme disease has a simple antibiotic treatment. The Lyme serology test has high false-positive rate. There might be many people who believe they have Lyme disease therefor…

I still think it’s worth. The amount of life lost to people with chronic Lyme is significant, even if the number of infected is low.

Re: Moderna is announcing three new vaccine programs

#82

Post by vmception »

mikeyouse wrote: post #10
cogman10 wrote: post #3

Really good news! Hopefully these get approved relatively quickly. I'm most excited about the seasonal flu vaccine. That could be a major game changer.

Yeah I agree - so much of the original downlplaying of Covid was along the lines of "Well, the flu kills 50,000 people per year and we don't take extraordinary measures" which is an insane line of thought for multiple reasons but not least because we just write off 50,000+ people per year without much of a stink.

Now its moved to “but lockdowns have been going on so long that this is just normal deaths from everything else” and “thats not a covid death!” Not realizing that the flu also has those same counting errors or overlapping causes, leading everyone to begin clarifying “complications related to COVID-19”

“Fortunately” we get to see how much further their mental gymnastics will go as the death count will begin greatly exceeding all other causes over the next 3 months!

Any guesses?

“It was a tough winter for people that already were stressed!”

Re: Moderna is announcing three new vaccine programs

#83

Post by Debug_Overload »

someperson wrote: post #58
m-ee wrote: post #48

Earlier quoted context omitted.

Some more detail in this article from July, they’re using mRNA to make the body produce virus like particles https://www.aidsmap.com/news/jul-2020/novel-vaccine-induces-...

Any effective HIV vaccine would presumably cause false-positives to the HIV antibody tests. Recently an Australian COVID-19 vaccine candidate trial was halted due to participants developing antibodies to proteins in the vaccine that were taken from HIV genome, causing false-positive on a HIV test. [1] Such false-positives could easily be co-opted by anti-vaxxers especially in light of the the famous Soviet Union disi…

Taking into account anything conspiracy nutjobs have to say about this stuff is an exercise in futility. They will not not find another wild excuse to declare conspiracy.

Re: Moderna is announcing three new vaccine programs

#84

Post by lysp »

onlyrealcuzzo wrote: post #59
hooloovoo_zoo wrote: post #19

Would it be easier to cover more flu strains with an mRNA vaccine? Could we shove like 100 in there?

Also, can we get a vaccine for most of the common colds??

Found this:

https://www.verywellhealth.com/why-there-will-never-be-a-vac...

> Vaccines target a specific virus or pathogen. One difficulty with developing a vaccine for the common cold is there are at least 200 different viruses that can cause cold symptoms, including rhinovirus, coronavirus, adenoviruses, and parainfluenza.1

> Rhinovirus makes up about 75% of colds. Still, there are more than 150 strains of it circulating at the same time.

> At this time, there is currently no way for one vaccine to protect against all possible strains that can cause the common cold.

It also goes on to say it self-resolves and only causes mild illness.

So they potentially could find a vaccine that covers most, but I'm guessing would be a waste of resources.

Re: Moderna is announcing three new vaccine programs

#85

Post by Bellamy »

cogman10 wrote: post #3

Really good news! Hopefully these get approved relatively quickly. I'm most excited about the seasonal flu vaccine. That could be a major game changer.

I can't understand people who wants to get vaccinated yearly for just a flu. Please make me understand. I mean it's just a flu and we have Netflix.

As a Moderna shareholder I think that is stupid. As a healthy eater I think that is really stupid. Now I can only think I must be really stupid.

Re: Moderna is announcing three new vaccine programs

#86

Post by hirsin »

Bellamy wrote: post #85
cogman10 wrote: post #3

Really good news! Hopefully these get approved relatively quickly. I'm most excited about the seasonal flu vaccine. That could be a major game changer.

I can't understand people who wants to get vaccinated yearly for just a flu. Please make me understand. I mean it's just a flu and we have Netflix. As a Moderna shareholder I think that is stupid. As a healthy eater I think that is really stupid. Now I can only think I must be really stupid.

Because it's really simple to do? It sucks to be sick, and there's a usually free, probably effective means of avoiding it. Plus, if you're around people for whom it's not "just" the flu it helps protect them.

Re: Moderna is announcing three new vaccine programs

#87

Post by throwaway13337 »

cycrutchfield wrote: post #12
elil17 wrote: post #11

Earlier quoted context omitted.

We already have a Lyme disease vaccine. However, the manufacturer refuses to sell it for human use due to PR threats from conspiracy theorists. Unfortunately, creating vaccines is only half the battle. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2870557/

It's very odd that dogs can get vaccinated for Lyme but not humans...

Agreed.

I wonder about the trolley problem that is medical testing requirements.

It seems like we, as a society, would tend to never want to pull the lever to save more at the cost of risking a few. Social and contractual liability makes it a bad trade.

Acceptable risk is very low which can, paradoxically, cause more death and discomfort.

It would be nice to see a greater awareness of the tradeoffs. These things tend to get emotional, though, so not much gets done.

https://en.wikipedia.org/wiki/Trolley_problem

Re: Moderna is announcing three new vaccine programs

#88

Post by scoopertrooper »

Guthur wrote: post #63
someperson wrote: post #58

Earlier quoted context omitted.

Any effective HIV vaccine would presumably cause false-positives to the HIV antibody tests. Recently an Australian COVID-19 vaccine candidate trial was halted due to participants developing antibodies to proteins in the vaccine that were taken from HIV genome, causing false-positive on a HIV test. [1] Such false-positives could easily be co-opted by anti-vaxxers especially in light of the the famous Soviet Union disi…

And could you blame people for being paranoid when the CIA have used vaccine programs for various purposes in the past. Though they've apparently now stopped.

I assume you are referring to the time the CIA co-opted an immunisation programme as part of the hunt for Bin Laden.

I don't think anyone has ever seriously suggested that the CIA has tampered with the vaccines. They merely co-opted the inoculation process in order to gain a biological sample.

Re: Moderna is announcing three new vaccine programs

#89

Post by rtpg »

throwaway13337 wrote: post #87
cycrutchfield wrote: post #12

Earlier quoted context omitted.

It's very odd that dogs can get vaccinated for Lyme but not humans...

Agreed. I wonder about the trolley problem that is medical testing requirements. It seems like we, as a society, would tend to never want to pull the lever to save more at the cost of risking a few. Social and contractual liability makes it a bad trade. Acceptable risk is very low which can, paradoxically, cause more death and discomfort. It would be nice to see a greater awareness of the tradeoffs. These things tend…

You can't make trolley problem tradeoffs when there's enough uncertainty involved in all the steps.

Older medicine is filled with supposed cures to issues that cause issues down the road. We also have countless medical trials that show no positive effects on the disease it's trying to cure, and outright ill effects (both short term and long term).

If we _did_ have visibility and a good understanding of the effects of stuff, you would think that Covid, of all things, would push at least some people more down this argument you are making.

But basically everyone involved (including many many people who had extreme incentives to push a vaccine through) stuck to the trial discussions.

I do understand the "Extenuating circumstances" argument. But this sort of massive generality reeks of Dunning-Krueger.

Re: Moderna is announcing three new vaccine programs

#90

Post by choeger »

CryptoPunk wrote: post #66
syntaxing wrote: post #31

Damn can you imagine? I never imagined that an HIV vaccine would be possible within my lifetime. Kind of reminds me of HepC. An older coworker told me how a friend killed himself back in the day for getting HepC from tainted blood (pretty much a death sentence at that time and it consumed him). But now it’s possible to CURE it and hopefully it’ll be the same for HIV soon. Fuck, science like this is amazing.

Just to be clear, a vaccine doesn't cure a disease. It prevents one from contracting it.

In case of HIV, though, it may also (partially) replace medication, considering that the virus is hiding from the immune system for a while.
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