141–150 of 298 posts
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I am bookmarking this comment for the time after self-driving cars have become universally available.
given the longevity of webservices online I bet HN is gone before that day happens
I don't know what your over-under on self-driving cars being prevalent is, so I don't know if this supports your point or not.
From the paper: > If the neuroinvasion of SARS-CoV-2 does take a part in the development of respiratory failure in COVID-19 patients, the precaution with masks will absolutely be the most effective measure to protect against the possible entry of the virus into the CNS. It may also be expected that the symptoms of the patients infected via facal-oral or conjunctival route will be lighter than those infected intranasa…
Yes, only a N95 or better mask would protect you from incoming, as opposed to outgoing, viruses, and these masks are both impractical for everyday wear and need to be conserved for public health users.
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This suggests an advantage to purposeful infection by oral/eye rather than accidental by intranasal. It'll be interesting to see what the case fatality rate is when segmented by infection route.
It's been suggested to me, in addition to hand washing, to use soap to rinse a bit of my nostrils. Not sure if it makes any difference at all, but I've been doing it on the off-chance.
Earlier quoted context omitted.
Given there's no herd immunity, and the virulance of the strain, estimates are 40-70% of the population will contract the virus within a year 0.2% of 40% of the US Population is 260,000 deaths within a year[1] "it's just the flu" greatly underappreciates just how deadly influenza actually is If the mortality rate is more in the 2%+ range, we're looking at millions of deaths in the US alone. [1] https://www.wolframalp…
I've seen very different estimates. I'm gonna go off on a limb and say that there's probably more misinformation out there than real information. People should remain calm, take [0]reasonable precautions, and make decisions based on the latest information from credible sources such as the [1]CDC - rather than the media. [0] https://twitter.com/eugenegu/status/1235247642814214145 [1] https://www.cdc.gov/coronavirus/20…
https://www.wsj.com/articles/how-many-people-might-one-perso...
> “I think it is likely we’ll see a global pandemic,” said Marc Lipsitch, a professor of epidemiology at Harvard T.H. Chan School of Public Health. “If a pandemic happens, 40% to 70% of people world-wide are likely to be infected in the coming year. What proportion of those will be symptomatic, I can’t give a good number.”
From the paper: > If the neuroinvasion of SARS-CoV-2 does take a part in the development of respiratory failure in COVID-19 patients, the precaution with masks will absolutely be the most effective measure to protect against the possible entry of the virus into the CNS. It may also be expected that the symptoms of the patients infected via facal-oral or conjunctival route will be lighter than those infected intranasa…
This is super scary. Before I read this I was happily thinking hey it's no worse than flu. Now... I'm wishing I didn't live in a huge city riding the subway daily.
As of yesterday, China, a country of 1.4B, had 80,000 cases and 3,000 dead.
Last year, the US had 36M infected with the flu and 34,000 died.[1]
Are you panicking about the flu?
Earlier quoted context omitted.
Why is it easier to get to the brain from the nose compares to the mouth or eyes?
https://en.wikipedia.org/wiki/Olfactory_bulb . however: Yan-Chao Li [etal.] ABSTRACT Swine hemagglutinating encephalomyelitis virus (HEV) has been shown to have a capability to propagate via neural circuits to the central nervous system after pe- ripheral inoculation, resulting in acute deadly encepha- lomyelitis in natural host piglets as well as in experimental younger rodents. This study has system- atically exami…
From the paper: > If the neuroinvasion of SARS-CoV-2 does take a part in the development of respiratory failure in COVID-19 patients, the precaution with masks will absolutely be the most effective measure to protect against the possible entry of the virus into the CNS. It may also be expected that the symptoms of the patients infected via facal-oral or conjunctival route will be lighter than those infected intranasa…
This is super scary. Before I read this I was happily thinking hey it's no worse than flu. Now... I'm wishing I didn't live in a huge city riding the subway daily.
As a side observation: most reporting seems rather binary, i.e. you either die or survive, period. What interests me the most, however, is how often survival means full recovery, especially now that the nervous system comes up. Are there any long term effects? Should one generally expect to come out of it worse, the same, or stronger? I'm much less afraid to die from this than to end up with chronic respiratory and/o…
I'm not sure exactly how they evaluate risk, but they probably estimate the error based on populations where very few people are studied (probably most people below 50), so it's likely if you're below 50 the chances are actually lower, I'm not sure.
Risk factors for immune disorders and car accidents are probably similar if I were to conjecture (just in: sick people tend to die), so most people on this subreddit will just get the fever. 15% of people don't even present with a fever, so it seems like the immune system can typically fight it off.
There's other literature out there saying ACE2 is ubiquitously expressed (including brain) - so that means one of two things: People saying it's expressed everywhere are wrong, or SARS-COV-2 requires more than ACE2 for infection. There are papers saying that transfecting cell lines with ACE2 doesn't always render the cells susceptible, so it's probably a good idea to consider the requirement for a co-receptor.
Like anything, the true answer probably lies in between all these possibilities.
From the paper: > If the neuroinvasion of SARS-CoV-2 does take a part in the development of respiratory failure in COVID-19 patients, the precaution with masks will absolutely be the most effective measure to protect against the possible entry of the virus into the CNS. It may also be expected that the symptoms of the patients infected via facal-oral or conjunctival route will be lighter than those infected intranasa…