481–490 of 1001 posts
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The markets? Spare me. What are the markets, a handful of rich in banks and large corporations? They are neither wise nor competent, why should every news story be suffixed by how "the markets" (swt) react?
Since you asked, also the pension funds of almost everyone you know.
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+ ~90% of individuals achieve immunity It could also refer to 90% reduced severity. A 60% vaccine can reduce the severity of the illness by 40% so only 40% of the expected number end up in hospital.
The first line of the article states: "The first effective coronavirus vaccine can prevent more than 90% of people from getting Covid-19, a preliminary analysis shows."
https://www.cdc.gov/flu/prevent/misconceptions.htm
and this
https://www.cdc.gov/flu/prevent/vaccine-benefits.htm
you'll see that that's not how it always works.
> Flu vaccination can reduce the risk of flu-associated hospitalization for children, working age adults, and older adults.
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I think we can eradicate it by contact tracing. With 90% efficiency it will be extremely tough for the virus to spread. For any new cases you simply test everyone in the vicinity of the infected person. But I don't think even that will be necessary. 90% efficiency reduces R so much, it will probably die out on its own. The real problem is mutations that are not covered by the vaccine. If it mutates as efficiently as…
Yup. But we do need the government to step in and do this (contact tracing etc.). Hopefully, with the new administration...
My belief is that contact tracing is a cultural non-starter here. There are people who protest with large, semi-automatic rifles because they don't want to wear masks inside private businesses.
There's absolutely no way they're going to trust a contact-tracing process championed by the government, even if there's no way for the government to access the data.
I suspect much of the population will continue to ignore the virus and winter weather will cause a spike that will cripple hospitals.
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The Ebola vaccine required -80 C storage as well and they got it into literal war zones. It’s a difficult problem, but a solved one.
Ebola was localized. COVID-19 is not. I like your optimism, and what you said isn't incorrect about Ebola at the time, but I don't think it's correct about our current situation. How many locations globally have this level of refrigeration? Given that there would be high demand for it, wouldn't prices on any available refrigerators exceed what even the most altruistic companies and organizations could pay? This still…
* The largest chilled supply chains, for things like frozen food, don't get anywhere near -80°C
* The question of what to do in poor countries is very much unsolved
On the other hand:
* Developed countries have at least some cryogenic supply chain in place, for things like fertility medicine.
* You can get a surprisingly long way with couriers transporting insulated boxes full of dry ice (or liquid nitrogen).
* The prize on offer here is absolutely huge, because lockdown is so expensive. $10 billion a day buys a heck of a lot of couriers.
I'm currently recovering from Covid-19 and hopefully won't need it, however this line sounds a bit strange: "It uses a completely experimental approach - that involves injecting part of the virus's genetic code - in order to train the immune system." I did my flu (not Covid) vaccine shot about 3 weeks ago, just before catching the nastier one, and according to the doctors it works exactly that way, although this one…
What they mean is that instead of injecting viral proteins or deactivated virus (as in a flu vaccine), they are injecting mRNA which causes your own cells to make a section of viral protein, which then triggers a strong immune response. This COVID vaccine will be the first major mRNA vaccine. https://jamanetwork.com/journals/jama/fullarticle/2770485
I'm fine with this vaccine being available for people who want it, but as someone who is low risk, I really hope this doesn't become mandatory. A lot of people aren't old enough to remember the Swine Flu vaccine and all the complications from that.
No one is talking about the safety here and that's disturbing. I don't see how a vaccine can be listed as safe with less than a year of testing. Traditionally it's an 8~12 year process.
A friend of mine (who is a nutjob), said a few months ago that even if the vaccine doesn't work, they can say it would work 80-90%, because that's the amount of people who don't show symptoms anyway. I don't know anything about this, but now it happened in a way he said, so what do professional here think about this?
So no, they can't do what you described.
Good: + ~90% of individuals achieve immunity. + no significant side-effects. Not so good: - two doses needed, 3 weeks apart, immunity after one month from first dose. Slow rollout. - -80C storage and transport needed. Challenging, but doable in developed countries, but still may slow down mass rollout. Not feasible in many developing countries. I still wonder about long-term immunity. Anyone can share any insight?
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I would assume that the countries are the only ones with a factory that is capable of making this. Give me a few billion dollars and a year and I can set up another factory, but it would have been too risky an investment 1 year ago (before COVID), or even 3 months ago . Even now it is too risky an investment as the current factories can produce a lot of vaccine, and there are other candidates that also have factories…
Didn't Bill Gates' foundation invest 6-7 billion dollars in manufactoring capabilities for vaccines this spring?
Great news and the markets are reacting very positively to the news as well which indicates to me this could be the beginning of the end!
Yeah, setting aside all the politics and silliness, the science going on around this pandemic is remarkable. Going from nearly zero (yes, there was a bunch of research from SARS-Cov-1, MERS, and similar to build off of but nothing like this) to a functioning, tested, and mass manufactured vaccine in a year is absolutely jaw dropping. Even if it takes two years to distribute widely, three years to stomp out a pandemic…