91–100 of 161 posts
I'm too afraid I would learn something awful about myself.
It's genealogy it's useful for. But genealogy, it's really useful for.
I'm too afraid I would learn something awful about myself.
Unfortunately you’d have no power to correct it. Even if such a thing were possible. I hope that changes.
Earlier quoted context omitted.
> But I do want to sequence it using a third-party Don't forget to change your DNA when the third party's database will eventually leak. (see the 21andMe's data leak: https://en.wikipedia.org/wiki/23andMe_data_leak )
They did not leak their database, the attacker guessed some user passwords and scraped those people's match lists. I don't think they even got their hacked user's test results - you can download those from 23andMe, as GDPR requires, but it's a "request your data" process which isn't so easy to do at scale without people noticing. 23andMe is also not NGS sequencing, so you get only a couple of 100000 letters randomly*…
I don't want to sequence at home. But I do want to sequence it using a third-party that gives me all the raw data. I live in Europe and I'm just a simple consumer. Does anyone know how I can do this? What service would I use / you can recommend? Them not keeping it on their side would be a huge bonus of course but not sure I can ask for that much.
> But I do want to sequence it using a third-party Don't forget to change your DNA when the third party's database will eventually leak. (see the 21andMe's data leak: https://en.wikipedia.org/wiki/23andMe_data_leak )
This feels like the acme of narcissism. How much time and money are people willing to spend on navel gazing?
On a reasonable level, navel gazing (the figurative kind) is maybe better called self-reflection. I use DNA for genealogy, and it seems to me from the people I meet, that many get a healthier approach to our identity once we learn more about our genetic background. Identity politics, collective identity building around ancestry - identity building of all kinds really - needs simple stories. And the stories DNA tell are never simple.
Earlier quoted context omitted.
They did not leak their database, the attacker guessed some user passwords and scraped those people's match lists. I don't think they even got their hacked user's test results - you can download those from 23andMe, as GDPR requires, but it's a "request your data" process which isn't so easy to do at scale without people noticing. 23andMe is also not NGS sequencing, so you get only a couple of 100000 letters randomly*…
I know you put an asterisk, but to make it clear: these locations are very far from random. They're the most informative positions, which is why we check them.
And the interesting positions are still reasonably randomly distributed by nature :)
It seems a bit odd to me to have a home lab for the sequencing and then feed it to a cloud LLM. I would have thought the point of the home lab is privacy.
With such cheap costs every city should be sequencing dog turds and sending out big fines. The pay back would be very quick.
Hmm, I'll come back in a few years when things have become cheaper.
Seems like maybe of the 3 dystopias: AI, Global Warming, Bio-warfare. That this is demonstrating that the home grown virus is closer than we think.