51–60 of 298 posts
I see a lot of "may", "possible", "if", ... Is this how people typically write a paper to Medical Virology?
I wont assume that (I am software engg.)
I see where you are coming from. Here is my perspective, think of this like a outage of your service. No one has exact answers so team starts to dive in and starts sharing what they find.
These findings mostly prune the "solution space" of the problem.
Earlier quoted context omitted.
Yes, only a N95 or better mask would protect you from incoming, as opposed to outgoing, viruses, and these masks are both impractical for everyday wear and need to be conserved for public health users.
I think there's a legitimate question here. Intuitively, if a non-N95 mask only stops 25% or 50% of incoming viruses, that still seems helpful? It's worth noting that in countries where wearing masks is normalized, making sure the general public can get some is a top priority.
When you exhale it is more wet and the moisture causes the barrier to catch more of the airborne particles. The barrier also catches any more-solid material that would otherwise land elsewhere, providing a mechanism for the particle to spread.
This means the net gain for wearing them to keep from catching the disease is relatively small compared to the gain by wearing them to prevent the spread if you may have been exposed.
Not a biologist, but reading the paper, the chain of reasoning appears to be summarized in this section: > Taken together, the neuroinvasive propensity has been demonstrated as a common feature of CoVs. In light of the high similarity between SARS-CoV and SARS-CoV2, it is quite likely that SARS-CoV-2 also possesses a similar potential. Based on an epidemiological survey on COVID-19, the median time from the first sym…
The olfactory receptors (nerves that smell) are among the most exposed nerves of the body, and IIRC they are single cells stretching from the mucus membrane in your nose all the way to the brain. And because smell is such an evolutionary ancient function, the relevant brain region is really close to the centre of the brain (and brainstem).
So it's really just two hops from the outside world to the command post of your autonomous nervous system (i. e. breathing)
I see a lot of "may", "possible", "if", ... Is this how people typically write a paper to Medical Virology?
Earlier quoted context omitted.
Yes, only a N95 or better mask would protect you from incoming, as opposed to outgoing, viruses, and these masks are both impractical for everyday wear and need to be conserved for public health users.
I'm not sure I would call them impractical for everyday wear. I wear N95 masks when commuting during active wildfires. The news always says not to wear them because you won't put them on properly, but it's really not that hard to ensure the fitment is correct. It's not like the construction workers that wear them occupationally are rocket scientists. My partner is more vulnerable to respiratory problems and has alway…
From the paper: > If the neuroinvasion of SARS-CoV-2 does take a part in the development of respiratory failure in COVID-19 patients, the precaution with masks will absolutely be the most effective measure to protect against the possible entry of the virus into the CNS. It may also be expected that the symptoms of the patients infected via facal-oral or conjunctival route will be lighter than those infected intranasa…
Not a biologist, but reading the paper, the chain of reasoning appears to be summarized in this section: > Taken together, the neuroinvasive propensity has been demonstrated as a common feature of CoVs. In light of the high similarity between SARS-CoV and SARS-CoV2, it is quite likely that SARS-CoV-2 also possesses a similar potential. Based on an epidemiological survey on COVID-19, the median time from the first sym…
You are now breathing manually ... forever.
From the paper: > If the neuroinvasion of SARS-CoV-2 does take a part in the development of respiratory failure in COVID-19 patients, the precaution with masks will absolutely be the most effective measure to protect against the possible entry of the virus into the CNS. It may also be expected that the symptoms of the patients infected via facal-oral or conjunctival route will be lighter than those infected intranasa…
Yes, only a N95 or better mask would protect you from incoming, as opposed to outgoing, viruses, and these masks are both impractical for everyday wear and need to be conserved for public health users.
Please somebody show me data that proves otherwise, I'm totally open to it. (Note: I'm not saying I want you to post opinions from people in authority, I'm saying I want to see data)
From the paper: > If the neuroinvasion of SARS-CoV-2 does take a part in the development of respiratory failure in COVID-19 patients, the precaution with masks will absolutely be the most effective measure to protect against the possible entry of the virus into the CNS. It may also be expected that the symptoms of the patients infected via facal-oral or conjunctival route will be lighter than those infected intranasa…
This is super scary. Before I read this I was happily thinking hey it's no worse than flu. Now... I'm wishing I didn't live in a huge city riding the subway daily.