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Inflammation might be the root of preventable disease

harvardmagazine.com

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Re: Inflammation might be the root of preventable disease

#61

Post by swader99 »

jniedrauer wrote: post #50
amluto wrote: post #24

Earlier quoted context omitted.

I can’t find the citation right now, but as I recall, a lot of connective tissue has very little blood flow. Inflammation increases blood flow, which can help with healing.

Achilles tendinosis is a good example of this. The achilles tendon replaces cells at a very slow rate. If there is chronic damage, it can take decades to heal on its own. But if you intentionally damage the area with eccentric heel drops, it can heal fairly quickly.

Doing a similar protocol with my patella tendon

Re: Inflammation might be the root of preventable disease

#62

Post by RobertRoberts »

refurb wrote: post #43
RobertRoberts wrote: post #7

How can a symptom be the "cause" of a disease? Gingivitis is "inflammation of the gums", but it's "caused" by bacteria, plaque, tarter, etc... inflammation is the description of what is happening (ie, symptom) not the "cause".

Inflammation is not just a symptom, but also an underlying process. Lots of things can cause inflammation, but the underlying process can be similar. And it can have good and bad effects.

Can you provide an example where inflammation _is_ the problem and isn't a symptom caused by something else (ie, disease, damage, toxicity, etc...)?

Re: Inflammation might be the root of preventable disease

#63

Post by rossdavidh »

My prediction: 1) reducing chronic inflammation by, for example, exercise or eating better food, is proven to have good health effects 2) pharmaceutical companies try to make that into a pill 3) dang, the benefits of the pill are not nearly as big as if you exercise and eat better food, and not nearly as big as our early trials of the drug indicated they would be 4) we must need a different kind of pill

Re: Inflammation might be the root of preventable disease

#64

Post by projektfu »

abledon wrote: post #59

What is inflammation really? Is it an excess of energy around that area? E.g. extra positive charges ?

I learned it as "rubor, tumor, calor, dolor, et functio laesa" meaning redness, swelling, heat, pain and loss of function. These are the classic signs and the reason it gets its name, as it's like a fire in the body. But as other commenters have said, it now seems to be the presence of certain signalling molecules or cell types that are associated with inflammation, and when people speak of it they may not be referring to any of the classical signs of inflammation. Which is a shame because now its lost the helpful etymology.

Re: Inflammation might be the root of preventable disease

#66

Post by ixtli »

rossdavidh wrote: post #63

My prediction: 1) reducing chronic inflammation by, for example, exercise or eating better food, is proven to have good health effects 2) pharmaceutical companies try to make that into a pill 3) dang, the benefits of the pill are not nearly as big as if you exercise and eat better food, and not nearly as big as our early trials of the drug indicated they would be 4) we must need a different kind of pill

Yup! I would also predict this. You simply can’t engineer your way out of needing better living conditions.

Re: Inflammation might be the root of preventable disease

#67

Post by abledon »

projektfu wrote: post #64
abledon wrote: post #59

What is inflammation really? Is it an excess of energy around that area? E.g. extra positive charges ?

I learned it as "rubor, tumor, calor, dolor, et functio laesa" meaning redness, swelling, heat, pain and loss of function. These are the classic signs and the reason it gets its name, as it's like a fire in the body. But as other commenters have said, it now seems to be the presence of certain signalling molecules or cell types that are associated with inflammation, and when people speak of it they may not be referri…

I'd like a physics level explanation.. when those molecules are there? whats going on at the atomic level, is there an excess of negatively or positively charged molecules ? When there is inflammation, there is usually heat, and heat means energy.

Re: Inflammation might be the root of preventable disease

#68

Post by cik2e »

et2o wrote: post #33
LinuxBender wrote: post #9

Earlier quoted context omitted.

I did. In fact that was a great start, but once you reach a certain point (in having metabolic syndrome), the Keto+IF reaches diminishing returns. It did bring me down 18 inches on the waist. The gut and hypertension will remain. In fact, my hypertension actually went up. To go further requires either Metformin or Berberine. I opted for Berberine, but time will tell.

Congratulations on your progress! Interested why you decided against metformin. Lots of people without DM or Metabolic syndrome are taking it for its apparent life extension effects (mostly unproven this far in humans). For diabetes, there's pretty solid evidence. I work in this space tangentially and I had not heard of berberine before. What are you hoping to achieve with this supplement?

Berberine has been shown to be as effective as metformin at controlling blood sugar with additional anti-depressive benefits.

https://examine.com/supplements/berberine/

Re: Inflammation might be the root of preventable disease

#69

Post by atomical »

m3nu wrote: post #57

More reason to keep an eye on hsCRP and take steps if it gets too high. (Most labs use The article brings together different issues, like fasting, fat tissue, exercise, diet, sugar and chronic disease. Reposted with a summary here: https://www.reddit.com/r/ketoscience/comments/bh2s9a/could_i...

This sounds like pseudoscience. Our lives are becoming dominated by fads and gurus just like our forebears.
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