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Quote: "Glucosamine is a polysaccharide that is found naturally in cartilaginous joint tissues, bones, skin, ligaments, and nails" Why not just eat natural sources like cartilage, bone broth, skin etc ?
Regular glucosamine supplementation was associated with lower mortality due to all causes, cancer, CVD, respiratory and digestive diseases.
If you are interested in digging into this stuff, and what really works medically/scientifically based on reviewed evidence and sources such as Cochrane Reviews, I can't recommend Dr Stanfields youtube channel high enough: https://www.youtube.com/c/DrBradStanfield/videos Also here is his video on Sulforaphane which Glucosamine activates. He goes into detail as to how this mechanism works. Because of his video/latest…
The paper this is based on, which might be a better link: https://ard.bmj.com/content/79/6/829
Earlier quoted context omitted.
As someone that has taken various vitamins and supplements over the years, glucosamine is the one where I truly feel a difference. In my knees, my back stopped cracking when I woke up, and generally just better. Others I take based on blood tests if something is out of whack for a time.
What brand and dosage do you take?
The paper this is based on, which might be a better link: https://ard.bmj.com/content/79/6/829
> Third, regular glucosamine use may be a marker for a healthy lifestyle, but it is hard to distinguish the confounding effects of a healthy lifestyle from the impact of regular supplementations in an observational study. Although we had carefully adjusted for potential confounding lifestyle-related factors in our analyses, we could not exclude the possibility that the results were confounded by unmeasured lifestyle-related factors. In general, with the current observational study design the possibility of residual confounding due to imprecise measurements or unknown factors cannot be excluded for all findings in our study, despite our careful adjustment of all measured confounders.
I wonder if humans used to eat more bones ... I had a physical anthropology professor who studied an ancient site in east Africa where it appeared humans got a fair amount of food from eating leftovers from lions and whatnot, breaking open bones and eating marrow. Basically humans were in between the predators and the vultures.
I've given glucosamine to my dogs for years, and I can clearly notice a difference in their joint health and how stiff and sore they are after long runs ('long-run': 15-25 miles, measured on GPS collars). When I run out of glucosamine, or just drop off of giving it to them for whatever reason, I see them fall back pretty quickly. And when I restart them on it, I notice a response in a few days. I also give give them…