hi, i'm a just stupid waffle. can someone give me the TLDR of this [nearly] impossible to understand piece of writing?
From what I understand, is that if your body is quite good at fighting infection (and thus creates inflammation) you'll live longer. Seems a bit obvious to me, but what do I know? I'm not an academic scientist...
Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age
91–100 of 157 posts
Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age
#92Most people talk food when inflammation is mentioned. But let's not forget, arguably, an even bigger contributor: stress - mental or physical, say via a chronic illness. Relevant: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476783/#s2titl...
Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age
#93Earlier quoted context omitted.
https://en.wikipedia.org/wiki/Ramdev#Claimed_cure_for_COVID-...
If there's one thing that has become apparent during COVID, it's that there is great reason to be skeptical of "official government guidelines" of in situations like COVID (acutely emerging and constantly changing scenario.) They simply can't process information fast enough to make well informed statements. Now I don't have an opinion on ayurvedic medicine and it's legitimacy but something being "banned by the govern…
Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age
#94Earlier quoted context omitted.
From what I understand, is that if your body is quite good at fighting infection (and thus creates inflammation) you'll live longer. Seems a bit obvious to me, but what do I know? I'm not an academic scientist...
It's the other way around. Their finding is that lower levels of inflammation correlates with survival, capability and cognition in centenarians.
Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age
#95Most people talk food when inflammation is mentioned. But let's not forget, arguably, an even bigger contributor: stress - mental or physical, say via a chronic illness. Relevant: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476783/#s2titl...
Curious – are there legitimate ways to measure stress?
Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age
#96Earlier quoted context omitted.
yet everyone in the comments is sounding off as if this scientifically proves their random anecdotes about fasting
What’s wrong with fasting, isn’t it likely to increase life expectancy. I certainly feel better from this attempt at Ramadan (not religious just interested to try it as flat mate is Syrian). What evidence do you have that fasting -> less inflammation -> better ageing is wrong?
It’s wrong to frame the question as you did. The evidence should be provided to prove something, not disprove it. Is there enough evidence that fasting ultimately leads to better aging? If so, for which groups of people? Is there any underlying condition that negates the effect? That’s how science work, not the other way around.
Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age
#97Most people talk food when inflammation is mentioned. But let's not forget, arguably, an even bigger contributor: stress - mental or physical, say via a chronic illness. Relevant: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476783/#s2titl...
Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age
#98Most people talk food when inflammation is mentioned. But let's not forget, arguably, an even bigger contributor: stress - mental or physical, say via a chronic illness. Relevant: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476783/#s2titl...
CBD is great at helping alleviate inflammation in most people.
Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age
#99It's always strange to me how certain studies seem to gain so many upvotes on hackernews....a few thoughts: 1. This is a single study published in 2015, what does the wider literature say? Any dieticians or clinicians recommending anything from this? 2. The journal is EBioMedicine, which is not nothing but not exactly pre-eminent either. 3. This seems like just a common sense conclusion: "In Cox proportional hazard m…
I think you’re overthinking it. Certain studies gain so many upvotes on HN because they generate interesting discussion, and may be worth storing in our favorites for sharing and/or future reference. I almost always upvote articles when there is interesting discussion (or the potential for interesting discussion) related to the article. I very rarely (but do sometimes) upvote articles solely based on the content of t…
Re: Inflammation, but Not Telomere Length, Predicts Ageing at Extreme Old Age
#100Epigenetic clocks measuring methylation sites across DNA are currently the most accurate way to measure aging https://en.wikipedia.org/wiki/Epigenetic_clock What's more, it seems that it is possible to reset the epigenetic of cells to their youthful state and reverse actual the biological age of those cells. They don't just "measure younger", they function as they did when they were younger. https://www.nature.com/ar…