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Vaccine hopes rise as Oxford jab prompts immune response among old and young

reuters.com

651–660 of 712 posts

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#651

Earlier quoted context omitted.

i haven't read through all the questions asked here, but yours is perhaps the least stupid i suspect you may already know the answer to your question; of course not everyone needs to be vaccinated - that's the job of any reasonably healthy immune system and this virus, which has not been properly isolated by the way, and that comes directly from the CDC, is not particularly dangerous, and that comes directly from the…

> this "pandemic", which by definition is not a pandemic > any thinking human being knows that masks are, at best, largely ineffective at preventing transmission, as is "social distancing" > it becomes very questionable whether there even is a "novel" corona virus or whether it's the flu You know, I live in Adelaide, where we haven't had a single locally-acquired case in several months. I've been wondering how almost…

As someone living in Melbourne it's been frustrating to see this same nonsense spread locally by a very vocal minority, followed by "lockdowns don't work".

I'm celebrating that following the science here has taken us from > 700 new cases per day, to our second consecutive day of zero (and lockdown ending less than 3 hours from now)

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#652

Earlier quoted context omitted.

The US, as a union or the states individually, generally does not mandate child immunizations. Many states make them (usually with fairly broad exemptions, often including belief-based) requirements for public schools, though.

They should mandate it across the board with only exceptions based in medical science.

German Democratic Republic did this, with a resulting 99% vaccination rate.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#653

This is only one of 11 vaccines now in phase III efficacy tests.[1] Six vaccines already have "partial approval", but those are the ones in Russia and China, which may or may not be working, and the governments decided to try anyway. All of those provoke an immune response. Whether it's enough of the right immune response is found out in phase III testing. Something is probably going to work. The big question is how…

Not happening, recent polls suggest that in Germany, 55% percent of the population is willing to get the vaccine. That isn't enough for herd immunity (at around 60%) and real vaccination rate will be even lower. There is also no chance in hell that Germans will allow a government-mandated vaccine. It's unconstitutional and there is heavy opposition to government-mandated anything throughout all of society. So we will…

It seems likely that percentage will increase as more people are vaccinated and do not have adverse side effects, so people gain trust in the vaccine.

The same is true for other vaccines. See for example [the figure on this page](https://www.gavi.org/vaccineswork/qa-ola-rosling-gapminder): in this survey, in Germany, 13% said they believe vaccines are not safe in general, but only 3% of babies are not getting the measles vaccination.

So let's hope many of the people that currently are not planning to get the vaccine, will change their mind and actually do so in the end. I think good information campaigns in the media and testimonies of friends that have received the vaccine will do a lot to mitigate this problem.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#654
post #436

Earlier quoted context omitted.

What you’re describing as “reckless behavior” is just normal behavior in a non-covid world. If vaccine candidates are social distancing, wearing masks, and staying home how will the researchers get the data they need? If you are following “covid best practices” it is extremely unlikely that you will contract covid. Would the researchers not want people to go out and live their normal lives?

The point is if the two groups behave differently wrt risk then the trial is probably ruined. Maybe you're assuming the vaccine will be 100% effective; experts I've heard are saying to expect something like the flu shot.

Experts need to control to control expections. The flu shot like 50% effenceny is a possibility, and we know anti vaxxers latch onto that with confused statistics. The flu shot is poorly effective because the flu mutates though, covid is more stable so odds are that the vaccine will be more effective, but we are still playing odds of something we don't know, so it is best to assume the worse.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#655

Earlier quoted context omitted.

> in particular, but not limited to, the brain Judging from our response to Covid-19, if this had actually been the collectively-feared zombie virus, the pandemic would have been far worse than any fictional account has manage to capture so far.

How so? World War Z Walking Dead Shawn of the Dead * 28 Days Later The Last of Us What's worse than the above? * (ok maybe not this one)

We are headed towards: Hunger Games, Children of Men, Demolition Man, Judge Dredd, Escape from NY/LA

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#656
post #605

Earlier quoted context omitted.

It's rudimentary to figure out if you got a vaccine or placebo. Live vaccines tend to produce the type of temporary localized soreness you experience with a flue shot. Placebos do not. Really it's about measuring how likely vaccinated participants are to contracting the virus than those that received the placebo.

The placebo is the meningitis vaccine. A real vaccine, with side effects that are similar to what is expected of the covid-19 vaccine. It is a well tested and safe vaccine and it will protect you from meningitis but not from covid-19. They are doing that exactly for the reason you are mentioning. Of course, participants are aware of the nature of the placebo they might receive.

> The placebo is the meningitis vaccine

wtf?! a placebo should by definition have no effect at all

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#657

Earlier quoted context omitted.

Did you experience temporary soreness near the location of the shot? Generalized tiredness, etc, that you might associate with a flu shot? How often are your follow-ups?

Yes. I had generalized pain in both arms after the first injection. Not the second. Nothing worse than you'd expect from another vaccination. Mild fever for 48 hours that meant I was too tired to exercise, but I was more than fine to work. (I'm a software engineer. I think if I had a more manual job, I would've struggled!) My follow-ups are every 2 months at a local hospital. They take general observations, ask about…

Do you know if the placebo is laced with something to simulate those side effects? Or is that a clue that you got the real thing? Also I'd assume the vaccine would make you test positive for the immunological screening tests?

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#658

I'm in the trial. It's really exciting, not least because form a purely selfish point of view, I might be immune already! ...or not. But it's exciting either way! AMA?

>AMA? Have you experienced any side effects, even mild like injection pain or fatigue? I'm in the Moderna study and feel pretty disappointed that I may have gotten the placebo.

Did they disclose what the control group got as a placebo? For instance, in this study it's a meningitis vaccine, so it could still have those side-effects if you've never had that vaccine.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#659
post #30

Earlier quoted context omitted.

Given that immunity from infection is currently questionable your suggestion doesn't make sense. The reason the findings mentioned in this article are important is because the immune response seems to be stronger than that seen in people that have been infected and recovered. So this vaccine would be better at creating herd immunity than just allowing everyone to get infected. At the same time vaccinations will have…

How is immunity from infection questionable? We had 43 million cases and about a dozen or so reinfections. Not sure if confirmed reinfections reach the double digits yet.

https://www.bbc.co.uk/news/health-54696873

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#660
post #226

Earlier quoted context omitted.

Read the papers on it, antibody tests in people who have previously tested positive for covid have found little or no antibodies in tests taken 3 months after infection. So it appears as if there is a limited/short term immunity after initial infection. The vaccine appears to produce a much stronger immune response, such that antibodies can be identified in tests some time after the vaccination. You can get limited i…

antibodies disapear quickly, but the B-memory cells that produce them are still in the body ready to be mobilized. "Common cold" and "flu" is not 1 virus, but hundreds of different viruses which is why you get them repeatedly. You do build immunity though. It's why children always have a cold and adults a lot less common.

https://www.bbc.co.uk/news/health-54696873
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