31–40 of 42 posts
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I was under the impression that past heavy (ab)users of opioids no longer get any analgesic benefit from them?
Yes, I had a friend who was an ex heroin addict, she needed huge quantities of any sort of painkillers to get any effect.
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For you or me that’s a really valid concern, but the damage to someone from opiate abuse is so extreme I think they’d take that risk. In fact some might even see the inability of a well meaning medical professional to dose them with an opiate as a feature, not a bug.
The hard part is that anesthesia is not just for comfort. I am not a doctor, but having the body in a low excitement mode for complex surgery must be an advantage. So resistance to anesthesia could mean no surgery beyond the most basic ones.
Opiates are painkillers, anesthetic are a different beast.
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> I don't think any of the people involved in the science here want to be doing paliative solutions, but rather it's the best they can get funding for. Elisabeth Rosenthal wrote An American Sickness about this phenomenon. This essay is a good preview: How Economic Incentives have Created our Dysfunctional US Medical Market - https://medium.com/@RosenthalHealth/how-economic-incentives-...
The claim in that article--"a lifetime of treatment is preferable to a cure"--is bonkers. It might be true if there was only one pharma company, but surely most companies would prefer that you buy their one-time cure than become a lifetime customer of their competitors. Diabetes is a particularly bad example because an ungodly amount of time and money has been spent trying to protect, repair, or regrow beta cells. De…
Before the middle of the 20th century, linseed oil and soybean oil were drying oils that were used to make stain and paint. When the paint producers figured out how to make paint from petroleum, the seed oil industry rebranded their product as "vegetable oil".
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Interesting points. Something else I'd point out is that science often goes through the trouble of finding paliative solutions rather than developing a fundamental understanding of the root causes. If you don't tackle the root causes of addiction, they'll respawn identically or in the form of other addictions, in my opinion. Re. your quote about the ego, I didn't quite get its meaning. Can you elaborate on it?
I don't think any of the people involved in the science here want to be doing paliative solutions, but rather it's the best they can get funding for. It's much harder to fund "we have to completely rework our public health infrastructure" (in the US, at least), then "We can help save these lives in ".
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The claim in that article--"a lifetime of treatment is preferable to a cure"--is bonkers. It might be true if there was only one pharma company, but surely most companies would prefer that you buy their one-time cure than become a lifetime customer of their competitors. Diabetes is a particularly bad example because an ungodly amount of time and money has been spent trying to protect, repair, or regrow beta cells. De…
Type-2 diabetes is a sham diagnosis. A key factor in the development of "insulin resistance" is the overconsumption of vegetable oils. These thin oils go rancid in the production process, and have to be "refined" to remove the rancid smell. Before the middle of the 20th century, linseed oil and soybean oil were drying oils that were used to make stain and paint. When the paint producers figured out how to make paint…
Why this isn't the focus, and instead people receive insulin, escapes my grasp.
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My thoughts exactly. So somebody gets this vaccine and then breaks their arm or goes into surgery, and suddenly there is no pain treatment available to them because of the vaccine.
I was under the impression that past heavy (ab)users of opioids no longer get any analgesic benefit from them?
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The hard part is that anesthesia is not just for comfort. I am not a doctor, but having the body in a low excitement mode for complex surgery must be an advantage. So resistance to anesthesia could mean no surgery beyond the most basic ones.
Opiates != Anesthesia Opiates are painkillers, anesthetic are a different beast.
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Opiates != Anesthesia Opiates are painkillers, anesthetic are a different beast.
Fentanyl is an extremely common ingredient in a surgical cocktail.
> Rather than activate the receptor, another drug called naltrexone blocks the receptor and can decrease cravings over time. Naltrexone is essentially a vaccine against both opioids and and alcohol. My recovered-alcoholic friend found that Naltrexone eliminated her ability to consume large amounts of alcohol. But she drank "to make it all go away", and Naltrexone didn't provide any relief for her emotional problems.…
As a quite heavy use alcoholic, I would gladly test any vaccine that worked on alcohol. Also, I've had a pretty amazing childhood with awesome parents. I still became addicted to cocaine a few times and I've done tons of drugs since my teens up to a couple years ago.