Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes • Hacker News Board

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#141

Post by gshdg » Sun, Jun 21, 2020, 12:21 PM UTC

ardit33 wrote: post #62

gshdg wrote: post #42

Earlier quoted context omitted.

Not a ton of carb calories in lettuce, kale, spinach, broccoli, etc. They’re mostly composed of insoluble fiber (from which ruminants can extract calories but humans can’t) and water. A “low carb” diet doesn’t exclude high amounts of insoluble fiber. It excludes high amounts of carbohydrate calories.

This is not getting through... If you are consuming your 2000 calories diet, and it is coming from plants, you are still ingesting 2000 calories worth of carbs..... 1 kg of feathers, and 1 kg of iron, weight the same.... The feathers will be large and take more volume, while the iron will be small and more dense. Same with foods.... if your plant based diet you are consuming 2000 worth of bio-available calories, then…

Nope, in a low carb plant based diet, most of your calories tend to come from fats with some from protein.

There are plenty of fats in nuts and legumes, which are compatible with a low carb (even if not a zero carb) diet. Seeds are also rich in fats (and are the source of many vegetable oils).

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#142

Post by nick0garvey » Mon, Jun 22, 2020, 5:25 AM UTC

bytelane wrote: post #95

nick0garvey wrote: post #45

Earlier quoted context omitted.

It's expensive but not as bad as you'd think. I didn't have insurance for half a year, and I just called the manufacturer and got a huge discount ($200/bottle -> $35/bottle). One bottle lasts a month or so. This was only due to not having insurance and wasn't need-based - I had earned FAANG income earlier that year and the year before.

Just curious, which manufacturer did you call, Eli Lilly or Novo Nordisk? I think the details of how you were able to get a discount would be beneficial to others. I am a type 1 and I recently heard of another type 1 who recently died at age 40 because he lost his job+insurance and was rationing insulin.

I called Lilly, but both manufacturers have programs to help. These two are need-based. I didn't qualify but still got a sharp discount.

https://www.lillycares.com/aboutlillycares.aspx https://www.novocare.com/diabetes-overview/let-us-help/pap.h...

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#143

Post by arkades » Mon, Jun 22, 2020, 3:59 PM UTC

entitydc wrote: post #120

arkades wrote: post #101

Earlier quoted context omitted.

What does CHD stand for in this context?

Coronary heart disease. CVD (cardiovascular disease) may be more appropriate as it’s less specific but still covers the linkage between the two conditions. http://journal.diabetes.org/diabetesspectrum/99v12n2/pg81.ht...

Thank you.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#144

Post by firethief » Mon, Jun 22, 2020, 6:18 PM UTC

eebynight wrote: post #108

firethief wrote: post #92

Earlier quoted context omitted.

Keto diets have most definitely not been around long enough for anyone's bodies to evolve to follow them. That takes many thousands of years.

Why would our bodies need to evolve to follow them when the mechanisms are already built-in? Our body already contains the necessary pathways, enzymes and processes to switchover to utilizing fat as fuel. We quite literally evolved to do this... That being said, I think this adaption was more of an energy conservation mode for when food was scarce rather than our ancestors intentionally eating in a ketogenic compatib…

> That being said, I think this adaption was more of an energy conservation mode for when food was scarce rather than our ancestors intentionally eating in a ketogenic compatible manner.

Yeah, that's the point I was trying to make. I am aware that humans have the capability of surviving on a ketogenic diet, but that doesn't support the argument I was replying to that following such a diet is what we evolved to do.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#145

Post by firethief » Mon, Jun 22, 2020, 6:21 PM UTC

narag wrote: post #107

firethief wrote: post #92

Earlier quoted context omitted.

Keto diets have most definitely not been around long enough for anyone's bodies to evolve to follow them. That takes many thousands of years.

The diet of primitive humans was more similar to keto than to current developed country diets and it was in place for hundreds of thousands of years. The first big change was from agricultural civilizations in neolithic, less than ten thousands year ago. Current diet is at most a hundred years old. And specifically the diet that is causing so many problems is only fifty years old.

Typical diets these days are pretty bad. But few, if any, societies of anatomically modern humans have lived under conditions where they would almost always be in ketosis, so evolutionary history doesn't provide a reason to think that we are best adapted to that being our normal state.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#146

Post by KerryJones » Mon, Jun 22, 2020, 10:23 PM UTC

rantwasp wrote: post #82

KerryJones wrote: post #50

Earlier quoted context omitted.

LDL is correlated but not causative and it's been discovered that HDL is a much better indicator. Take a look at this book: https://www.amazon.com/Big-Fat-Surprise-Butter-Healthy/dp/14... It goes into it quite a bit more -- cholesterol is a _terrible_ indicator of overall health. This is well known in the Keto community.

when you use LDL, HDL and cholesterol interchangeably this tells me that you don’t know what you’re talking about. Cholesterol itself is part of the lipid membrane of every cell. It’s essential. When people say “high cholesterol” they usually talk about high cholesterol carrying lipo-proteins in the bloodstream. high ldl is definitely a risk factor for CHD

I didn't use them interchangeably...? Did you mean to refer to someone else?

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#147

Post by KerryJones » Mon, Jun 22, 2020, 10:24 PM UTC

krustyburger wrote: post #117

KerryJones wrote: post #50

Earlier quoted context omitted.

LDL is correlated but not causative and it's been discovered that HDL is a much better indicator. Take a look at this book: https://www.amazon.com/Big-Fat-Surprise-Butter-Healthy/dp/14... It goes into it quite a bit more -- cholesterol is a _terrible_ indicator of overall health. This is well known in the Keto community.

And the opposite is well known in the Whole Foods Plant-Based community. I don’t have a horse in this race but appeals to authority when it comes to the science of diet are highly suspect.

Nah, I used to be on a plant-based diet -- have done quite a bit of research. This is _not_ well known in the community, but sure, a few under-researched people in the group might say that has to do with it.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#148

Post by labelbias » Tue, Jun 23, 2020, 11:03 AM UTC

PKop wrote: post #28

vbtemp wrote: post #4

I was on a low-carb diet for a while. Loved it. Felt great. Was totally fit. All my digestive problems cleared up. I would never get "hangry". By every single subjective measure my quality of life and sense of well-being improved. Then I got my cholesterol checked during a routine blood work and it was through the roof. WTF? Anyone know better than me about this?

Your assumptions about high cholesterol being bad are wrong, simple as that. Just as a few decades ago, the popular (even as agreed upon within medical industry) assumptions about "low fat" were wrong. In other words, the measurement you observed was good . Your brain needs that measured value you were tested at to be high. Your health would suffer if it wasn't. There is tons of research and discussion about this onl…

Masai all have atherosclerotic plaque build up and it is also present in their children. Childhood with plaque forces various adaptations to blood vessels. They get wider and more elastic to counter the reduced blood flow and rigidity.

Anyone who isn't a child won't be able to make these adaptations and anyone who isn't on a starvation mimicking diet but is trying to gain or maintain weight on diets filled with dietary cholesterol will almost certainly start building up plaque.

Yes, dietary cholesterol has a low effect on blood serum cholesterol after some amount. So yes, increasing the consumption of eggs from 5 to 10 a day won't linearly effect the blood serum cholesterol.

Problem with fasting mimicking diets is that they are not a cure and are not long-term.

Also, consuming only things that are easy to digest makes you digestion more fragile to varying stimuli in the future. Which is why people who are on these "rejuvinating" diets for a longer period of time tend to experience their disease symptoms much quicker when they go back to eating vegetables rich in antinutrients.

Here's a very nice study where all Masai participants had atherosclerosis. Some even died from heart disease being less than 20 years of age: https://academic.oup.com/aje/article-abstract/95/1/26/167903

"These pastoral people are exceptionally active and fit and they consume diets of milk and meat. The intake of animal fat exceeds that of American men. Measurements of the aorta showed extensive atherosclerosis with lipid infiltration and fibrous changes but very few complicated lesions. The coronary arteries showed intimal thickening by atherosclerosis which equaled that of old U.S. men. The Masai vessels enlarge with age to more than compensate for this disease. It is speculated that the Masai are protected from their atherosclerosis by physical fitness which causes their coronary vessels to be capacious."