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Glucosamine Supplementation Reduces All-Cause Mortality: Study

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Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#111
post #3

The paper this is based on, which might be a better link: https://ard.bmj.com/content/79/6/829

The study says the participants were 62% female, overwhelmingly ate more vegetables and supplements, exercised more than the control group, were mostly white, as well as self reported glucosamine supplementation - without dosage information. Overall it might be more indicative of wealth, education, and fitness than the effect of glucosamine. The paper itself says it’s not able to differentiate the effect from lifesty…

The confounders are, as you point out, incredible.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#112
post #97
post #94

All-Cause Mortality? Is it make you also somehow immune to fire arms for example? Just the title makes the article to view unserious.

>Is it make you also somehow immune to fire arms for example? No, you have to start off with daily injections of small arms fires (think .22 caliber) in order to begin building immunity. Over time you gain immunity and then can work your way up to larger calibers.

Reminiscent of the biological testing approach here:

https://xkcd.com/1217/

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#113
Probably because those who are old start moving again with lower joint pain.

My 80 year old grandfather is the most fit person I know. Super healthy, but literally lifts rocks and gardens every day.

To contrast other family members are in their 50s with diabetes and heart conditions.

Keeping active is key. Remove peoples joint pain (which is what this supplement is used for) and of course they reduce mortal across the board.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#114

https://examine.com/supplements/glucosamine/ Always used this site when trying to find unbiased information, and also not be to hyped about a single study. However now the effect matrix is hidden behind a paywall. When talking about joint health: As a young and very active person my biggest problem is overtraining injuries. Wish I knew how to be able to train as much as I would like to, with just a simple supplement…

Look up Keith Baar. He has some suggestions.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#115

Probably because those who are old start moving again with lower joint pain. My 80 year old grandfather is the most fit person I know. Super healthy, but literally lifts rocks and gardens every day. To contrast other family members are in their 50s with diabetes and heart conditions. Keeping active is key. Remove peoples joint pain (which is what this supplement is used for) and of course they reduce mortal across th…

Props to your grandfather. I can barely lift even a small garden.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#116
post #97
post #94

All-Cause Mortality? Is it make you also somehow immune to fire arms for example? Just the title makes the article to view unserious.

>Is it make you also somehow immune to fire arms for example? No, you have to start off with daily injections of small arms fires (think .22 caliber) in order to begin building immunity. Over time you gain immunity and then can work your way up to larger calibers.

That was one of the low key funniest things I’ve ever read on hacking news

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#117
post #55

If you are interested in digging into this stuff, and what really works medically/scientifically based on reviewed evidence and sources such as Cochrane Reviews, I can't recommend Dr Stanfields youtube channel high enough: https://www.youtube.com/c/DrBradStanfield/videos Also here is his video on Sulforaphane which Glucosamine activates. He goes into detail as to how this mechanism works. Because of his video/latest…

Thank you for a very curious channel, I'm going to watch it all. Why does the doctor look so weird anyway? I mean his eyes - sort of a crazy gaze. Isn't he blind or something? Or is that an effect of a medication he takes?

This is a video where he uses natural light and his eyes look normal. It is just bad lighting. https://www.youtube.com/watch?v=5kzaj-_vr1w

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#118

are there dietary sources of glucosamine?

Yes - cartilage. If you eat chicken or something like that, eat the cartilage. You can do this on pre-cooked chickens you get from Sam's Club / Costco. If you eat chicken breasts only (which a lot of health-conscious people do), you don't get this benefit. I talked to Dr.Yang Jwing Ming (one of the few Kung Fu practioners with a Western phd and he said eating cartilage is one of the best ways to help reduce the risk…

Another great way to get cartilage is with chicken soup, slow cooked until the gristle liquefies in to the soup. It's more absorbable by the body that way. Chicken fat is great for the skin, too. Easy and cheap to cook - just get a whole hen and simmer it in water in a big pot, or use a crock pot.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#119
post #24

I've been supplementing glucosamine along with a large amount of other things for awhile now. I'm not too bullish on it in humans, but it doesn't seem like it hurts, and is definitely cheap: https://nearcyan.com/supplements My latest favorites that I'm a bit more hopeful for are glycine, spermadine, and rapamycin.

Interesting you take rapamycin and a bunch of other stuff thats supposed to extend lifespan. I wish to see if you live longer but I'll probably die first lol. Serious questions: have you experimented with calorie restriction? Clearly thats THE method that works in every species. Second question: do you battle with depression? My current hypothesis is that any life extending drug will also inevitably lead to depressio…

Yes, I generally have been doing quite a bit of intermittent fasting, fasting, and caloric restriction. But not very strictly so, only sometimes.

I have before, but I would say it's not too bad right now.

Re: Glucosamine Supplementation Reduces All-Cause Mortality: Study

#120
post #3

The paper this is based on, which might be a better link: https://ard.bmj.com/content/79/6/829

The study says the participants were 62% female, overwhelmingly ate more vegetables and supplements, exercised more than the control group, were mostly white, as well as self reported glucosamine supplementation - without dosage information. Overall it might be more indicative of wealth, education, and fitness than the effect of glucosamine. The paper itself says it’s not able to differentiate the effect from lifesty…

That is possible but the large sample size may help. The study involved roughly a half million people with around one hundred thousand supplementing with glucosamine. With that many people and these big numbers the results are rather strong.
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