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Antibiotics nearly double risk of developing IBD, doctors warn

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Re: Antibiotics nearly double risk of developing IBD, doctors warn

#51

Post by dialamac »

blix wrote: post #48
dialamac wrote: post #33

Earlier quoted context omitted.

While I empathize with ibs sufferers, this is nonsense. Nobody with ibs poops large quantities of blood, needs their colon removed in many cases, or surgery because their bladder and bowel are now suddenly connected. We don’t fully understand most disease processes, even those for which we have some effective treatments. I don’t think lumping disparates diseases together simply on the axis of “understanding of diseas…

I think there are many more similarities between IBS/IBD than the current understanding of disease process. People IBS/IBD (especially mild IBD) have more in common with each other than folks with other chronic illnesses. For instance, your sibling comments story about seeking treatment for IBS is very similar to many IBD stories as well. IBD is itself a lumping of disparate diseases based on very minimal understandi…

My point is there is you’re providing very little of substance to show that IBS and IBD are related diseases. Just because we know little about either doesn’t mean much. IBS is unfortunately by its nature typically a diagnosis of exclusion while IBD of all forms is diagnosed strongly by both clinical history and laboratory/histopathological data.

Re: Antibiotics nearly double risk of developing IBD, doctors warn

#52

Post by steve_adams_86 »

maybookers wrote: post #37
steve_adams_86 wrote: post #21

I once had to take antibiotics like crazy for a long time because I had some pain in the ass strep that wouldn’t go away. It was quite the experience. Afterwards, my breath was bizarre smelling, I had these horrible sulphuric burps for months, and I couldn’t digest ANYTHING properly. It was misery. I had such painful gas from indigestion so frequently that eating totally lost its appeal. This stacks up right in my ex…

Sounds familiar to me. Had two big antibiotic treatments after dental surgeries last year. This did not feel right. How did you get rid of the problems? Change in diet?

This is insanely anecdotal and doesn't hold any scientific integrity, but:

I ate a lot of raw, sometimes fermented, vegetables and fruit. Generally high in fibre. I avoided foods I'd need to wash much because I was trying to fill my system with a diversity of bacteria. A bit of dirt was part of the goal. I ate stuff out of my garden, from a little local organic farm, foraged foods like berries and mushrooms, etc.

No idea if that's what helped, but I'm totally fine now. Whatever I did before wasn't working, or wasn't working quickly. Once I went to my mostly plant-based "dirty" diet, so to speak, the improvement was rapid. But it didn't happen in isolation, either. I also reduced my intake of animal proteins mostly, which would probably be a significant factor in digestion. Eggs would reduce the presence of sulphuric gases especially.

I'm not a believer in pro-biotics (they don't seem to support diversity, which seems essential), but I believe people should eat a lot of diverse bacteria in their foods. Things like wild mushrooms, plants grown in your yard that aren't extensively washed and peeled. Don't cook everything to death. Let some little critters into your system and let them do their thing. Assuming you don't get the particularly bad ones (usually easy to avoid if you know how the food is grown), I can't think of easier ways to introduce the diversity required to properly populate your GI tract.

Again though, I have no idea what I'm talking about. I'm just some guy who eats dirty carrots in his yard.

Re: Antibiotics nearly double risk of developing IBD, doctors warn

#53

Post by deorder »

trhway wrote: post #50
deorder wrote: post #45

Earlier quoted context omitted.

3 years ago I got diagnosed with IBS after I landed in the hospital with a stabbing pain just right next to my belly button (sometimes I still feel it lightly) what they first thought was caused by kidney stones. Nothing turned up on the xrays or echoes. Since then things have only gotten worse as if it has spread upwards first causing constipation, then silent reflux (causing a constant burning sensation in my throa…

[IANAD] what you describe might as well be SIBO (as far as i understand in my limited non-professional understanding the bacterial overgrowth can cause the IBS symptoms too though fortunately i was spared that). It took some years in my case to stumble upon definitive test - the lactose based breath test - with all these years doctors dismissing it as "just take the antacid" (which is actually no-no for SIBO), and ev…

Yes, they gave me different antacids and so far nothing has helped. I wish it was just like a regular acid reflux, but best way to describe it is as if there is a cloud of aerosolized acid being released from my esophagus 24/7 that is spreading and causing an non-stop burning sensation everywhere it gets inside my throat, mouth, nose, eyes and I think it is damaging my larynx. None of the usual advice seems to help. Days that I am feeling better I can eat an entire chocolatebar, mint tea, lay / sleep flat, everything I should not do and it does not get worse. Something I noticed though is that it disappears everytime I go on vacation and actually eat worse than usual (McDonald's etc.)

Never had any test done for SIBO I think. They did a stool test, sigmoidoscopy and found nothing. That is how I ended up being diagnosed with IBS.

Re: Antibiotics nearly double risk of developing IBD, doctors warn

#54

Post by projektfu »

selimthegrim wrote: post #34
projektfu wrote: post #14

Earlier quoted context omitted.

Most antibiotics prescribed for UTI are bacteriocidal. Penicillins like amoxicillin and fluoroquinolones are probably the most popular.

Fluoroquinolones due to sequelae on connective tissue and retinas are not first line treatments for UTI anymore https://blogs.bcm.edu/2018/07/25/antibiotic-ciprofloxacin-in... https://www.acsh.org/news/2012/04/05/keep-eyes-open-using-ci... https://sites.google.com/site/levaquininfo/

https://www.contagionlive.com/news/cdc-analysis-suggests-flu...

Re: Antibiotics nearly double risk of developing IBD, doctors warn

#55

Post by ineedasername »

mleonhard wrote: post #40
ineedasername wrote: post #20

Honestly I thought that was pretty well known already. I knew a girl in college about 20 years ago who had been on massive amounts of anti-biotics, and it ruined her stomach & digestive system in some way. At the time she was having to slowly build up "good" bacterial through some type of specialty yogurts (might just have been probiotics, which were not as prevalent then). It was a multi-year process though, and she…

Why didn't she just get a fecal transplant?

This was 20 years ago. While not brand new at the time, it wasn't very common.

A lot of work on FMT has only taken place in the last decade. I don't think there was even a randomized trial for it as a treatment method until the last 10 years.

Re: Antibiotics nearly double risk of developing IBD, doctors warn

#56

Post by azinman2 »

slim wrote: post #38
azinman2 wrote: post #2

Makes a lot of sense. We know so little about the trillions of bacteria inside of us, and taking a nuke to them all is going to have consequences. There are probiotics tuned for IBD on the market, and one can only imagine the complexities of the ecological dynamics. I personally believe that in 100 years there will be a real bacterial awakening in science understanding how much our microbiome affects so much about ou…

Important gut bacteria may have gone extinct and we did not even notice

Then it couldn’t have been that important.

Re: Antibiotics nearly double risk of developing IBD, doctors warn

#57

Post by sparkie »

PaulBGD_ wrote: post #32
sparkie wrote: post #7

Purely an anecdote: I wrote in a related thread about 5 years ago how I had an allergic reaction and my guts became a mess after taking antibiotics for the first time in my life (around age 23) [ https://news.ycombinator.com/item?id=10555891 ]. I managed to get better by changing my diet. In 2017 I had another course of antibiotics, got very ill again and was hospitalized, diagnosed with IBD (UC), and spent nearly 13…

This is a shot in the dark, but I had taken antibiotics to treat an infection twice last fall, then suddenly this summer have been having unexplainable (so far) stomach issues. Given the somewhat longer period after taking the antibiotics, is the length of time somewhat similar to yours?

Yeah, it could be similar. (Can't remember clearly first time as it was 10 years ago now).

Second time my stomach complaint got really bad, my doc assumed it was gastroenteritis and prescribed me more antibiotics. They were useless, and he figured it might be IBD a few weeks later and prescribed me some steroids (Prednisolone). The dose of steroids prescribed was useless as I already had severe symptoms by then, so I ended up hospitalized and pumped with a high dose of Hydrocortisone. If it were a few days later I probably would've been dead.

For a few months before my guts were bad, I was having pains in my chest (around the bottom of the ribcage). The doctor thought it was gallstones, but a UV scan came back negative. The pains in the lower part of the colon came afterwards, along with the diarrhoea.

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