Live data from Hacker News

Intermittent fasting from dawn to sunset induces anticancer response

pubmed.ncbi.nlm.nih.gov

81–90 of 388 posts

Re: Intermittent fasting from dawn to sunset induces anticancer response

#81
post #73

Earlier quoted context omitted.

As someone who absolutely needed sugar in coffee before I considered it drinkable, I can tell you that you can wean yourself off it. It took me several months before I stopped noticing its absence but nowadays I don’t miss it. I still use milk though!

I'm with you there, milk alone is almost too sweet for me because I rarely add sugar to anything. But I think I need it for the creaminess (fat?) to cut the bitterness (and adding oil/butter is probably worse).

the fat is very useful in the palatability of coffee. a little coconut butter does the trick, and is also aligned with a low calorie intake

Re: Intermittent fasting from dawn to sunset induces anticancer response

#82
post #12

Earlier quoted context omitted.

The duration in the article is 4 months. The real issue is small sample size. (14 people)

That's a really small sample size. Are they allowed to publish a study like this for such a small sample? Does anyone know if there is a minimum threshold size?

Allowed to publish? First it's a pilot study. Second, it's actually not a small sample size if you reasonably anticipate big effects and have multiple measures for each of the people at multiple time points. It isn't an observational study, though believers might have wished for a matched control group - - the anticancer effects might have come from the Ramadan prayer vs fasting!

Re: Intermittent fasting from dawn to sunset induces anticancer response

#83
post #34

The "research" is politically motivated, it is thus garbage. Especially considering that it would be dangerous to publish the result if it were to show the other way, not that they would want to publish it. Besides, not having even a drop of water for longer than 12 hours during summer is dangerous, not only to fasting people themselves but to the society as a whole since they drive cars and they have higher rate of…

This is published in Nature, which does not traffic in garbage. This is an observational (not experimental) study which means that the subjects already planned to fast in observance of Ramadan, and the paper discussed what was observed wrt to health and cancer indicators. It's not a polemic.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#84
I've tried various IF protocols, particularly a four hour feeding window, and have mostly struggled with it. I've just gotten hungry early or late, and after a few weeks succumbed. Or I find myself going to bed way early to evade my hunger. IF hasn't been impossible for me, but difficult.

And then suddenly, it's easy, natural. Now I eat just once or twice a day without intending to. It would be an effort to eat more. The difference for me is a carnivore diet, mostly beef. It's just far more satiating than anything else I've tried and I've done most things from raw veganism to this.

I do believe that when I eat matters, but what I eat makes a big difference to when.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#86
post #79

Earlier quoted context omitted.

Yeah, this is why I prefer one mead a day (OMAD). It's a very large meal, 1600-2000 calories over a 2 hour period but I find it much easier to control my calorie intake this way. The only thing I regret since the pandemic is drinking coffee. I try to limit the amount of sugar and almond milk I add, but I feel like it's impacting my diet some how.

Black coffee all the way my friend! I know it's easier said than done. I resisted for a long time, but finally took the plunge ;-) when doing a fasting diet that allowed only water and black coffee outside the eating window. Now it's stuck.

In hindsight, I think one of the smartest decisions I made for myself was to first try coffee black. Since I didn't know any better, it was extremely easy to commit to it, and I am appreciative of it today. I wish I could influence more people to do it at their age, because I think a lot of people would appreciate it when they're older.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#88
post #52

Earlier quoted context omitted.

I’ve been looking for a good source but haven’t found one. Has it not been studied in humans yet?

I think I heard it on the FoundMyFitness podcast which has excellent discussions about fasting science. I think it may have been the last interview with Valter Longo. I’ll see if I can dig it up, but their website would be a good starting point.

"Someone said so in an interview" isn't really compelling evidence. Do you know of actual evidence of this? Studies?

Re: Intermittent fasting from dawn to sunset induces anticancer response

#89

Anecdata: I have followed IF with a 1100 calorie deficit per day by only eating 1200 calories at dinner for 3 months. This translated to more than 1kg weight loss per week, pretty reliably. Overall I lost 17kg. I adjusted the TDEE and calorie values as needed to maintain the weight loss speed. The weight loss was extremely fast, but so was the rate at which I lost lean mass. This makes sense, as I didn't exercise muc…

Few things:

1100 calorie deficit is a bit extreme. Shoot for 500, or maybe 750 if you are pretty heavy.

How much protein did you eat? You'll maintain more muscle if you eat more protein.. consider 50% of calories from protein. Lifting weights also helps with maintaining lean muscle mass.

Alcohol can mess a lot with fluid retention. A good strategy for that when measuring progress is to weigh yourself each day but only look at the average weight over two weeks to see if you are progressing in the right direction.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#90
post #29
post #23

Earlier quoted context omitted.

We’re working on this. Harder than it seems.

By "we", you mean https://zerofasting.com/ ? Seems like a nice app!

I tried that app a very long time ago, and then in an update they forced users to create an online account with no local use option. I promptly removed it since I’m averse to creating online accounts when I see no good reason to do it.
Post reply on HN