91–100 of 158 posts
Death is the ultimate equalizer. We take solace in the fact that no matter how rich, brutal, tyrannical, comically-villainous one is, death will surely come for us all. The day old-gizzards figure out how to sip on young-people juice and live forever, we are truly screwed.
Earlier quoted context omitted.
Pretty sure the possible world being lamented in the GP comment is not "everyone gets to live forever and stay healthy and youthful" but instead "there exist expensive, parasitic procedures which will allow some rich people to have drastically extended lifespans."
parasitic procedures You can be almost sure that once the underlying mechanism is known, the necessary stuff will be synthetised instead of being transferred from a young person to an older one. If only to guarantee stable supply, consistent quality and rule out accidental transmission of various pathogens from the donor.
Earlier quoted context omitted.
Pretty sure the possible world being lamented in the GP comment is not "everyone gets to live forever and stay healthy and youthful" but instead "there exist expensive, parasitic procedures which will allow some rich people to have drastically extended lifespans."
parasitic procedures You can be almost sure that once the underlying mechanism is known, the necessary stuff will be synthetised instead of being transferred from a young person to an older one. If only to guarantee stable supply, consistent quality and rule out accidental transmission of various pathogens from the donor.
Death is the ultimate equalizer. We take solace in the fact that no matter how rich, brutal, tyrannical, comically-villainous one is, death will surely come for us all. The day old-gizzards figure out how to sip on young-people juice and live forever, we are truly screwed.
Earlier quoted context omitted.
Modifying CSF turnover is not particularly novel, but I do think it is generally overlooked. CSF production cycling is greatly reduced in the elderly and and there are a lot of connections to memory diseases such as alzheimers. A few medical device startups have attacked the problem with promising results. Unfortunately, VC and national funding orgs aren't particularly interested in device based solutions because pil…
Can you share any more information about the medical device that showed efficacy against Alzheimers in the 200-patient trial?
There was also benefit across most measures, but just not of statistical significance.
The trial had some major problems with appropriate controls, and is widely cited as a poster child for why the FDA should not require a control group to undergo invasive brain-surgery, and how this can taint the results.
It also showed a 89% reduction in amyloid Beta, the same proxy measure Biogen's aducanumab was recently approved based on.
Death is the ultimate equalizer. We take solace in the fact that no matter how rich, brutal, tyrannical, comically-villainous one is, death will surely come for us all. The day old-gizzards figure out how to sip on young-people juice and live forever, we are truly screwed.
Death is the ultimate equalizer. We take solace in the fact that no matter how rich, brutal, tyrannical, comically-villainous one is, death will surely come for us all. The day old-gizzards figure out how to sip on young-people juice and live forever, we are truly screwed.
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Science has proved once again that we can cure MICE of just about anything. Maybe if we would let them experiment on us we get better human results.
Unless you're volunteering to let scientists poke at your brain, mice are the best option we have. https://www.yourgenome.org/facts/why-use-the-mouse-in-resear...