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Myocarditis Cases Reported After mRNA-Based Covid-19 Vaccination

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Re: Myocarditis Cases Reported After mRNA-Based Covid-19 Vaccination

#81
post #4

> To be clear: whoever gets heart inflammation from Moderna would’ve almost certainly got it worse from Covid. The issue arises from the spike protein itself. That’s why we don’t see myocarditis from non-MRNA vaccines like Astra Zeneca. https://twitter.com/joshzepps/status/1486213480823017472?s=2... Edit : Consider readied the entire Twitter thread. https://www.abc.net.au/radio/sydney/programs/afternoons/myoc... > It…

> That’s why we don’t see myocarditis from non-MRNA vaccines like Astra Zeneca. Does the AstraZeneca vaccine not include the spike protein? I thought it included the whole virus including the spike protein.

If it was just reaction to the spike protein then why is myocarditis more likely on the second vaccination?

I think it is therefore more likely that adaptive immune system is involved because it has ability to remember.

Now is it possible that spike protein itself or lipid shell is causing this based on incidence rate differences between 3 vaccines?

Hard to say.

The amount of spike protein produced is in correlation with amount of mRNA entering cells. The amount of mRNA entering cells is 3x higher with Moderna vaccine than with Pfizer vaccine and it appears that it is similar on both shots (first and second). But the amount of mRNA (converted from adenovirus DNA) entering cells with the second AZ shot is probably lower than on the first shot because there is also some immunity against the adenovirus and the dose size is the same.

This is in correlation with the amount of antibodies produced by these vaccines.

This is the not contradicting with the observation so far.

But it could be also lipid cell that has been found to cause inflammation. Considering the high amount of antibodies generated on the second vaccination, it is plausible that the lipid shells are not attacked by the immune system directly. But it might be possible that the cells are attacked after lipid shells have merged with their membranes.

There are few ways to find how what is most likely happening.

First is to hope that protein based vaccine from Novavax will be used by meaningful amount to detect proper incidence rates. When it is spike protein itself then we should see also high incidence rate on second vaccination.

The second option is to analyze mixed vaccinations where first vaccination was done with adenovirus vaccine and the second one with mRNA vaccine. It is not perfect setup but it might provide some additional information.

Third option is to use a mouse model similar to one in previous study where mouse were intravenously injected with mRNA vaccines. Repeat the study with mRNA vaccine, placebo (saline solution), dummy lipid shells and protein vaccines (might be necessary to do the study without and with the adjuvant).

Re: Myocarditis Cases Reported After mRNA-Based Covid-19 Vaccination

#82

Earlier quoted context omitted.

It's not one or the other any more, as You can easily catch symptomatic Covid being fully vaccinated, question is; does risk multiply, sum or maybe the vaccine somehow protects against it.

Sure there are breakthrough cases, but if you are unvaccinated the chances of catching covid are still much higher. And if you get myocarditis with the vaccine (which is rare) you will get it much worse with covid.

Actually, data from the only places which break this stuff out properly (like the UK) shows the rate amongst vaccinated people is massively higher than the rate amongst unvaccinated people. It's been like this for quite some time. Effectiveness is sharply negative by anywhere between 50% and 300% depending on age group.

Re: Myocarditis Cases Reported After mRNA-Based Covid-19 Vaccination

#83

Earlier quoted context omitted.

You aren't using anything. The scientists are, in a controlled way. That doesn't mean that it's a regular source. Yes, it's appropriate to use a no-validation report system to search for signal. Vaers is crap, but crap is actually what you want when you're saying "look how ridiculously wide I cast my net looking for examples."

Sure, I don't mind leaving it to the scientists. I'm just wondering "out loud" for 2 reasons: 1. "experts" have been relentlessly debunking vaers the past 2 years. This is even discussed in the limitations: "Given the high verification rate of reports of myocarditis to VAERS after mRNA-based COVID-19 vaccination, underreporting is more likely." 2. This isn't the first analysis of this kind, yet prior reports have emp…

> I'm just wondering "out loud" for 2 reasons:

because it feels like you're being a valuable skeptic, even though you aren't?

because you think "just asking questions," the way scare political news commentators, delivers something positive?

because you think the work of scientists should be judged based on the debunking of a source that has nothing to do with the science you're openly questioning?

because you've become so comfortable explaining your behavior to people who are openly telling you to your face that it's not appropriate that you don't even hear them saying "this isn't appropriate" anymore?

.

> prior reports have emphasized an important distinction

I took a look at your new link, and I don't see any important distinction being emphasized.

THIS IS NOT AN INVITATION FOR YOU TO EXPLAIN.

This is me saying "nothing is being emphasized to the point that someone who, unlike you, has domain specific training can even notice it."

In reality, you've hyper-focused on some irrelevant detail, and now you're desperately trying to figure out why that irrelevant detail isn't present other places.

"Well yes, don't you see? Sure, this paper is about fuel efficiency, but this one doesn't cover kerosene cars, and the other one emphasized an important distinction about kerosene cars"

In reality it's likely to be some detail the paper put in to silence a different walrus.

Yes, I see that you quoted a random statistical detail about age groups and likelihoods.

You want to know why this doesn't matter?

Every vaccine you've ever taken has this risk. All of them.

We just don't talk about it for the same reason that we don't talk about a seatbelt's risk of causing a broken rib, which can puncture your lung, and kill you. Happens twice a year in this country.

Why?

Because twice a year is nothing, and we don't want to spend the rest of our lives talking to people who really want to deeply study that twice a year number, as if there's something valuable there.

The real issue is you have no statistical intuition, so you don't recognize that you're wasting everyone's time chasing ghosts.

The downside, of course, is that STUPID PEOPLE CAN SEE YOU.

And they think you're challenging whether the vaccine is a good idea.

And no, it really doesn't matter if you say you aren't doing that. Stupid people see scary numbers and they remember what Fox News said, and they end up not taking the vaccine, because with five billion people worldwide having a dose in their arm, their dumb ass is so scared by people like you that they're still going to wait and see.

And you, desperate to feel intelligent, will not stop trying to ply these bullshit nonsense numbers, to show everyone else how much you get it.

Please stop doing this soon.

You're killing stupid people.

Re: Myocarditis Cases Reported After mRNA-Based Covid-19 Vaccination

#84

Earlier quoted context omitted.

https://www.cdc.gov/mmwr/volumes/71/wr/mm7104e1.htm?s_cid=mm... "rates among unvaccinated persons with a previous COVID-19 diagnosis were 29-fold lower (95% CI = 25.0–33.1) than rates among unvaccinated persons without a previous COVID-19 diagnosis in California and 14.7-fold lower (95% CI = 12.6–16.9) in New York. Rates among vaccinated persons who had had COVID-19 were 32.5-fold lower (95% CI = 27.5–37.6) than rate…

I'm using the term correctly and whether the numbers combine to indicate technical statistical difference won't impact that small difference, it would just reduce the error bars. Taking new york high end vaccine effectiveness 23.5x and worst case natural immunity 12.6x you reduce your hazard ratio by factor of 2. That is absolute worst case for natural immunity and best case for vaccine. It will be a lot closer to 1…

> I'm using the term correctly

> it would just reduce the error bars.

Significance is about the error bars. You are not using the term correctly.

The statement that you originally claimed to be incorrect remains true. It did not make any value judgments about whether a group is immune enough. It only made a factual claim that one group is less likely to get a symptomatic infection than another.

Re: Myocarditis Cases Reported After mRNA-Based Covid-19 Vaccination

#85

Earlier quoted context omitted.

Sure, I don't mind leaving it to the scientists. I'm just wondering "out loud" for 2 reasons: 1. "experts" have been relentlessly debunking vaers the past 2 years. This is even discussed in the limitations: "Given the high verification rate of reports of myocarditis to VAERS after mRNA-based COVID-19 vaccination, underreporting is more likely." 2. This isn't the first analysis of this kind, yet prior reports have emp…

> I'm just wondering "out loud" for 2 reasons: because it feels like you're being a valuable skeptic, even though you aren't? because you think "just asking questions," the way scare political news commentators, delivers something positive? because you think the work of scientists should be judged based on the debunking of a source that has nothing to do with the science you're openly questioning? because you've beco…

I'm sure that felt really good to get off your chest, but perhaps you'd like to offer a calmer follow-up with more factual arguments? Some of us readers appreciate them, and find them more thought-provoking than regular boring flame wars.

Re: Myocarditis Cases Reported After mRNA-Based Covid-19 Vaccination

#86

Earlier quoted context omitted.

Anecdotes become data at large n sizes. :) Also, if you’re theoretically vaccinated, wouldn’t that mean you don’t display symptoms if you contract the virus? Your family may have gotten omicron but the vaxx was effective and so you didn’t get sick enough to notice. That’s what the expert consensus, viz that the vaxx is effective, would predict, right?

Yes, the potential exists that some or all of us have had covid cases that were completely asymptomatic because we were vaccinated… which then just speaks to the miraculous effectiveness of these vaccines.

Agree. It’s hard to even remember any similarly successful pharmaceuticals. Maybe Lipitor or one of the recent hep c drugs, but I think Pfizer pulled in like 20 billion in the last year alone. Even more “miraculously effective” once you consider that it will be a few times a year drug rather than a “one and done.” Project Lightspeed was arguably the greatest achievement of our federal government since FDR.

Re: Myocarditis Cases Reported After mRNA-Based Covid-19 Vaccination

#87

Earlier quoted context omitted.

> I'm just wondering "out loud" for 2 reasons: because it feels like you're being a valuable skeptic, even though you aren't? because you think "just asking questions," the way scare political news commentators, delivers something positive? because you think the work of scientists should be judged based on the debunking of a source that has nothing to do with the science you're openly questioning? because you've beco…

I'm sure that felt really good to get off your chest, but perhaps you'd like to offer a calmer follow-up with more factual arguments? Some of us readers appreciate them, and find them more thought-provoking than regular boring flame wars.

No post body was provided.

Re: Myocarditis Cases Reported After mRNA-Based Covid-19 Vaccination

#88

It's important to mention that catching COVID also causes myocarditis https://www.cdc.gov/mmwr/volumes/70/wr/mm7035e5.htm Edit: this article says out of 192 405 448 people, 1626 had myocarditis, or about 0.0008%. In contrast, the CDC estimates COVID has a 0.146% chance to give you myocarditis.

I am fully vaccinated and, as I'm typing this, recovering from COVID.

Do tell me more about this vaccine/disease exclusivity. I must be doing something wrong.

Re: Myocarditis Cases Reported After mRNA-Based Covid-19 Vaccination

#89

Earlier quoted context omitted.

I'm sure that felt really good to get off your chest, but perhaps you'd like to offer a calmer follow-up with more factual arguments? Some of us readers appreciate them, and find them more thought-provoking than regular boring flame wars.

Quoted post unavailable.

Were you not so engulfed in righteous outrage, you might have noticed you're replying to a different person.

Maybe you should take their advice after all, and exercise some tranquility.

Re: Myocarditis Cases Reported After mRNA-Based Covid-19 Vaccination

#90

Earlier quoted context omitted.

Quoted post unavailable.

Were you not so engulfed in righteous outrage, you might have noticed you're replying to a different person. Maybe you should take their advice after all, and exercise some tranquility.

No post body was provided.
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