Hacker News Board Hacker News, browsed like a classic message board
Live data from Hacker News

Untitled topic

news.ycombinator.com

Post reply on HN
Print view View original

201–210 of 382 posts

Re: undefined

#201

Post by privatewindow »

nethergh0st wrote: post #158
baxtr wrote: post #2

The repeated recommendation to use a drug which has not been properly tested by the president of the most powerful nation on this planet seems inappropriate to me.

I watched all of the press conferences. He never recommended it. He said that it showed promise and he had high hopes that it would work. One day he even clearly said that it might or it might not work. This is hardly what I call a recommendation. The point was to give the American people some hope that we are on the right track to finding something that helps.

I watched them all too and he said no such thing. It doesn't matter to the HN crowd though because Orange Man Bad! He could save babies from drowning in a river and it still wouldn't matter to this lot here.

Lately, I have completely rethought the idea of what intelligence truly is. I used to think engineers were smart but I no longer do. There too many DUMB engineers on HN and in the valley.

Cue ban in 3, 2, 1...

Re: undefined

#202

Post by maxerickson »

Alex3917 wrote: post #82
HarryHirsch wrote: post #40

Earlier quoted context omitted.

We all made fun of South Africa's Thabo Mbeki when he recommended beetroot, garlic and other herbs to combat HIV. Turns out, we have no reason. It did happen here, on primetime TV.

The FDA approved emergency expanded access for inhaled nitric oxide a couple days ago, which has the same mechanism of action as garlic and beet root. There is actually a plausible mechanism of action there, and a bunch of in vitro research.

For treatment of HIV?

Other poster is apparently talking about https://en.wikipedia.org/wiki/HIV/AIDS_denialism_in_South_Af...

Re: undefined

#203

Post by tyingq »

bufferoverflow wrote: post #124

The article doesn't have absolutely any details. 1) What was the dose they took? 2) Where did they get it? 3) Was it medical-grade? 4) Did he die from it or just after taking it. Post hoc ergo propter hoc fallacy is in the title. 5) Is this man even real or is it an article designed to scare people against self medication or as a political hit piece? Chloroquine is a quite common antimalarial drug, and this article j…

The article links to this: http://bannerhealth.mediaroom.com/chloroquinephosphate

Which answers some of your questions, but not all.

For example: "A man has died and his wife is under critical care after the couple, both in their 60s, ingested chloroquine phosphate, an additive commonly used at aquariums to clean fish tanks. Within thirty minutes of ingestion, the couple experienced immediate effects requiring admittance to a nearby Banner Health hospital."

Re: undefined

#204

Post by throwaway_pdp09 »

Alex3917 wrote: post #159
throwaway_pdp09 wrote: post #151

Earlier quoted context omitted.

Post a link because I right now I have no reason to believe you.

I posted links to one of the in vitro studies here, and in the comments I posted the press release for the FDA approval: https://www.reddit.com/r/covid19stack

This goes to "COVID-19 Stack: Research and discussion on supplements and medications relating to COVID-19!

No mate, post a precise link. This one goes nowhere and I still don't believe you.

Re: undefined

#205

Post by jdminhbg »

tathougies wrote: post #76
plastic_teeth wrote: post #58

Earlier quoted context omitted.

True thing. Also people who I like like Elon Musk spoke about it https://twitter.com/elonmusk/status/1239650597906898947?s=20 On one side his voice should be heard, it may give people hope and help to move stuff On the other side, some people who don't know what balance is, might use it in the wrong way.

How are these people getting their hands on prescription drugs? Someone touting X prescription drug as a potential cure for something doesn't mean we should all go out and take it. I mean, PrEP is a treatment to prevent the AIDS virus from spreading, but it's not like someone being happy about that means you should somehow illegally procure and take a prescription drug. The double standards here are shocking.

> How are these people getting their hands on prescription drugs?

The people in this story didn't get their hands on prescription drugs, they found an aquarium chemical with a similar name.

Re: undefined

#206

Post by jdminhbg »

rblatz wrote: post #116
blhack wrote: post #70

Earlier quoted context omitted.

This is ridiculous. There has been studies and papers being written and released for MONTHS from all over the world. We’ve known about chloroquine since January. This INSISTENCE people keep having on politicizing this is infuriating and it’s going to get people killed. Stop doing this. Now is not the time for political point gathering.

So this isn’t a helpful tone. You are politicizing this, the FDA doesn’t just trust poorly done studies and common sense, this is why we didn’t approve Thalidomide when it was widely considered safe. Additionally you are responding to an article about people who took the drug to treat Covid-19. Peoples lives are at stake on both sides, a politician with no medical training should know better than to run his mouth abo…

> Additionally you are responding to an article about people who took the drug to treat Covid-19.

No, they did not. They took an aquarium cleaning chemical with a similar name.

Re: undefined

#207

Post by mattkrause »

chrisco255 wrote: post #132
mattkrause wrote: post #63

Earlier quoted context omitted.

Verbatim quote from the President: "if things don’t go as planned, it’s not going to kill anybody." Edit: Yes, I realize what he probably meant . I know how meds work. I still think he should have chosen his wording more carefully.

This news story is about a man consuming fish tank additive: https://aquariumstoredepot.com/products/chloroquine-phosphat... I'm not sure the difference between this and the dosages and chemical makeup of the actual drug being touted by Trump but I imagine anyone with a lick of sense would avoid consuming chemicals designed for fish tanks.

It's the phosphate salt vs. the sulphate one used in the human medicine (Plaquenil).

Both counterions get used in medicines, but it's tough to say in general if it matters: sometimes it makes a difference, other times it's just whatever's easier/cheaper to make.

Re: undefined

#208

Post by et2o »

eindiran wrote: post #183
ryan_j_naughton wrote: post #67

Earlier quoted context omitted.

That's an oversimplification. The amount for an overdose is only around 3X a regular dose (2g vs 600mg) In contrast, most drugs for which you overdose need to be at much higher dosage multiples compared to the prescribed dose.

There are plenty of drugs with a narrow therapeutic index (NTIs or NTIDs), some of which are available over the counter. Some extremely popular ones: lithium, valproic acid, acetaminophen, almost all anticoagulants (warfarin/heparin), almost all of the -mycin antibiotics (and a lot of other antibiotics), all of the tricylic antidepressants. See this paper for a very interesting discussion of the topic: https://www.nc…

People taking warfarin literally have serum levels measured frequently. Typically lithium and valproate too.

TCAs barely used any longer.

Acetaminophen doesn’t belong in this conversation with the other drugs.

Re: undefined

#209

Post by gowld »

pkaye wrote: post #31
humpty_drumpfty wrote: post #15

Earlier quoted context omitted.

Stop with the disinfo: "A man has died and his wife is under critical care after the couple, both in their 60s, ingested chloroquine phosphate," No uncertainty here. Trump killed this man, and possibly will have killed his wife.

Seems like the pharmacist is more liable since they should have given him the proper safe dosage.

The pharmacist at the aquarium supply store?

Re: undefined

#210

Post by Johnny555 »

Uehreka wrote: post #165
tomp wrote: post #44

Earlier quoted context omitted.

It's been tested for years (decades? it's generic) as an anti-malaria drug. Any drug can be overdosed.

It hasn’t been tested against Covid-19. Recommending (or even vaguely hinting) that people just try random drugs that the FDA has approved for other uses is not a strategy with no downside.

Maybe Chloroquine hasn't been tested, but Hydroxychloroquine+azithomycin was tested in a tiny 36 person trial in France, and I believe that's what Trump is basing his "hunch" on. He heard and thought he understood some small snippet of information.
Post reply on HN