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Ibuprofen alters human testicular physiology

pnas.org

31–40 of 216 posts

Re: Ibuprofen alters human testicular physiology

#32

At 1200mg/d, I feel like destroying your reproductive system would be the least of your concerns.

That is actually the dose I use for my lower back pain and inflammation when it flares up - for a couple of days perhaps once or twice a year. Dates from a slipped disc about 20 years ago. Never serious enough for surgery, but still unpleasant.

Re: Ibuprofen alters human testicular physiology

#33
post #3

It would be mind boggling if pain killers were connected to dropping male fertility. It might even explain why so many cultures had rites to male adulthood involving extreme pain.

> It might even explain why so many cultures had rites to male adulthood involving extreme pain. Right. And a notable trend among those cultures is that they are all nearly extinct. So much for their fertility. Of course this observation could biased due to my own ignorance. I only remember, like, 3 such cultures, and they were your typical African/Amazonian/Aboriginal tribes that still live in near-neolithic conditi…

See: The NFL

Re: Ibuprofen alters human testicular physiology

#34
post #3

It would be mind boggling if pain killers were connected to dropping male fertility. It might even explain why so many cultures had rites to male adulthood involving extreme pain.

> It might even explain why so many cultures had rites to male adulthood involving extreme pain. Right. And a notable trend among those cultures is that they are all nearly extinct. So much for their fertility. Of course this observation could biased due to my own ignorance. I only remember, like, 3 such cultures, and they were your typical African/Amazonian/Aboriginal tribes that still live in near-neolithic conditi…

Fertility is only one aspect of evolutionary fitness.

Re: Ibuprofen alters human testicular physiology

#35

Okay, so ibuprofen impacts testicular function, acetaminophen/paracetamol causes muting of emotional response (along with the liver toxicity), many other painkillers are related to ibuprofen, and opiates are Right Out. Is aspirin at least reasonably safe as long as the blood thinning isn't a problem?

Infrequent, occasional use of opiates, for two or three days shouldn't be a problem. You do have to make a bit of an effort to get addicted to opiates, insofar as taking a pill a day for a couple of weeks constitutes effort.

Re: Ibuprofen alters human testicular physiology

#37

Okay, so ibuprofen impacts testicular function, acetaminophen/paracetamol causes muting of emotional response (along with the liver toxicity), many other painkillers are related to ibuprofen, and opiates are Right Out. Is aspirin at least reasonably safe as long as the blood thinning isn't a problem?

Can't use aspirin in children and teenagers because of the risk of Reye's Syndrome.

https://www.mayoclinic.org/diseases-conditions/reyes-syndrom...

Re: Ibuprofen alters human testicular physiology

#38

Okay, so ibuprofen impacts testicular function, acetaminophen/paracetamol causes muting of emotional response (along with the liver toxicity), many other painkillers are related to ibuprofen, and opiates are Right Out. Is aspirin at least reasonably safe as long as the blood thinning isn't a problem?

Well you can still use CBD though.

In case you were wondering: Cannabidiol (INN;[3] abbreviated as: CBD) is one of at least 113 active cannabinoids identified in cannabis.[4][5] It is a major phytocannabinoid, accounting for up to 40% of the plant's extract.

https://en.wikipedia.org/wiki/Cannabidiol

Re: Ibuprofen alters human testicular physiology

#39
post #3

It would be mind boggling if pain killers were connected to dropping male fertility. It might even explain why so many cultures had rites to male adulthood involving extreme pain.

I sometimes imagine, with horror, what would happen if after 500 years of progress, humanity were to realize that almost all cultural practices they painfully, one by one, undid, were all sensible to begin with for reasons that humanity didn't previously understand.

> I sometimes imagine, with horror, what would happen if after 500 years of progress, humanity were to realize that almost all cultural practices they painfully, one by one, undid, were all sensible to begin with for reasons that humanity didn't previously understand.

Especially since modern cultural change seems to have a tendency to be driven by the youngest politically-aware cohorts. Not a lot of time to acquire wisdom that might prevent that, if you're so young you haven't even collected enough knowledge yet.

Re: Ibuprofen alters human testicular physiology

#40

Okay, so ibuprofen impacts testicular function, acetaminophen/paracetamol causes muting of emotional response (along with the liver toxicity), many other painkillers are related to ibuprofen, and opiates are Right Out. Is aspirin at least reasonably safe as long as the blood thinning isn't a problem?

* and stomach ulcers
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