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Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

diabetes.co.uk

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Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#91

Post by JamesBarney »

PKop wrote: post #28
vbtemp wrote: post #4

I was on a low-carb diet for a while. Loved it. Felt great. Was totally fit. All my digestive problems cleared up. I would never get "hangry". By every single subjective measure my quality of life and sense of well-being improved. Then I got my cholesterol checked during a routine blood work and it was through the roof. WTF? Anyone know better than me about this?

Your assumptions about high cholesterol being bad are wrong, simple as that. Just as a few decades ago, the popular (even as agreed upon within medical industry) assumptions about "low fat" were wrong. In other words, the measurement you observed was good . Your brain needs that measured value you were tested at to be high. Your health would suffer if it wasn't. There is tons of research and discussion about this onl…

Just an addendum to people who aren't familiar with medical research. This is way outside of mainstream medical practice, and 95% of researchers in the field believe cholesterol matters, statins have saved more lives than any other drug, and they improve cognition in most cases.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#92

Post by firethief »

PKop wrote: post #67
rantwasp wrote: post #40

Earlier quoted context omitted.

so. this is so general that it’s not helpful. what ranges are we talking about? also, when people talk about cholesterol they usually don’t mean cholesterol they mean lipi-proteins that carry the cholesterol through the blood (cholesterol needs this as it’s hydrophobic). LDL from those lipo-proteins is definitely correlated with heart disease. Here, read about it in more detail than you probably need to know: https:/…

>this is so general that it’s not helpful I think digging into the minutiae of specific numbers is silly, when the better frame is to construct the right diet the comports w/ human evolution and lifestyle, energy, activity and go from there. Generally low carb (particularly avoiding high glycemic index carb, and sugars) preferring lower starch vegetables, while prioritizing animal fats, meat, fish. Keto / keto carniv…

Keto diets have most definitely not been around long enough for anyone's bodies to evolve to follow them. That takes many thousands of years.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#93

Post by virtuallynathan »

rantwasp wrote: post #55
dragonfax wrote: post #11

Earlier quoted context omitted.

The Ketoers say this isn't a problem. That cholestorol is misunderstood, and high values are only bad if you eat high carbs. If your low carb then the high value is actually normal and healthy. But YMMV

sorry but this is bs and straight dangerous. cholesterol itself is not dangerous but the proteins that carry it in the blood stream are. That’s why LDL is bad and HDL is good (supposedly 2 types of cholesterol- but they’re not they’re two types of proteins). The LDL are the smaller ones that actually end up, in time, piercing the lumen (blood vessel wall) and causing inflammation. this is how your arteries narrow and…

“piercing the lumen” is a drastic over-simplification. We don’t know how much LDL is in a healthy lumen (the small amount of research that exists suggests its greater than the serum concentration). Much of it gets there via active transport mechanisms (transcytosis).

Also, why would an endogenously produced protein end up killing you? Seems like evolution run-amok.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#94

Post by inetsee »

Kye wrote: post #75
nick0garvey wrote: post #45

Earlier quoted context omitted.

It's expensive but not as bad as you'd think. I didn't have insurance for half a year, and I just called the manufacturer and got a huge discount ($200/bottle -> $35/bottle). One bottle lasts a month or so. This was only due to not having insurance and wasn't need-based - I had earned FAANG income earlier that year and the year before.

Both those prices seem excessive.

These prices are not high. I went through a period when I had no health insurance, and I had to rely on generic insulin, the kind you can buy at Walmart for $25 a vial. I have insurance now and the insulin I take now costs me a co-pay of $100 a vial. Paying $35 a vial without insurance is not bad at all.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#95

Post by bytelane »

nick0garvey wrote: post #45
rhinoceraptor wrote: post #35

Earlier quoted context omitted.

Hugely reducing insulin dosing is still probably valuable, especially for Americans since it's so expensive.

It's expensive but not as bad as you'd think. I didn't have insurance for half a year, and I just called the manufacturer and got a huge discount ($200/bottle -> $35/bottle). One bottle lasts a month or so. This was only due to not having insurance and wasn't need-based - I had earned FAANG income earlier that year and the year before.

Just curious, which manufacturer did you call, Eli Lilly or Novo Nordisk? I think the details of how you were able to get a discount would be beneficial to others. I am a type 1 and I recently heard of another type 1 who recently died at age 40 because he lost his job+insurance and was rationing insulin.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#96

Post by anchpop »

ovi256 wrote: post #90
Kye wrote: post #75

Earlier quoted context omitted.

Both those prices seem excessive.

The best part of economic freedom is that one is free to start a manufacturer delivering a cheaper whatever one is complaining is too expensive!

It's possible the price is too high, but the reason it has that price $35/bottle is the minimum required to sustainably produce it. It's well accepted in economics that price of manufacture is not necessarily the societally optimal price [0]. If this is the case, what needs to be done is government subsidization, and no individual person can just start a company and do it themselves.

Also, the idea that everyone is free to start manufacturing insulin ignores the billions of dollars of capital that is required to create a FDA-compliant insulin production plant, which almost no one on earth has access to.

[0]: https://www.investopedia.com/terms/e/externality.asp

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#97

Post by messe »

inetsee wrote: post #94
Kye wrote: post #75

Earlier quoted context omitted.

Both those prices seem excessive.

These prices are not high. I went through a period when I had no health insurance, and I had to rely on generic insulin, the kind you can buy at Walmart for $25 a vial. I have insurance now and the insulin I take now costs me a co-pay of $100 a vial. Paying $35 a vial without insurance is not bad at all.

It's a hell of a lot higher than most developed nations. Here in Ireland, as far as I'm aware, it's free thanks to the long term illness scheme. (We have both public and private healthcare available)

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#98

Post by arexxbifs »

ovi256 wrote: post #90
Kye wrote: post #75

Earlier quoted context omitted.

Both those prices seem excessive.

The best part of economic freedom is that one is free to start a manufacturer delivering a cheaper whatever one is complaining is too expensive!

"Not only are the big three insulin manufacturers financially opposed to biosimilars entering the market, they’ve actively taken legal steps to prevent it."

https://beyondtype1.org/how-much-does-it-cost-to-produce-ins...

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#99

Post by RHSeeger »

1123581321 wrote: post #73
Trasmatta wrote: post #36

Earlier quoted context omitted.

Yep. When I've consciously gone low carb, my insulin requirements have gone down, and my blood sugar was much more manageable. But if I had stopped taking insulin entirely I would have died or ended up in the hospital with DKA.

With this regimen, you would simply do as your blood sugar numbers direct. It sounds like these patients were measuring and found their glucose to be too low if they took any insulin. In that case, it is safe to stop if coordinated with a doctor. There shouldn’t be any point where a decision is made to drop insulin permanently while your reads are high. Even if stopping insulin prematurely, low carb would mean low ri…

> With this regimen, you would simply do as your blood sugar numbers direct.

That's true of every regimen, though.

Re: Low carb diet leads to “clinical remission” in 3 cases of type 1 diabetes

#100

Post by dogma1138 »

Kye wrote: post #75
nick0garvey wrote: post #45

Earlier quoted context omitted.

It's expensive but not as bad as you'd think. I didn't have insurance for half a year, and I just called the manufacturer and got a huge discount ($200/bottle -> $35/bottle). One bottle lasts a month or so. This was only due to not having insurance and wasn't need-based - I had earned FAANG income earlier that year and the year before.

Both those prices seem excessive.

The NHS (how much it pays not the patient) annual costs are about £400 so it doesn’t seem excessive
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