Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

I disagree partly here based on personal experience with BJJ. I simply cannot summon fast-twitch muscle "burst" cardio on a full keto diet. After months of trying all kinds of workarounds, I had to carb-load with glucose pills (the kind diabetics take) the night before and pre-workout.

Long-term steady endurance massively increases though. If there's no bursting, I find that I can workout for hours on keto, it's amazing. It's kind of like the difference between regular diesel engines and gasoline+nitrous engines. Patience and focus seriously improve as well.

My limited understanding is that glycogen stores in muscles get depleted on full keto and must be replaced with some kind of carb intake, whether through excess protein-to-carb conversion or through normal carb intake, that "burst" energy simply isn't going to be there.

Example: I'm on the bottom in full mount and I know I need to burst to sweep somehow or shrimp out after bucking. Energy just wasn't there, time and time again. I could do jumping jacks forever, though.

I'd love to hear your feedback on this, like, what your protein intake is vs. fats.

> Such diets are still better than the SAD, but you'd get a similar bang for the buck in terms of satiety and healthfulness ... if you just stuck with whole foods at least 80% of the time.

Another useful benefit of Keto is that the rules are really simple.

That sticking with whole foods 80% of the time is the hard part, there is temptation everywhere, e.g. the Girlscout cookies on desks at work, free granola bars, etc etc. A decent % of our society is geared towards getting people to eat more.

Keto says "you can't eat any of that junk". Just, flat out. No points, no "a little bit of ice cream", just, no. The easy calories are not an option.

> Then the dreaded plateau appears, which can happen pretty fast on keto, esp due to the propaganda that calories don't matter.

Plateau's happen for many reasons, and a lot of them are not yet fully understood. For years there were stories of people eating below maintenance who aren't losing weight, and just recently science has learned that gut biomes can drop (increase?) their efficiency and result in a lower BMR than normal.

Of course at the end of the day, getting a 6 pack requires being hungry. There is no getting around that! (Well other than being under 24 and very physically active, but that's a very time boxes solution! ;) )

The postprandial hypoglycemic episodes are very rare in people that don't have diabetes, being most of the time a sign that the first-phase insulin action is impaired.

T2D is a disease of glucose intolerance, but diabetics actually deal with two problems ... insulin resistance, which the keto people focus most on, but they also deal with impaired insulin action, i.e. the ability of the pancreas to respond is impaired. What happens is that the first-phase insulin action is delayed such that later insulin action is exaggerated, causing the subsequent blood sugar crash.

And this is still not T1 diabetes, there are people in which insulin action is impaired before the insulin resistance sets in and it's still classified as T2D.

Keto proponents love to talk about this problem, but it's not a common phenomenon, not even in people that are overweight or pre-diabetic.

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Speaking of which the Keto diet does lead to impaired insulin action, coupled with physiological insulin resistance — mostly due to the "glucose sparing effect", a natural phenomenon that's reversible — but this is why the ocasional treat can send your blood glucose through the roof.

When people on Keto start measuring their glucose, they are surprise to discover just how much the starchy treats can raise their blood glucose, however this effect is misleading, because you wouldn't get the sugar spike if you weren't on Keto ;-)

This is one of the reasons why endocrinologists recommend diets that are over 100 grams in carbs per day to T2 diabetics. Because a very low carb diet requires total compliance, otherwise those hyperglycemia spikes can wreak havoc.

Keto proponents don't like to admit, but high carb diets made mostly of whole plants can be even more effective in keeping blood sugar in control, in dropping HbA1C and in losing weight.

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> "I think it's the fat that most effectively satiates"

This is a myth. Fat might be more satiating per gram, but not per calorie.

If you look at the satiety index, the foods that are most satiating tend to be low in fat and many of those items are high in carbs (by keto standards). We are speaking of items like boiled potatoes, legumes or vegetables, or lean meats like chicken breast or cod. Potatoes are what you call a "high-glycemic index" food and yet boiled or baked potatoes stay on top in every satiety test.

You should be able to see for yourself actually — compare chicken breast with chicken thigh. Same animal, same kind of protein, different fat and calories amount per gram. Eat the same amount of calories on different days and see how you feel. We have a brain hardwired to seek foods high in calories and a chicken thigh is less satiating than a chicken breast simply because the former has more calories due to the fat and thus we end up liking it more.

More importantly we've got studies on the subject and high fat diets lead to less satiety and more calories being eaten versus low fat diets:

https://europepmc.org/article/med/9225171

Also see this paper on the Swedes:

https://www.researchgate.net/publication/281229072_Politiciz...

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N.b. foods like boiled eggs are satiating in spite of the fat — unless you're talking about protein and "protein leverage", fat and carbohydrates are energy macros and do not promote satiety in any way, unless you're talking about fiber.

So what promotes satiety is:

1. fiber and volume (found in whole plants)

2. protein (e.g. the "protein leverage" theory, which is still under debate, but at least we've got some evidence for it)

3. blandness

Reasons (2) and (3) are the real reasons Keto works short term. But appetite always comes back, esp in a high fat diet. When I was on Keto I used to binge eat plain full fat butter and used to eat 1 Kg of grilled fatty pork cuts in a single sitting. And I gained weight of course.

I've been on Keto before — eating whole foods is much simpler, there's no counting of carbs involved, no danger of developing a nutrient deficiency and no fearmongering ;-)

> "Keto says "you can't eat any of that junk". Just, flat out. No points, no "a little bit of ice cream", just, no. The easy calories are not an option."

This is also a recipe for getting an eating disorder. You can't stick with this mentality unless you end up thinking that carbs are poison, which is factually wrong and a very unhealthy mentality. And do you have the same mentality about fats? Those are "easy calories" too.

Sometimes it's OK to just have one cookie. If that doesn't work for you, fine, I've been there and I can understand wanting 100% compliance, but personally I feel much better since giving up on such a goal — because no, food is not poison, food is not alcohol, chronic overeating is the problem (aka energy poisoning) and chronic overeating can happen once you develop what they call "an unhealthy relationship with food".

I now naturally want whole foods, because I get to eat more volume and it keeps me full for longer. Once I got the taste of it, I don't need to fear food categories in order to stay on path.

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> "For years there were stories of people eating below maintenance who aren't losing weight"

There's no such thing. People that eat below maintenance and not losing weight are either:

(1) underestimating their calories intake or

(2) have overestimated their maintenance requirements

If you're not losing weight, then by definition you're not eating below maintenance. And note that it is true that some medical conditions, like hypothyroidism, lead to a lowered metabolic rate (the thyroid is responsible for raising your body temperature for example), but in all cases we aren't talking about more than 200 - 300 kcal. So in order to lose weight, even people suffering from hypothyroidism can simply eat 2-300 kcal less — it's harder but it can be done. And if you claim a bigger penalty than that, you start breaking the laws of physics.

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> "just recently science has learned that gut biomes can drop (increase?) their efficiency and result in a lower BMR than normal"

No, that did not happen. The research you're talking about was inconclusive and it was done IN MICE.

There are indications that the health of the microbiome is important, however the associations between the _human_ microbiome and obesity are weak and don't appear to be causal.

I.e. people that are obese tend to eat a less diverse diet (less whole plants). Such people also have less diversity in their microbiome. You cannot infer from that the microbiome is what caused their obesity, the huge confounder in such associations being the diet itself.

The reason I refuse to read about keto is that pretty much all doctors and public health organizations I’ve seen recommend basically the same things: whole grains, fruits, vegetables, replace saturated fats with unsaturated if possible, low fat dairy, nuts, legumes, fish, some poultry sometimes, strictly controlled alcohol.

Until these guys start recommending something such as keto my basic assumption is that it’s either a weird fringe diet or a diet only applicable to very specific medical issues (eg seizures) that me (not a medical professional) should not try on myself.

If I go to a doctor and they ask how my diet is and I tell them I eat the stuff I listed above, I’m fairly certain they will tell me good job. If I do some extreme fringe thing, I doubt it will be their response with the same likelihood (though a few probably like it).

This is just my personal opinion.