171–180 of 190 posts
Imagine how much Theranos would have been worth right now. I think cost firstly and then speed of result would be useful right now never mind the throughput.
You need stuff that works first.
Sounds really impressive, but writing "1,000 tests per day with just 100 devivces" is really marketing BS I think. They should've just written "10 tests per day per device".
> Sounds really impressive, but writing "1,000 tests per day with just 100 devivces" is really marketing BS I think. Correct. > They should've just written "10 tests per day per device". Incorrect. Marketing BS works.
This is not rapid, only 10 tests/day, whilst the current overly slow sequencers can do 200/day. The accuracy of 5% is also worse than other faster sequencers of 3%. And compare that to modern ThermalFischer parallel PCR sequencers, which operate in realtime, 25 tests in parallel, for 2.500€. That's a factor of 1000. With 10 modern sequencers per city you could test 10.000 per day, eg with drive-in. https://www.thermo…
In addition to all information above this test is able to detect antibodies only not virus. So it is not recommended tests by WHO. This test is only useful in the later part of infection by the time which patient might have in contact with others thus spreading the disease. We need tests which can detect single of very few virus particle in the early stage of infection and that will help to quarantine the patient thu…
Earlier quoted context omitted.
In addition to all information above this test is able to detect antibodies only not virus. So it is not recommended tests by WHO. This test is only useful in the later part of infection by the time which patient might have in contact with others thus spreading the disease. We need tests which can detect single of very few virus particle in the early stage of infection and that will help to quarantine the patient thu…
...able to detect antibodies only not virus...This test is only useful in the later part of infection Actually, getting a sense of the penetration of infection into the general population, among asymptomatic people and mild cases would be very valuable information! Antibody tests could be used to sample test the public at large.
I don't think this is meant to replace large labs running rtPCR tests.
Earlier quoted context omitted.
plus in the current context, false negatives are much more dangerous than false positives
Not necessarily. Hospitals in an epidemic are major spreaders of the infection. If false positive results lead to patients being put together with real carriers, they will soon be infected. From a recent report[1] from Italy: > For example, we are learning that hospitals might be the main Covid-19 carriers, as they are rapidly populated by infected patients, facilitating transmission to uninfected patients. Patients…
Seems like that would be handy if not just fascinating
This is not rapid, only 10 tests/day, whilst the current overly slow sequencers can do 200/day. The accuracy of 5% is also worse than other faster sequencers of 3%. And compare that to modern ThermalFischer parallel PCR sequencers, which operate in realtime, 25 tests in parallel, for 2.500€. That's a factor of 1000. With 10 modern sequencers per city you could test 10.000 per day, eg with drive-in. https://www.thermo…
Tell us more. Another comment has a link to a news article that says this Bosch machine costs 15.000€ with cartridges costing 50-100€. The Bosch machine has a faster response (2.5hr), but lower overall throughput. How much does the ThermoFischer sequencer cost? Is it affordable enough that every hospital just buys one and becomes a regional testing lab? How much specialized training does it need? (in every major city…
This is not rapid, only 10 tests/day, whilst the current overly slow sequencers can do 200/day. The accuracy of 5% is also worse than other faster sequencers of 3%. And compare that to modern ThermalFischer parallel PCR sequencers, which operate in realtime, 25 tests in parallel, for 2.500€. That's a factor of 1000. With 10 modern sequencers per city you could test 10.000 per day, eg with drive-in. https://www.thermo…
Honest question, are you speaking from experience? We run PCRs at our company for our vaccine research and having to run them back-to-back day-in-day out, without any manual errors, is going to be super stressful for any lab. Not to mention the costs of training healthcare personnel on how to run a PCR.
Earlier quoted context omitted.
The full quote does one extra thing, it implies that buying 100+ of these machines is totally expected.
I'm not sure how they price these devices but it could make sense to compare against labs. The question is not how many tests a device can perform but how many tests you can perform for all available devices and at a price comparable to larger lab installations. Maybe 100 devices is a comparable rate there.
Earlier quoted context omitted.
You're forgetting the difference between bandwidth and latency.
The machine can only do one test at a time, so throughput = 1 / latency.