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Inflammation might be the root of preventable disease

harvardmagazine.com

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Re: Inflammation might be the root of preventable disease

#181

Post by naasking »

mhkool wrote: post #169
naasking wrote: post #167

Earlier quoted context omitted.

> inflammation is the description of what is happening (ie, symptom) not the "cause" If you chemically turn off inflammation and the negative downstream effects disappear, then inflammation is arguably a cause of those negative effects. Inflammation is supposed to be a healthy response to various conditions, but that isn't always the case, so when it's causing negative effects it becomes a pathology and arguably a ca…

The term "root cause" was not invented for nothing. One should always try to find the root cause since if you do not find it you are fighting a symptom instead of a cause. There is a huge amount of research about what causes inflammation so it is correct to say that inflammation is a symptom not a cause.

> There is a huge amount of research about what causes inflammation so it is correct to say that inflammation is a symptom not a cause.

It is not necessarily just a symptom, that's the point. So no, it's not necessarily correct because sometimes inflammation is exactly the cause.

Re: Inflammation might be the root of preventable disease

#182

Post by ZeroFries »

Roaexus wrote: post #175

Eating a whole foods planet based diet can reverse diabetes and significantly reduce inflammation. I didn't believe this until I had a dear friend pass away from a heart attack at 33. This forced me into getting my blood work done. I was astonished how bad my numbers looked across the board even though I was skinny. By eating a planet based diet all my numbers have normalized. I eat and sleep better. My energy has in…

Neptune is my favourite snack.

Re: Inflammation might be the root of preventable disease

#183

Post by magnamerc »

manmal wrote: post #133
rossdavidh wrote: post #63

My prediction: 1) reducing chronic inflammation by, for example, exercise or eating better food, is proven to have good health effects 2) pharmaceutical companies try to make that into a pill 3) dang, the benefits of the pill are not nearly as big as if you exercise and eat better food, and not nearly as big as our early trials of the drug indicated they would be 4) we must need a different kind of pill

Resveratrol was such a pill/fad, with some companies going belly up eventually.

It's still an interesting compound because of it's role in regulating processes within mTOR, however getting the Resveratrol to where you need it (bioavailability) is an almost insurmountable problem.

Re: Inflammation might be the root of preventable disease

#184

Post by hjk05 »

braink wrote: post #124
rossdavidh wrote: post #63

My prediction: 1) reducing chronic inflammation by, for example, exercise or eating better food, is proven to have good health effects 2) pharmaceutical companies try to make that into a pill 3) dang, the benefits of the pill are not nearly as big as if you exercise and eat better food, and not nearly as big as our early trials of the drug indicated they would be 4) we must need a different kind of pill

Bottom line: pharma sells pills to make money; they don't make money off of healthy people who don't take their pills. So long as we link the health industry to making profit, we are prioritizing profits over health.

It’s a very limited view on any industry to think that profits and greater good cannot coexist. You say the pharma industry just makes pills so they can extract profits. The researchers at those companies who dedicate their lives in persuit of treatments for the benefits of patient would say we only make money so we can make new treatments.

That’s just semantics in the end. But it’s foolish to think that just because some endeavor is profitable is must be immoral.

Re: Inflammation might be the root of preventable disease

#185

Post by shloosh »

ixtli wrote: post #66
rossdavidh wrote: post #63

My prediction: 1) reducing chronic inflammation by, for example, exercise or eating better food, is proven to have good health effects 2) pharmaceutical companies try to make that into a pill 3) dang, the benefits of the pill are not nearly as big as if you exercise and eat better food, and not nearly as big as our early trials of the drug indicated they would be 4) we must need a different kind of pill

Yup! I would also predict this. You simply can’t engineer your way out of needing better living conditions.

Well, I would argue that actually you can, but it is extremely difficult and we aren't at that level technologically yet. Currently, the best solution for many health conditions is to optimize sleep, diet, and exercise. We will probably be uploaded into machines before a pill can replace any one of those functions.

Re: Inflammation might be the root of preventable disease

#187

Post by artemisyna »

RobertRoberts wrote: post #78
artemisyna wrote: post #40

Earlier quoted context omitted.

I think what the other poster is saying that the bi-products of the inflammation response in themselves can also cause a problem. Yes, the obesity is probably the "cause" in the first place, but telling a person to go on a weight loss diet is going to be a bit late if that's not going to save them before the inflammation kills them. If you've got 2 or 3 different things killing you at once, you're gonna have to deal…

While I don't disagree with the concept of prioritization, that's not the same as cause and effect. Inflammation is an effect that _can_ cause other problems. But as far as I know, inflammation is a symptom of other problems, not a cause in and of itself.

Did you read the article?

The article claims that inflammation is both a symptom of other problems (when in reasonable ranges of signalling) and a causer of problems (when signalling too much).

I know the title of the article itself is a bit sensationalist, but I would assume that any tests aiming to determine if inflammation is the cause of a problem in specific would also check to make sure that the inflammation was in the "starting to cause harm" range rather than merely in the "signalling" range.

Re: Inflammation might be the root of preventable disease

#188

Post by baccheion »

LinuxBender wrote: post #6

In my case, inflammation is a side effect of insulin resistance, like my fellow 83 million Americans with metabolic syndrome. If I can reverse the cause long enough, the liver should stop dumping fat into the adipose tissue and triglycerides may drop.

Vitamin D3 is said to help with metabolic syndrome. Also, intermittent fasting (eating within the same 8-hour window) and keto. Estrogen, DHEA, vitamin K2 MK-4, etc.

https://vitamindwiki.com/Overview+Metabolic+Syndrome+and+vit...

Re: Inflammation might be the root of preventable disease

#189

Post by baccheion »

hoseja wrote: post #109
rsync wrote: post #45

Inflammation ? Fasting. Just try it. It costs nothing.

Except major performance decrease. Some people cannot afford that.

When following an intermittent fasting protocol (eating within the same 8 hour window, for example), productivity tends to increase in the fasted state. Maybe there's some initial adjustment period.

Re: Inflammation might be the root of preventable disease

#190

Post by goda90 »

jepper wrote: post #4
whatshisface wrote: post #3

At the same time, anti-inflammatories slow wound healing. Here are a couple of random studies I found. https://www.ncbi.nlm.nih.gov/pubmed/17319622 https://www.ncbi.nlm.nih.gov/pubmed/22381097

same for NSAIDS (ibuprofen etc) and bone healing

They told my wife to only use Tylenol(acetaminophen, which isn't an NSAID)for pain when she broke her back. Inflammation has important uses, but like auto-immune disorders, too much can cause other problems.
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