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What Ozempic does to the gut-brain axis

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Re: What Ozempic does to the gut-brain axis

#521
post #23

Earlier quoted context omitted.

I got pancreatitis from Zepbound, but it was indirect. Turns out rapid weight loss can cause gallstones, especially if you're genetically predisposed to them. I had one that ended up stuck in the bile duct, causing acute pancreatitis. I had to get my gallbladder removed shortly after and hundreds of stones were found. I would consider getting an ultrasound since the stones don't just go away when you stop taking the…

Wouldn't that be cholecystitis (and a cholecystectomy), not pancreatitis?

As the other commenter said, the gallbladder and the pancreas both share a duct, and if the stone is low enough you get pancreatitis from a gallstone. I was just that lucky.

Re: What Ozempic does to the gut-brain axis

#522

Earlier quoted context omitted.

>But this intelectual knowledge doesn't really help if your body is telling you it's hungry all the time and it's hard not to eat something. Better choices can help, because different calories deliver different satiety; but some people don't get much satiety no matter what they eat. Maybe try to figure out why you’re feeling hungry. Is it because you’re running a 1000 kcal deficit? Can your body really tell whether y…

> Maybe try to figure out why you’re feeling hungry. Is it because you’re running a 1000 kcal deficit? For me I always feel hungry. Always ready to eat more. Always. It doesn't seem to matter what I eat or how much, I have no "off switch" apart from maybe being asleep. I sit at big family meals like Christmas or thanks giving and people around me are all "man I am going to pop if I have another bite" and yet I am sti…

This is exactly me. I'm grateful that real medical solutions exist.

Re: What Ozempic does to the gut-brain axis

#523

Earlier quoted context omitted.

What evidence do you have that it is a cultural shift, rather than, say, a chemical in the environment that wasn't there before, or a difference in the food supply?

Are food options today not more calorie-dense than they were back in time? More easily accessible? Calories have become increasingly cheap and dense to come by. You've lots of processed food being engineered to be highly palatable and calorie dense at an industrial scale. Plus, cars and all "comforts" eating into your physical activities?

All of those may be correlated to the rise in obesity. I see no evidence that any of them is causal. I don't even think all of them are correlated, honestly. The rise in the number of calories available certainly is, but cars and suburbs have been around longer than that. And the rise in calories may just be a response to increased demand.

Re: What Ozempic does to the gut-brain axis

#524
post #177

Earlier quoted context omitted.

The issue isn't food addiction, it's a broken hunger response (broken by Howard Moskowitz intentionally in the name of profits)... You have to change your food regimen completely (higher fiber, more protein, less sugar, less carbs, less fat), and that's tough to do when you're surrounded by options that aren't... I think the real problem is that the symptom we're trying to treat is "overweight", and it's actually a t…

What breaks the hunger response, and how does one fix it? Maybe it's well-known, but I read the starvation response Wikipedia page[0] and didn't grok it. [0] https://en.wikipedia.org/wiki/Starvation_response

For me, the simple shift of moving to eating 0.7g of protein per pound of body weight every day did it... It was not enough on it's own (I also eat more fiber, less fat, less carbs, though less does not mean none), but that alone was a night and day difference, and enough to change the story.

Re: What Ozempic does to the gut-brain axis

#525

Earlier quoted context omitted.

How much and how long do you want the bet you go for? How do you even want to define "harms". Let's say there's a road from the gut to the brain. If today's ultra processed food is motorcycles ripping down the road as fast as possible, and Ozempic is the police, saying whoa there, slow down, buddy, then from the POV of the motorcyclists that's harmful, but for everyone else around them, that's good.

https://en.wikipedia.org/wiki/Straw_man

https://en.wikipedia.org/wiki/List_of_fallacies

I can link to Wikipedia too. Which part is the straw man?

Re: What Ozempic does to the gut-brain axis

#526
post #433
post #356

Earlier quoted context omitted.

Your first sent once and your last sentence don't align. Yes. Fruits are healthy. One orange is healthy. 10 oranges are unhealthy. Same concept applies to water. Drinking too much can be unhealthy as well, but that doesn't change the fact that water is good.

> 10 oranges are unhealthy You made that up tho.

I know Math is hard for you, so let me explain it:

10 oranges have a total of roughly 700 calories and 120 grams of sugar while only having 30 grams of fiber. It's mainly sugar. Eating 10 oranges per day crowds out protein, fat and other nutrients.

It's not a made up claim. You are a made up claim, troll.

Re: What Ozempic does to the gut-brain axis

#527

Earlier quoted context omitted.

But that's not what the pharma companies want. They want you on the lifetime prescriptions that don't actually address the underlying problem.

Are they hiding true solutions treating the underlying issues?

A researcher who discovered a "true solution" would be fired or assassinated or discredited via propaganda to utter irrelevance. Too many incoming billions at risk.

Re: What Ozempic does to the gut-brain axis

#528

Earlier quoted context omitted.

It does which is why medically supervised weight loss with GLP1s includes diet recommendations to mitigate this. But in my experience, decreased cravings make it easier to choose food rationally. The food noise that causes people to overeat usually doesn’t cause them to overeat healthy foods anyway.

> But in my experience, decreased cravings make it easier to choose food rationally. The food noise that causes people to overeat usually doesn’t cause them to overeat healthy foods anyway. "Food noise" is much more than just craving calories, we have cravings for most of the different nutrients we need. That is how people ate a balanced diet in history even though it was much harder to do back then, peasants craved…

Anecdotal, but I think we need to consider that modern marketing and supply chains have a huge impact here. Without any cravings control, my mind was perfectly happy craving burgers, fries, and pizza 24/7 for thirty years. It hated every bite of veggies.

Re: What Ozempic does to the gut-brain axis

#529
post #265

Earlier quoted context omitted.

People can get fat by eating too much healthy food.

That's the problem with the definition of "healthy". No single food is "healthy" on it's own. It's a wrong way to look at it and why most people fail at finding a good diet. There's no super food you can just eat unlimited amounts of. A diet can be healthy if it's the nutrient combination of different foods that result in certain number of calories, protein, fat, carbs, minerals and vitamins per unit of time.

You also have to adjust those numbers over time based on input and output. Your body’s energy system isn’t closed.

Re: What Ozempic does to the gut-brain axis

#530
post #401

Earlier quoted context omitted.

Wasn't there just a study, that many fat kids are fat because of fruit juices? Healthy in a way, but surprisingly a lot of sugar ( either added or from the fruits)

There was a study comparing big and small eaters with and without obesitas. Turns out that skinny people who eat a lot eat also eat a lot of fat and protein and that fat people who eat almost nothing eat mostly carbs and sugar.

Link to the study would help that claim, when you have a chance.
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