I wasn't able to find a reliable source on short notice, but the ones I found indicate a therapeutic index of around 4-8 for chloroquine. The therapeutic index is the ratio between the dose that is effective and the lethal dose. So in this case if you take 4-8 times the dose that actually works you're in the range where it could kill you. I'd be really interested in more robust sources on this. But from the bits I've…
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#182Yeah it has to be in hospital setting
Because chloroquine can increase qtc on ekg
Can lead to cardiac arrest
You have to monitor heart rhythm n do ekg for a few days
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#183Earlier quoted context omitted.
It's been tested for years (decades? it's generic) as an anti-malaria drug. Any drug can be overdosed.
That's an oversimplification. The amount for an overdose is only around 3X a regular dose (2g vs 600mg) In contrast, most drugs for which you overdose need to be at much higher dosage multiples compared to the prescribed dose.
See this paper for a very interesting discussion of the topic: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4412688/
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#184Earlier quoted context omitted.
Do you have an exact quote from Henry II where he asks someone to murder Thomas Becket?
or an exact quote when George bush said there were WMDs in Iraq?
https://nsarchive2.gwu.edu//NSAEBB/NSAEBB80/new/doc%2012/Pre...
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#185Earlier quoted context omitted.
Do you have an exact quote from the president where he recommends that the public obtain and self medicate with chloroquine? Or have you significantly altered his statements for your own political agenda?
https://twitter.com/realDonaldTrump/status/12421203910547579... https://twitter.com/realdonaldtrump/status/12413672399007785... So everything below him explicitly telling everyone to obtain and consume chloroquine doesn't count, right? He's the goddamn president. I expect his words to be very carefully weighted.
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#186The repeated recommendation to use a drug which has not been properly tested by the president of the most powerful nation on this planet seems inappropriate to me.
http://bannerhealth.mediaroom.com/chloroquinephosphate
>A man has died and his wife is under critical care after the couple, both in their 60s, ingested chloroquine phosphate, an additive commonly used at aquariums to clean fish tanks. Within thirty minutes of ingestion, the couple experienced immediate effects requiring admittance to a nearby Banner Health hospita
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#187The article doesn't have absolutely any details. 1) What was the dose they took? 2) Where did they get it? 3) Was it medical-grade? 4) Did he die from it or just after taking it. Post hoc ergo propter hoc fallacy is in the title. 5) Is this man even real or is it an article designed to scare people against self medication or as a political hit piece? Chloroquine is a quite common antimalarial drug, and this article j…
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#188Earlier quoted context omitted.
Do you have an exact quote from the president where he recommends that the public obtain and self medicate with chloroquine? Or have you significantly altered his statements for your own political agenda?
https://twitter.com/realDonaldTrump/status/12421203910547579... https://twitter.com/realdonaldtrump/status/12413672399007785... So everything below him explicitly telling everyone to obtain and consume chloroquine doesn't count, right? He's the goddamn president. I expect his words to be very carefully weighted.
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#189The repeated recommendation to use a drug which has not been properly tested by the president of the most powerful nation on this planet seems inappropriate to me.
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#190Earlier quoted context omitted.
or an exact quote when George bush said there were WMDs in Iraq?
"The Iraqi regime has violated all of those obligations. It possesses and produces chemical and biological weapons." (October 7, 2002). https://nsarchive2.gwu.edu//NSAEBB/NSAEBB80/new/doc%2012/Pre...