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Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

hopkinsmedicine.org

51–60 of 98 posts

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#51
post #35
post #25

Earlier quoted context omitted.

I myself have tinnitus as well. Curious if you have tried the Notched music approach ( https://scholar.google.com/scholar?cites=1630358227661185623... ) or the Neighbouring Tones ( https://scholar.google.com/scholar?cites=1037530052919306668... ) approach. Apparently both of the have had some kind of success in treating tinnitus. Unfortunately for me, they work better for "lower" frequencies. My tinnitus is around 10…

I’m affected as well, noise damage. Had seen the papers coming out a while ago and desperately waiting for something that becomes available “for the masses”. Do you know of any existing self-treatment (e.g. an app that applies a notch filter on acting as a Spotify client) or do you happen to have any reference to more specific treatments that might be available on the market?

Not a cure, but Chroma Doze available from fdroid is a fantastic noise generator that lets you easily create new combinations of static noise.

Sometimes when my tinnitus gets a bit worse I find I can hear it over the noise generator. Changing the pattern hides it again immediately for me.

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#52
post #30

I'll be interested to see how this pans out. I have significant hearing loss in both ears from infections as a baby, and the doctors always said it was because the hairs in my cochlea are dead. I was denied a few opportunities when I was younger due to my hearing, and I still can't hear most higher frequency sounds (whistles, some cymbals, smoke detectors, fire alarms...etc). It would be nice to be able to hear what…

I'm interested to hear more.

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#53
post #42
post #27

Earlier quoted context omitted.

YMMV (from Reddit thread): --- Strong temporary relief from tinnitus: Place the palms of your hands over your ears with fingers resting gently on the back of your head. Your middle fingers should point toward one another just above the base of your skull. Place your index fingers on top of you middle fingers and snap them (the index fingers) onto the skull making a loud, drumming noise. Repeat 40-50 times. Some peopl…

Have tried this a couple of times with zero relief unfortunately. I have conductive hearing loss due to otosclerosis (plaque buildup on stapes) so that might be why it doesn't work for me.

Same here. My hearing is getting worse and I might have an operation in a few month. Luckily only one side is affected (for now, chances are not good it remains that way)

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#54
post #3

My wife has premature hearing loss of an unknown cause. Doctor kind of shrugged when asked what could be done about it. This was some 15 years ago. I'll push her to make an appointment with a doc again to see if something new has been discovered.

Since most of us are required to work cacophonous open offices and have to drown out the insanity with hearing-destroying headphones just to concentrate well enough to get our jobs done, this is (I guess) good news for everybody.

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#55
post #46

Earlier quoted context omitted.

Yours is worse than mine but same root cause and probably exacerbated by power tools and loud music (and loud music at a bar called power tools) later on. There's a huge dip in the middle of my hearing range so I can hear the clink-clink-clink of pint glasses in a pub but people speaking to me over it is a struggle.

Yeah, hearing people over background noise is probably the thing that I struggle with the most. It's been a pretty big social hindrance, especially when I was in college. In crowded social areas like bars and restaurants it's very difficult for me to understand what people are saying. As a result, I ended up being the weird guy just sitting there not saying anything all night because I was unable to carry on a conver…

I am going to venture and say this is not related to the ear apparatus, but in perception processing. I believe this type of deficit has been associated with ADHD, and other neurodevelopmental disorders/variations.

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#56
post #46

Earlier quoted context omitted.

Yeah, hearing people over background noise is probably the thing that I struggle with the most. It's been a pretty big social hindrance, especially when I was in college. In crowded social areas like bars and restaurants it's very difficult for me to understand what people are saying. As a result, I ended up being the weird guy just sitting there not saying anything all night because I was unable to carry on a conver…

I am going to venture and say this is not related to the ear apparatus, but in perception processing. I believe this type of deficit has been associated with ADHD, and other neurodevelopmental disorders/variations.

As someone with attention issues, I've wondered if this contributes to my issues in loud environments. I feel like it's a blend of "your brain is being overwhelmed" and "this place actually sucks for everyone".

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#57

Earlier quoted context omitted.

I am going to venture and say this is not related to the ear apparatus, but in perception processing. I believe this type of deficit has been associated with ADHD, and other neurodevelopmental disorders/variations.

As someone with attention issues, I've wondered if this contributes to my issues in loud environments. I feel like it's a blend of "your brain is being overwhelmed" and "this place actually sucks for everyone".

Yes. Hearing voices in a loud environment means turning the gain down on other sounds and amping the gain on the voices, but if your attention system can less efficiently choose or if your top-down inhibitory systems are inefficient, then comprehension will be difficult.

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#58
post #3

My wife has premature hearing loss of an unknown cause. Doctor kind of shrugged when asked what could be done about it. This was some 15 years ago. I'll push her to make an appointment with a doc again to see if something new has been discovered.

My dad has severe hearing loss (hearing aids, etc.) but we made an interesting discovery: bone-conduction headphones bypass the portion of his ear that's damaged. When he first put them on he literally said: "That's better than I've heard anything sound in a decade". YMMV but it might be something useful to try with your wife.

Do you have a source for any good bone conduction headphones? I have a damaged eardrum that stops me hearing low frequencies.

Recently tried a demonstration at SF's Exploratorium which involved biting a metal bar, and the result was incredible!

Most bone conduction headphones I find when searching (eg AfterShokz) appear to rest against the bones around the ear, so I'm not sure if they're as effective.

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#59
post #46

Earlier quoted context omitted.

Yeah, hearing people over background noise is probably the thing that I struggle with the most. It's been a pretty big social hindrance, especially when I was in college. In crowded social areas like bars and restaurants it's very difficult for me to understand what people are saying. As a result, I ended up being the weird guy just sitting there not saying anything all night because I was unable to carry on a conver…

I am going to venture and say this is not related to the ear apparatus, but in perception processing. I believe this type of deficit has been associated with ADHD, and other neurodevelopmental disorders/variations.

It's both. Google on "hidden hearing loss", "cochlear synaptopathy", "central processing disorders", "auditory scene analysis" and "the cocktail party problem".

Re: Proteins That May Restore Damaged Sound-Detecting Cells in the Ear

#60

I was hoping to read that it might also help people like myself who suffer from tinnitus. Sadly, no. Still, if it can restore hearing to the deaf, this is a good thing.

> I was hoping to read that it might also help people like myself who suffer from tinnitus. Sadly, no.

It depends, I have tinnitus and high-frequency hearing loss. It's not at the point where I need hearing aids, but anecdotally a friend of mine who got hearing aids reported that his tinnitus goes away when using them.

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