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Ibuprofen alters human testicular physiology

pnas.org

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Re: Ibuprofen alters human testicular physiology

#81

Post by badosu »

disconnected wrote: post #47
jgust wrote: post #33

Earlier quoted context omitted.

See: The NFL

When I think "painful initiation ritual", I think "glove made out of bullet ants" [1] not "organized sporting event in which everyone is wearing armor and hurting someone badly is grounds for stopping the game and rushing him/her to the hospital". Even if you pick something like Boxing or similar contact sports where the goal is to intentionally hurt your opponent, it is still a far-cry from sticking your hand into a…

Ironically maybe having a glove full of ants once in a while is safer than shocking your head repeatedly every week for years...

Re: Ibuprofen alters human testicular physiology

#82

Post by marpstar »

ardit33 wrote: post #23

If you hang around bodybuilding forums you will hear to avoid Ibuprofens as they hurt your ‘gains’ Perhaps bro-science was right in this case

Your comment intrigued me so I Googled and found this[1] article. Not sure what to think. The sample size in the study was even smaller than that in the original article.

[1]: https://www.ncbi.nlm.nih.gov/pubmed/18461099

Re: Ibuprofen alters human testicular physiology

#83

Post by jamez1 »

antisthenes wrote: post #70
joezydeco wrote: post #37

Earlier quoted context omitted.

Can't use aspirin in children and teenagers because of the risk of Reye's Syndrome. https://www.mayoclinic.org/diseases-conditions/reyes-syndrom...

1000 cases in the US, which means you're about 30x more likely to die in a car accident in any given year. Also, the syndrome isn't immediately lethal. When people worry about infinitesimally small risks, it always makes me chuckle.

That's 1000 cases when we restrict children from taking aspirin, it could be a lot more once we let them

Re: Ibuprofen alters human testicular physiology

#84

Post by badosu »

cookiecaper wrote: post #61
MollyR wrote: post #3

It would be mind boggling if pain killers were connected to dropping male fertility. It might even explain why so many cultures had rites to male adulthood involving extreme pain.

Where can I read about "dropping male fertility" as a medical thing? Just taking a blind guess, as someone who doesn't follow the medical field, I would suggest that increases in "infertility" are much more likely to be caused by the older age at which people are becoming interested in "fertilization" than environmental factors causing biological malfunctions. In other words, it's not that reproductive systems are br…

There are some metrics that are related to fertility like ejaculation volume and sperm motility[0].

0: https://en.wikipedia.org/wiki/Sperm_motility

Re: Ibuprofen alters human testicular physiology

#85

Post by rhexs »

ChristianGeek wrote: post #55
TheSpiceIsLife wrote: post #38

Earlier quoted context omitted.

In case you were wondering: Cannabidiol (INN;[3] abbreviated as: CBD) is one of at least 113 active cannabinoids identified in cannabis.[4][5] It is a major phytocannabinoid, accounting for up to 40% of the plant's extract. https://en.wikipedia.org/wiki/Cannabidiol

It’s worth noting that a legal version, extracted from Hemp (a form of Cannabis that has no psychoactive properties), is available via mail order anywhere in the U.S.

I looked into the hemp based extract a while back and the conclusion I drew was that it was up for debate whether or not it was legal. Proponents cited a bunch of laws regarding industrial hemp while the DEA seemed to have another position entirely. Was this finally settled or is it still a bit gray?

Re: Ibuprofen alters human testicular physiology

#86

Post by lloeki »

rdruxn wrote: post #24
kinkrtyavimoodh wrote: post #18

Earlier quoted context omitted.

I sometimes imagine, with horror, what would happen if after 500 years of progress, humanity were to realize that almost all cultural practices they painfully, one by one, undid, were all sensible to begin with for reasons that humanity didn't previously understand.

What an interesting writing prompt

Indeed, and submitted[0] right away.

[0]: https://www.reddit.com/r/WritingPrompts/comments/7p2ubq/wp_a...

Re: Ibuprofen alters human testicular physiology

#87

Post by kinkrtyavimoodh »

Pxtl wrote: post #12

Is it callous of me not to worry about the testosterone levels of professional athletes? Because they seem to generally have enough. I worry more about people with RSI who often depend on overuse of anti-inflammatory meds and aren't demonstrably professionally masculine.

No one is asking you to worry about professional athletes in specific. If the effect is demonstrated to be applicable to men in general, it would also affect the people you mentioned.

Re: Ibuprofen alters human testicular physiology

#88

Post by taneq »

Grazester wrote: post #19
fencepost wrote: post #13

Okay, so ibuprofen impacts testicular function, acetaminophen/paracetamol causes muting of emotional response (along with the liver toxicity), many other painkillers are related to ibuprofen, and opiates are Right Out. Is aspirin at least reasonably safe as long as the blood thinning isn't a problem?

I tend to use naproxen but something tells me that would kill me as well

Funny thing, naproxen is much kinder to your stomach than ibuprofen, but it's not generally used (and may be prescription-only?), in Australia at least. It does, however, carry a minutely increased risk of heart attack / stroke. I guess they'd rather give 1000 people ulcers than 1 more person die in a lawsuit-attracting fashion.

Re: Ibuprofen alters human testicular physiology

#89

Post by crx087 »

dwyerm wrote: post #28
Grazester wrote: post #19

Earlier quoted context omitted.

I tend to use naproxen but something tells me that would kill me as well

I think that all NSAIDs (like naproxen and ibuprofen) chew holes through your stomach lining, and a whole class of them were yanked from the market for causing heart attacks[1]. (But, yeah, naproxen seems to be one of the safest ones...) [1] https://en.wikipedia.org/wiki/COX-2_inhibitor

> (But, yeah, naproxen seems to be one of the safest ones...)

Kind of.

But it starts to feel a little uneasy taking it all the time once you realize that naproxen's regulatory approval came from https://en.wikipedia.org/wiki/Industrial_Bio-Test_Laboratori... data.

Re: Ibuprofen alters human testicular physiology

#90

Post by acchow »

kinkrtyavimoodh wrote: post #18
MollyR wrote: post #3

It would be mind boggling if pain killers were connected to dropping male fertility. It might even explain why so many cultures had rites to male adulthood involving extreme pain.

I sometimes imagine, with horror, what would happen if after 500 years of progress, humanity were to realize that almost all cultural practices they painfully, one by one, undid, were all sensible to begin with for reasons that humanity didn't previously understand.

“If the stars should appear one night in a thousand years, how would men believe and adore; and preserve for many generations the remembrance of the city of God”
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