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Vaccine hopes rise as Oxford jab prompts immune response among old and young

reuters.com

121–130 of 712 posts

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#121

This article reinforces that herd immunity between young healthy people would have been the best solution. Our old are going to get sick from vaccines, so the young are going to get it anyway. Next year under 50 year olds will line up for their vaccine. Meanwhile 1.5 years worth of old, obese, and sick people will have died from coronavirus. Wouldn't it have been better if healthy kids and adults caught it in q2 2020…

I was considering bug chasing and then isolating. I regret not doing so.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#122

Earlier quoted context omitted.

I think you're vastly overestimating our capacity to build enough vaccines and distribute them over the world, as well as dealing with those who will refuse to vaccinate. Even if we had a vaccine ready for the roll-out today, I don't see us going back to normalish until late 2021 at earliest. As with any vaccine, you'd need about 80% of the population to vaccinate in order for herd immunity to kick in. I feel like we…

Various experts are predicting that the winter will be quite bad. See for example: https://covid19.healthdata.org/global?view=infections-testin... https://covid19.healthdata.org/united-states-of-america?view... But notice, in the latter chart, that in the US the number of infections is predicted to peak in January and then start going down. It seems plausible that by March, we'll achieve some level of herd immunity,…

It's been estimated that 80% of the population needs to have been infected to achieve herd immunity. That means ~240 million people in the United States need to be infected. We're at 8.7 million infected. No way we get herd immunity anytime soon.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#123

Earlier quoted context omitted.

Why would old people get sick from the vaccine? If we let everyone get it in Q2 2020, millions would have died when we ran out of ventilators.

> If we let everyone get it in Q2 2020, millions would have died when we ran out of ventilators. How do you explain countries like Belarus, Serbia and Sweden, or parts of the US like South Dakota, where no or very lax measures were taken but what you describe didn’t happen? In fact, is there any evidence that this happened anywhere, or is it all just conjecture based on modeling?

Probably too early to tell about South Dakota, to be honest. Let's see what things look like in a few months.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#124

Not knowing anything about big pharma, does Astrazeneca make all the money here? How much does a vaccine like this cost per person given the scale of the distribution and manufacturing?

Usually there is an IP agreement. Also, ever notice the media calls it “Oxford study/vaccine” for good news and “Astrazeneca study/vaccine” when it’s bad news (like a few weeks ago when they had to shutdown to multiple people getting an unknown illness).

I work in an area where we make agreements with university’s. It’s often shared IP or publicity. Alternatively, one can publish, once the other makes profits. Or it could be something in between.

In this case, I bet everyone is doing this pro-Bono from a future profit perspective, because the government is paying for all of it.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#125

Earlier quoted context omitted.

Why would old people get sick from the vaccine? If we let everyone get it in Q2 2020, millions would have died when we ran out of ventilators.

> If we let everyone get it in Q2 2020, millions would have died when we ran out of ventilators. How do you explain countries like Belarus, Serbia and Sweden, or parts of the US like South Dakota, where no or very lax measures were taken but what you describe didn’t happen? In fact, is there any evidence that this happened anywhere, or is it all just conjecture based on modeling?

Last I checked Sweden had 110k cases and 5.5k dead. That's an almost exactly 5% fatality rate. Compare that to neighbouring Denmark with 40k cases and 700 dead gives you a 1.75% fatality rate.

Seems to me that there is good basic evidence right there for Sweden's approach being much more deadly.

We can argue back and forth about the relative value of freedom vs lives or whether Denmark will ultimately have as many dead etc. But right now, it seems that controlling numbers saves lives...

https://www.google.com/search?q=sweden+covid+deaths&rlz=1C1G...

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#127
post #60

Earlier quoted context omitted.

It's definitely good news. Though, sometimes people think vaccines just prevent someone getting a disease. Stop it completely in its tracks. That's true for some, but it's not that simple for others. Unfortunately a measured immune response does not ensure: - That the virus can't be transmitted to others - That you are less likely to catch and replicate the virus - That you can't get ill from the virus - That you can…

The virus cannot replicate, the genetic material inside the virus cannot create new viruses as in there are no instructions inside the payload to replicate and assemble new virions. To make the virus for the vaccine you need to use a different virus that when it replicates it creates copies of the actual virus used in the vaccine. Think about it as a self extracting archive that creates copies of an uncompressed file…

Thanks.

I guess the thought is that a really unlucky evolutionary accident would be when the other virus capable of replicating and the vaccine meet in a body, and by chance transfer some of those instructions across. I presume that's rare or never seen, but I don't know, and (with a safety-engineering mindset on) I'd automatically consider that a "chance" unless it is ruled out by something.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#128
post #61
post #32

Earlier quoted context omitted.

if we're back to normalish by spring next year I think that would be a great outcome, if the messaging to the public would be, buckle down until then I think lockdown complaince could go up

I dont think any expert is predicting normalish by next spring, maybe in a years time if we're lucky. https://www.msn.com/en-us/health/medical/the-who-says-health...

Meanwhile the general populace cares less and less, so we may be back to normal in the spring regardless.

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#129

Bet you they give it to everyone for free everywhere in the world except for the USA, where they charge 600 dollars a dose and consequently we never reach herd immunity and have endemic Covid indefinitely.

800 for the dose, 300 for a list of other things on the bill, and you're required by law to get the injection today. if you can't afford it, that's prison time, where you'll get the vaccinee but also need to work for the bill, probably producing maga-caps or substituting sick/dead medical personnel.

eagle screeches

are we there yet?

Re: Vaccine hopes rise as Oxford jab prompts immune response among old and young

#130
post #41
post #5

Earlier quoted context omitted.

This IS good news. Now (soon, hopefully) people can acquire immunity through a vaccine, instead of through a virus that leaves long-lasting damage to the body (in particular, but not limited to, the brain).

> leaves long-lasting damage to the body (in particular, but not limited to, the brain). In what percentage of people who get COVID-19 is there long-lasting damage to the body? What other conditions did the people who get long-lasting damage to the body have? How does these numbers compare with other diseases? Would appreciate citations.

Nobody had it long enough ago to answer that. SARS-CoV-1 (1) patients have suffered years afterwards, see e.g. this article from 2010:

https://www.thestar.com/life/health_wellness/2010/09/02/sars...

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