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Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

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Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#251
post #37

Earlier quoted context omitted.

> If you have never entered ketosis and experienced your brain running on ketones, I would suggest you experiment for yourself. How do you do that? If the low-carb diet isn't enough, what is?

Low carb is generally considered to be under 100g carbs/day. Ketosis requires under 20g carbs/day.

Ketosis is a normal supplemental metabolic state that the body enters in between meals to various degrees. There's no hard black/white macro requirement.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#252

Earlier quoted context omitted.

isn't ketosis very subtle to maintain otherwise it can harmful effects ?

People confuse it with ketoacidosis, which is very dangerous. Ketosis is benign.

Had a doctor tell me ketosis was very dangerous (she was confusing it with ketoacidosis). I couldn't help but completely stop listening to her after that.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#253

Earlier quoted context omitted.

People confuse it with ketoacidosis, which is very dangerous. Ketosis is benign.

The biggest issue with ketogenic diets is elevated level of cholesterol, which is generally considered harmful, though there are different views on this topic.

The issue is the "generally considered harmful." High-fat low-carb diets tend to improve triglyceride profiles. Dietary cholesterol is not the same thing as blood cholesterol levels.

Anecdotally, my father and I discovered separately, in bloodwork unrelated to our individual diets, that a HFLC diet significantly decreased LDL and increased HDL.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#254

I don't really understand the briefing here; so would taking exogenous ketones also help mirror the beneficial effects of ketosis seen in this study? They did mention feeding their participants exogenous ketones but didn't say anything about those peoples' carb/fat ratios. I'm all for jumping on the high fat/low carb diet; however, I love getting all my polyphenols and other beneficial compounds that are part and par…

There are studies looking at this question.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#255
post #214

Earlier quoted context omitted.

Full-on keto may not be worth it, but I would highly suggest removing most carbs from your diet (<= 30g per meal). You'll feel completely different within 5 days. This is especially noticeable after the age of 30. I have no scientific backing or research for this, but I've had a number of friends and family make this small change and every single one has not gone back. It's not even that difficult if you already have…

Yes you will feel like you have no energy during workouts. The primary fuel for muscles is glycogen. Cells use glucose by default. And fats are 9 cal/g, so they’re so easy to overeat. I don’t understand why limiting carbs makes any sense.

> I don’t understand why limiting carbs makes any sense.

Then why go around saying things like:

> Yes you will feel like you have no energy during workouts. The primary fuel for muscles is glycogen. Cells use glucose by default. And fats are 9 cal/g, so they’re so easy to overeat.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#256
post #102

The title is terrible, it should read ketosis/ketones may prevent, reverse age-related effects within the brain. "Low carb" as the title currently reads does not necessarily result in ketosis and your body/brain running on ketones, which appears to be the scope of this study. There is more to dietary ketosis than low carb, just as an example carnivore or paleo diets are low carb, but those will generally not result i…

How does working out at a high intensity work when in a state of Ketosis? I lift weights and/or do HIIT 5x per week and occasionally add running on top of that. I've always been weary of going low carb or trying a keto diet because I feel like I just won't have the energy to continue my training regimen at its current intensity. The typical advice is to eat your allocated carbs 1-2 hours prior to your workout, howeve…

I do similar exercise and when I started keto 8 months ago I had a dip in performance for about 3 weeks.

I do a similar set of exercises on the same day/time every week and it ends with 30 seconds of burpees.

Prior to going on keto I was doing 16 burpees in that 30 seconds. After the first week I was down to twelve. After a couple more weeks I was back to 16 - and two weeks after that I was on 17. I’m now on 18.

I’ve gone from 103kg to 88kg in that time, so it seems likely the weight loss has been a (or the) factor in the improved performance.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#257
post #245

Earlier quoted context omitted.

>excess protein is not converted to fat via GNG, but is used for protein synthesis, and increases lean body mass. >In conclusion, after a high-protein diet, GNG was increased... https://www.cambridge.org/core/journals/british-journal-of-n...

GNG increases when in ketosis, but is still capped because ketones regulate the GNG process. That is the effect which was observed here. It says it right there in the synopsis: "Glucose concentration was lower (4·09 (sem 0·10) v. 4·89 (sem 0·06) mmol/l, P β-hydroxybutyrate is a ketone body. Note that this contradicts your statements that GNG will kick you out of ketosis. It absolutely will not. To repeat: GNG is cons…

>Note that this contradicts your statements that GNG will kick you out of ketosis. It absolutely will not.

Its really simple, eat nothing but chicken and/or turkey (high protein, low fat, no carb). You will not become keto adapted or fat adapted.

Alternatively enter into nutritional (dietary) ketosis with a high fat diet, then switch to chicken and/or turkey only (high protein, low fat, no carb) you will not remain in ketosis.

Do you disagree with that? Have you seen any study that shows fat/protein ratios are immaterial to nutritional ketosis?

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#258

How about weight training and low carb and sometimes IF? Would weight training prevent age related effects within the brain? Also you can't go full keto if you also want weight training, imo.

> Also you can't go full keto if you also want weight training, imo. You absolutely can, and people are doing it just fine. Check out Metabolic Autophagy: https://www.amazon.com/Metabolic-Autophagy-Intermittent-Resi...

Yep working fine here on ‘full’ keto (not sure what other kind there is) Depends what you want from your weight training. I enjoy it but I’m not trying to get massive gains.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#259

The title is terrible, it should read ketosis/ketones may prevent, reverse age-related effects within the brain. "Low carb" as the title currently reads does not necessarily result in ketosis and your body/brain running on ketones, which appears to be the scope of this study. There is more to dietary ketosis than low carb, just as an example carnivore or paleo diets are low carb, but those will generally not result i…

> If you have never entered ketosis and experienced your brain running on ketones, I would suggest you experiment for yourself. I would say a minimum 2-3 months which should be enough time for your microbiome to change and your body/brain to adapt primarily running on ketones. I've been on Keto for about 8 months (before giving up), measuring my blood ketones and being in deep ketosis between meals (over 2 mmol/L). I…

You must not be a very perceptive individual.

Re: Study: Low Carb Diet May Prevent, Reverse Age-Related Effects Within the Brain

#260

The title is terrible, it should read ketosis/ketones may prevent, reverse age-related effects within the brain. "Low carb" as the title currently reads does not necessarily result in ketosis and your body/brain running on ketones, which appears to be the scope of this study. There is more to dietary ketosis than low carb, just as an example carnivore or paleo diets are low carb, but those will generally not result i…

> If you have never entered ketosis and experienced your brain running on ketones, I would suggest you experiment for yourself. I would say a minimum 2-3 months which should be enough time for your microbiome to change and your body/brain to adapt primarily running on ketones. I've been on Keto for about 8 months (before giving up), measuring my blood ketones and being in deep ketosis between meals (over 2 mmol/L). I…

I actually agree with most all of your posts. The one big difference, though, in my opinion, is that when adapted to a very low carbohydrate diet, it's actually easier for me to not eat. That's it. To me, it's the lone advantage. It's not about the palatability of the low-carb meals. It's that I just seem to be less hungry. I can skip a meal and it's no big deal. When I'm higher carb, missing a meal takes a way bigger toll.

One other thing I'd offer -- for long endurance activities at higher heart rates (e.g., cycling in zone 4 for more than an hour), you absolutely have to supplement with carbs. You can go a long time in Zone 3 on a low carb diet, but as exertion increases, you burn through those sugar stores and bonk. I've tested this repeatedly. In case it's helpful to others, you can consume quite a bit of sugar on a hard ride and be right back in ketosis hours later as your muscles take up the glucose first.

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