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The First Randomized Controlled Trial on Vitamin D and Covid-19

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Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#161

Post by icedchai »

azinman2 wrote: post #61
JabavuAdams wrote: post #46

Earlier quoted context omitted.

You should almost certainly be going outside for the other health benefits. There's very little risk of transmission if you're outside and 2m away from other people, even if intermittently you're closer than that. Even more so if one or the other of you is masked. Places to be more concerned about are bottlenecks like lobbies and elevators on the way to/from outside.

My understanding is that it hasn’t been shown for elevators. I think this is because of the required time to breathe in a minimal viral load. Do you have evidence otherwise?

You're in a confined space, breathing the same air as other people. Also, given the frequent traffic of elevators, consider what you may breath in from previous occupants. This sounds risky to me. I hate touching elevator buttons during normal times. I'd wear masks and gloves.

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#162

Post by manmal »

Giorgi wrote: post #123
jonplackett wrote: post #114

Surly now it's time to just start giving everyone some free vitamin D. Best case scenario: Less dead people. Worst case scenario: We all have healthier bones.

Free vitamin D? Like... Sun?

During the summer months, long sun exposure should suffice, yes. But the November sun (if any) will not do much for your vitamin D status.

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#163

Post by burfog »

jogundas wrote: post #23
LinuxBender wrote: post #16

Earlier quoted context omitted.

Hydroxychloroquine is a zinc ionophore which helps zinc get into the cells in your lungs and slows the viral replication. It was not designed to be used this way, it just happens to work. This is mostly useful before your viral load is high. Same goes for Quercetin, also a zinc ionophore. They are good proactive measures to slow down the viral transcription before you reach a critical stage. It won't help everyone, e…

Wiki says that "Hydroxychloroquine is being studied to prevent and treat coronavirus disease 2019 (COVID‑19), but all clinical trials conducted during 2020 found it is ineffective and may cause dangerous side effects." https://en.wikipedia.org/wiki/Hydroxychloroquine

Wikipedia is pretty reliable for math, old computer hardware, and other dry technical subjects.

This is not one. This is a political subject. Wikipedia is a complete disaster for anything that even remotely touches upon modern politics. There are teams of people paid to impose an opinion on Wikipedia, relentlessly wearing down any neutral editor with 24x7 edits and every kind of bureaucratic fight. The people who edit for free are also pulled from a highly-biased population, with strong overrepresentation by unemployed single people with non-STEM degrees.

Simply put, "ineffective and may cause dangerous side effects" is a purely political attack on the US president.

Last year, the drug was handed out freely, with very little worry, to anybody claiming that they would visit a country with malaria. In many places it is non-prescription. Clearly, the "dangerous side effects" aren't such a big deal. You can get deadly "dangerous side effects" from aspirin (Reye syndrome) and from Tylenol/paracetamol/acetaminophen (complete liver failure).

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#164

Post by tboyd47 »

blithedale wrote: post #143
tboyd47 wrote: post #118

Good on you, Spain. A study like this could never take place in the USA :( Too many powerful people are heavily invested in the belief that there is no treatment for it.

There are seven results for American trials found on clinicaltrials.gov for Condition= "COIVD19" and Drug = "VitaminD" run by institutions like Harvard/MGH, Brigham, UNC, Arizona State University, etc. https://clinicaltrials.gov/ct2/results?term=vitamin+d&cond=C...

Thank you. Perhaps my stance is too cynical.

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#165

Post by sokoloff »

jonplackett wrote: post #114

Surly now it's time to just start giving everyone some free vitamin D. Best case scenario: Less dead people. Worst case scenario: We all have healthier bones.

Vitamin D pills look to be 3-5¢ per day. Hardly seems like something I’d be supportive of creating a “free” supply chain for.

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#166

Post by mypalmike »

ghaff wrote: post #137
erentz wrote: post #104

Earlier quoted context omitted.

Greater than 70% of African Americans are suspected to be Vit D deficient. Definitely worth getting tested if you can [1] especially if you live in the more northern latitudes. Doubly so during winter. [1] with the note that generally insurance is a real PITA with vitamin D testing. The trick usually is to list as a diagnosis code a previous history of low vitamin D. Yes it’s like a catch 22. You need prior testing s…

>generally insurance is a real PITA with vitamin D testing FWIW, vitamin D has been among the things tested when I have my blood work for an annual physical and never had any insurance issue about it. And I do take supplements because it was low.

Interesting. I had to pay something like $100 out of pocket for my recent vitamin D test (unsurprisingly it was low).

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#167

Post by burfog »

notadoc wrote: post #97
jogundas wrote: post #23

Earlier quoted context omitted.

Wiki says that "Hydroxychloroquine is being studied to prevent and treat coronavirus disease 2019 (COVID‑19), but all clinical trials conducted during 2020 found it is ineffective and may cause dangerous side effects." https://en.wikipedia.org/wiki/Hydroxychloroquine

Wikipedia is not a reliable source for anything, let alone medical information or studies

It's pretty good for purely non-political things.

Sadly, this is political.

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#168

Post by intotheabyss »

blithedale wrote: post #138
jonplackett wrote: post #114

Surly now it's time to just start giving everyone some free vitamin D. Best case scenario: Less dead people. Worst case scenario: We all have healthier bones.

The worst case scenario isn't 'healthier bones'. It's kidney failure - https://www.cmaj.ca/content/191/14/E390 Or fatal hypercalcemia - https://link.springer.com/article/10.1007/s12098-016-2109-z And so on. I frankly think its irresponsible and facile for anyone to suggest there are no downsides to high doses of Vitamin D. This stuff is available OTC and a lot of folks are just gonna dose themselves ad libitum here.

We get 20,000 iu of Vitamin D in like 15 to 30 minutes of sun (if you're pale skinned). Pretty sure taking 5,000 iu every day isn't going to be harmful.

Also, fun side note: Vitamin D is produced as an oil on the skin and actually seeps through your skin overtime to enter the bloodstream. So don't take a shower after getting some sun, because you could be washing off your Vitamin D.

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#169

Post by autisticcurio »

andy_ppp wrote: post #77
arkitaip wrote: post #63

Earlier quoted context omitted.

You would have to take crazy amounts of vitamin D - more than 250 mcg (10000 IU) - for it to be toxic [0][1]. [0] https://academic.oup.com/ajcn/article/85/1/6/4649294 [1] https://asbmr.onlinelibrary.wiley.com/doi/full/10.1359/jbmr....

Over a prolonged period of time...

I got my D3 levels up to 478nmol/L according to the UK NHS Vit D blood spot service. Supplemented up to starting point of around 200-240nmol/L and then spent the summer outside with top off working on laptop. Never felt so good. Bought some Lizard flo tubes after that to bask under after I was craving a suntan one winter. Odd feeling, but I was also doing alot of magnesium sulphate (Mag oil) topically which helps and some zinc orally. The Mag oil stings the skin much like Deep Heat, so be warned and thinner skinned individuals will experience more pain.

400mg = 400000mcg = 16000000ui https://www.azcalculator.com/calc/vitamin-d-mcg-iu-converter...

Re: The First Randomized Controlled Trial on Vitamin D and Covid-19

#170

Post by giardini »

ReflectedImage wrote: post #36
schoolornot wrote: post #13

Earlier quoted context omitted.

The American media would have you believe that hydroxychloroquine and Z-packs are completely ineffective. Are we still in the "we don't know" stage? Is there any conclusive data to show that it helps/hurts/or does nothing in the beginning/middle/end stages of infection?

There are other drugs now that both work and have a large effect (20%). Hydroxychloroquine possible 5% increase in survival rate pales in comparsion. Given it's also poisonous I don't see why you would want to use it.

ReflectedImage says>"There are other drugs now that both work and have a large effect (20%). Hydroxychloroquine possible 5% increase in survival rate pales in comparsion. Given it's also poisonous I don't see why you would want to use it."

Please name the other drugs that "both work and have a large effect (20%)".

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