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Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

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Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#261
post #61

Earlier quoted context omitted.

I am having trouble agreeing with the statement that "...your body will convert the protein to glucose..." Could you elaborate on that logic?

While several people refer to gluconeogenesis, to the best of my knowledge we _can_ make glucose from protein, but rarely do in practice. I have yet to see anyone convincingly show that we do. Also check out diet doctors take on it which refers to actual studies. "Does protein adversely affect blood sugar?" https://www.dietdoctor.com/low-carb/protein

Anyone on a zero/near zero carb diet should be proof enough. We can't survive with _no_ glucose.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#262

Earlier quoted context omitted.

> Also you can't go full keto if you also want weight training, imo. You absolutely can, and people are doing it just fine. Check out Metabolic Autophagy: https://www.amazon.com/Metabolic-Autophagy-Intermittent-Resi...

Yep working fine here on ‘full’ keto (not sure what other kind there is) Depends what you want from your weight training. I enjoy it but I’m not trying to get massive gains.

Can you detail on this and what type of training you do? Also what type of gains you experienced?

Sure you can do full keto and weight train but I am interested in the gains versus low carb / medium carb diets.

As for me, I'm on a low carb diet mostly, although I do enjoy some days of high carb as well.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#263

A lot of folks here are using the term "intermittent fasting". This is a term that can make people struggling with eating disorders kinda lose their minds. May suggest to replace this term with what's probably a better way of saying it anyway, because it's more accurate to what people are really doing when they say IF: Call it "time-restricted eating" . You're eating the food you eat for a day in a smaller window. No…

> This is a term that can make people struggling with eating disorders kinda lose their minds.

Maybe focus on the actual thing and not policing speech?

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#264

Earlier quoted context omitted.

Your last paragraph is just unbelievably flat-out wrong. Maybe you didn't suffer from keto flu, but it can last for a couple weeks to a couple months (my case) and has zero to do with dehydration. You're literally retraining your body to efficiently burn stored body fat when it never had to much before. This takes time. The idea that it happens in days is laughable, as is the idea that your microbiome adjusts that qu…

No, you probably suffered from nutrient deficiencies, symptoms that went away once you diversified. A total guess of what happened to you, but what's not a guess is about the adaptation taking months and being about anything more than dehydration or nutrient deficiency being total bullshit.

Cutting out high-GI foods doesn't produce nutrient deficiencies, since they're generally calorie-dense but low in vitamins etc. If anything, the fact that you're getting more meat and veggies to make up for it increases your nutrient diversity, from day one. So again, you're completely wrong.

As for adaptation taking merely days, what's your source for that? The common wisdom and community consensus that you'll read anywhere is that it takes roughly 2 weeks to 2 months to adjust. You're the one claiming this is wrong. So what exactly is your proof here?

Look, I'm glad it wasn't a problem for you. But claiming that therefore it isn't for others, just doesn't hold water.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#265

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As it turns out, insulin resistance, like that associated with type-2 diabetes, is also related to inflammation (apparently due to cytokines: https://www.webmd.com/diabetes/inflammation-and-diabetes ), which in turn is correlated with heart disease. As I understand it (disclaimer: I'm not a doctor), the inflammation results in damage to the blood vessels, which your body repairs by using cholesterol, among other thin…

Dietary cholesterol is very directly correlated with blood cholesterol levels. You can feed someone cholesterol and directly watch their levels spike. But your body will clear it if you give it time which is why your fasting cholesterol may not show this if you have naturally low levels. But during that window if time that cholesterol is active in your blood it's not doing you any favors. This is why heart attacks ve…

> Dietary cholesterol is very directly correlated with blood cholesterol levels. You can feed someone cholesterol and directly watch their levels spike.

This is not true. In fact, I doubt dietary cholesterol has any affects on blood cholesterol.

Source: eating >= 6 full eggs daily for years; have 8 pack; blood work always on point.

And also I've done the same exact thing you mention and it didn't affect my blood levels at all.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#266
post #92

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I always thought it wasn't recommended to stay in ketosis for more than 2 weeks at a time?

I cannot say that it isn't recommended, because recommendations are quite diverse. But I haven't seen that recommendation before. Orthodox nutritionists would definitely advice against ketosis, potentially they may be fine with fasting-induced ketosis every once in a while (depends a bit on how they were trained). People who embrace a low-carb ketosis-inducing diet (aka "Keto diet") or embrace multi-day fasting don't…

I believe that was the Atkins recommendation

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#267
post #245

Earlier quoted context omitted.

GNG increases when in ketosis, but is still capped because ketones regulate the GNG process. That is the effect which was observed here. It says it right there in the synopsis: "Glucose concentration was lower (4·09 (sem 0·10) v. 4·89 (sem 0·06) mmol/l, P β-hydroxybutyrate is a ketone body. Note that this contradicts your statements that GNG will kick you out of ketosis. It absolutely will not. To repeat: GNG is cons…

>Note that this contradicts your statements that GNG will kick you out of ketosis. It absolutely will not. Its really simple, eat nothing but chicken and/or turkey (high protein, low fat, no carb). You will not become keto adapted or fat adapted. Alternatively enter into nutritional (dietary) ketosis with a high fat diet, then switch to chicken and/or turkey only (high protein, low fat, no carb) you will not remain i…

I'm not aware of any dietary fat requirement to enter or maintain ketosis. I've talked to others that mention a protein/fat ratio but I've not see any literature about it. Citation appreciated.

A low carb and low fat diet is unhealthy for lean people because fat/fatty acids/etc is required for a whole lot of synthesis.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#268
post #87

I still don't understand the tech bro fascination with disordered eating.

Many of us suffer from autism or anxiety or some other mental issue and hope to cure it with some strange diet. That's why despite being some of the most intelligent people on the internet people here will latch on to some singular model of human metabolism that's being promoted by the Russians or the Chinese right now (kidding, but only partly) and use it to justify a new "experiment". Imposter syndrome fits in ther…

What the hell did I just read.

Intermittent fasting works. Talk to people that can show you results. Enough with the "theory".

I've heard many theories from obese people and it's always bullshit. Everyone can find far fetched theories for anything on this planet. That's why results talk. You know how they say "money talks"? Same here: results talk.

I, on the other hand, can tell you what works 100%, based on results (like 8% bodyfat, in very good shape):

Eat clean food, exercise daily, eat in 6-8 hours per day. Don't eat too many calories in total.

Do this for some time and I guarantee you will see effects. It only takes will and it's not rocket science.

Most bodybuilders that I see are people that are just, you know, dumb. And they can do it. So I promise you it's not complicated or anything. So I don't know what's stopping people from doing it.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#269
post #260

Earlier quoted context omitted.

> If you have never entered ketosis and experienced your brain running on ketones, I would suggest you experiment for yourself. I would say a minimum 2-3 months which should be enough time for your microbiome to change and your body/brain to adapt primarily running on ketones. I've been on Keto for about 8 months (before giving up), measuring my blood ketones and being in deep ketosis between meals (over 2 mmol/L). I…

I actually agree with most all of your posts. The one big difference, though, in my opinion, is that when adapted to a very low carbohydrate diet, it's actually easier for me to not eat. That's it. To me, it's the lone advantage. It's not about the palatability of the low-carb meals. It's that I just seem to be less hungry. I can skip a meal and it's no big deal. When I'm higher carb, missing a meal takes a way bigge…

When you state "very low carbohydrate diet" - what do you mean? Do you mean you're actively avoiding fruits and vegetables, oats, nuts, etc? Or are you avoiding processed foods and the carbs that go along with that? The "carbs are the devil" argument is a huge misconception with people.

You mentioned that it's easier for you to not eat on a very low carbohydrate diet. My main eating regimen is two feeding periods that are generally between 12:00P and 8:00P. My diet is mainly plant based, so very high in unprocessed carbohydrates - and I do still eat fish and am also not opposed to eggs from time to time. I have no problem not eating. If I don't eat at all until the early evening I am generally never hungry.

So I'm genuinely interested in what you mean by "high carb". Processed carbs and satiety don't go hand in hand, but a "high carb" intake of whole foods is not remotely the same.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#270

Earlier quoted context omitted.

Meat raises insulin levels significantly. A steak spikes your insulin harder than a plate of spaghetti.

They're pretty close according to https://en.wikipedia.org/wiki/Insulin_index "White pasta" 40 ±5 vs. "Beef" 51 ±16

1) That's per 250 kcal. A plate of pasta has significantly fewer calories than a plate of steak. Sauces on either can alter this, but they'll likely have their own indices to pay attention to. 2) The low ends are equal. The high ends are off by a factor of 1.5.

I think that the real question is "What will happen to my insulin if I eat a meal of pasta vs, a meal of steak?". To that, I think that the steak will in fact spike your insulin much higher than the pasta.

That said the beef has a higher satiety score (by almost exactly the same ratio as the high end insulin ratio).

Again, sauces, what your body needs right now, what you'll eat for your next meal,... lots of things can alter the overall health perspective.

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