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Ibuprofen alters human testicular physiology to produce compensated hypogonadism

ncbi.nlm.nih.gov

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Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism

#241

Post by ada1981 »

ada1981 wrote: post #239
ada1981 wrote: post #163

Earlier quoted context omitted.

You could also teach your kids meditation techniques to be deployed when in pain.

Unsure why this got downvoted, meditation has been show to reduce pain up to 90%. Seems like teaching kids to meditate would have all sorts of benefits, including drug free pain management. https://www.psychologytoday.com/us/blog/mindfulness-in-frant...

Can someone please explain the downvotes? Do you not like the idea that meditation can mitigate pain? Don’t think it’s true? Find it wrong to teach kids? What?

Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism

#242

Post by 14 »

stolsvik wrote: post #126
14 wrote: post #112

Earlier quoted context omitted.

My guess is the down vote comes from someone thinking your comment sounds like you don't have any children or know what you are talking about. You don't give ibuprofen for pain during a fever, though doctors will say it can help because often times the source of the fever will cause pain like an ear infection or strep throat, you give it to reduce the temperature. There is a serious risk of seizure in children if you…

Why do you not help your kids when they are in pain?! This is truly shocking to me, it is definitely a cruel and inhumane sentiment.

I meant in the sense I don't give pain killer for pain during a fever but I give it during a fever to help with the temperature. It is not to take away the pain of a fever but the temperature but often times there is something painful causing the fever so it helps. Now as for giving my kids analgesic I do give them Acetaminophen and Ibuprofen occasionally when they really need it. I encourage things like rest in a dark room and more fluids first but you get to know as a parent when they are really not well and when they just need to take a break from screen time or activity or take something like tylenol. Medicine is not my go to but I use it accordingly.

Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism

#243

Post by danjayh »

sgt101 wrote: post #217
coldtea wrote: post #177

Earlier quoted context omitted.

> how often do you measure the child's temperature As often as you need when they have a fever. Modern thermometers can give you the temperature in a minute or so.

yes, but is this sampling a good idea? Have you tried measuring temperatures periodically when the child appears well? What is the variation then? How do you know that the device is telling you something meaningful? Is the child getting flustered and hotter because of the attention?

You have to measure rectally for good results. Forhead thermometers, ear thermometers, under the tongue thermometers -- all crap. If you have an infant or small toddler, use a rectal thermometer. Measuring this way, results are both precise and accurate (and therefore, repeatable).

Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism

#245

Post by eaandkw »

whatshisface wrote: post #92
eaandkw wrote: post #22

Earlier quoted context omitted.

Clearly you have never been in the USMC. In hind sight it was pretty stupid but I have taken up to 1600mg per day for several days/ weeks in a row. We pretty much call the 800mg tablets grunt candy.

What is happening that gets everyone so inflamed? If you take a painkiller and go right back to the activity that damaged you you are begging for permanent injury.

Well, on the infantry side of the house thing like forced marches, ground fighting (MCMAP), field training, and live fire exercises all take a toll on the body. Most of the training requires brute force and most of the Marines because they are young don't take care of their bodies as much as they should. The other side of the equation is the fact that complaining about being hurt or injured tends to be looked down on. Everyone pretty much has a suck it up attitude.

In my 20 years I beat my body up pretty bad and I am paying for it now. I have had a couple of surgeries on my shoulders. I have bad knees, lower back, and some neck issues that I am trying to rehab and make better but I will never be 100%. I'm just shooting for less pain and more mobility.

Oh, and for going right back into the same activity after you injured yourself. That is just the job. The training keeps going. In a wartime situation you would not be able to quit if you get hurt. You just have to keep moving.

Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism

#246

Post by eaandkw »

gaius wrote: post #122
whatshisface wrote: post #92

Earlier quoted context omitted.

What is happening that gets everyone so inflamed? If you take a painkiller and go right back to the activity that damaged you you are begging for permanent injury.

Wear and tear on the knees generally. And yes, many infantrymen do have permanent problems by their 30's.

We usually have an expression that infantrymen age in dog years.

Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism

#247

Post by aejnsn »

aiyodev wrote: post #147
aejnsn wrote: post #35

Just had a kidney stone problem—first for me, quite painful experience. My ibuprofen dosage is 800mg every 8 hours, as needed. I had little choice. “Sustained” is the keyword of the study here. On another note, maybe this will drive alternative treatments such as CBD/marijuana for those who need to sustain their pain relief.

I’ve suffered from kidney stones off and on for years. Here’s what helps. Make sure you’re drinking enough water. 2 gallons per day minimum. If your pee isn’t clear, you’re not drinking enough. I add flavor packets to mine to make it more palatable. I carry a water bottle with me all day. Went from an attack once a month to once a year. Mix pain meds. It’s perfectly healthy. Don’t take 800 mg of ibuprofen. Take a nor…

Thank you so much! I’ve been trying to gather as many details as I can to make sure this happens less frequently. I have changed my entire diet, drastically cutting sugar consumption. I had an ER doctor tell me there’s no possibility of this being hereditary. However, kidney stones are a problem for my mother, one of her siblings, and both of my grandparents. Waiting on a urologist consultation, but it’s under control for now.

Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism

#248

Post by distant_hat »

logicchains wrote: post #62
sergiotapia wrote: post #43

Earlier quoted context omitted.

Same just did that. >resulted in the clinical condition named "compensated hypogonadism," a condition prevalent among elderly men and associated with reproductive and physical disorders. In the men, luteinizing hormone (LH) and ibuprofen plasma levels were positively correlated, and the testosterone/LH ratio decreased. Fuck that. I wonder what I should give my kids when they have fevers though

>I wonder what I should give my kids when they have fevers though You don't have to give them anything. Ibuprofen doesn't make the underlying infection causing the fever go away any quicker, it just alleviates the symptoms. It's a trade off between reducing short-term suffering and risking long-term defects. Personally my parents never gave me painkillers for fever and I'm grateful for it: fever pain is just a tempor…

Exactly this. It just works on the symptoms and children tolerate fevers fine as long as it is not too high (above 103F). But you have to endure a lot of crap from everyone breathing down your neck about how you are ignoring the child and are a cruel parent.

Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism

#249

Post by distant_hat »

babuskov wrote: post #107
logicchains wrote: post #62

Earlier quoted context omitted.

>I wonder what I should give my kids when they have fevers though You don't have to give them anything. Ibuprofen doesn't make the underlying infection causing the fever go away any quicker, it just alleviates the symptoms. It's a trade off between reducing short-term suffering and risking long-term defects. Personally my parents never gave me painkillers for fever and I'm grateful for it: fever pain is just a tempor…

I didn't downvote you, but you seem to lack experience/knowledge on the topic if you think it's only a painkiller. Ibuprofen's main use is to help to keep the body temperature in check. When your body temperature goes too high you can lose consciousness and even die. I had a very high fever once and didn't want to take any medicine until I started to lose consciousness and I almost fell while waiting in a line in pha…

True, but children are not that fragile. High (above 103/104) should be brought down, febrile seizures are bad but lots of parents hit ibuprofen/paracetamol when the kid is showing 99F.

Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism

#250

Post by distant_hat »

logicchains wrote: post #131
stolsvik wrote: post #126

Earlier quoted context omitted.

Why do you not help your kids when they are in pain?! This is truly shocking to me, it is definitely a cruel and inhumane sentiment.

Painkillers are not side effect free; if the pain is something minor, like a bruised knee or normal headache, it's not unreasonable to decide that experiencing the pain is a better choice than risking the side effects of a drug, which in uncommon cases can be much more severe and long term. It's not as clear cut as "helping" vs not helping, as unfortunately we don't yet have any side effect free painkillers.

Also, the pain sometimes keep activity low which may help with healing. If I give my kid something pain relieving he'll be up and bouncing around and could hurt himself more.
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