The next thing to test: Does a fecal transplant after taking antibiotics eliminate the increased risk of developing IBD?
Antibiotics nearly double risk of developing IBD, doctors warn
41–50 of 57 posts
Re: Antibiotics nearly double risk of developing IBD, doctors warn
#42Antibiotics cured my IBD. Had problems for years. A brief course of amoxicillin and some other, now forgotten, antibiotic (taken for unrelated reasons,) ended it almost immediately. It was amazing. What wasn't so good was catching C. diff. soon after, almost certainly because of the aforementioned antibiotics. Another treatment of yet another antibiotic dealt with that. Net result; no IBD.
Related: Antibiotics cured, for about a year, my severe gluten and corn intolerance. Then the gluten intolerance ame back. Ive gone through a few rounds of eliminating the gluten issues in this fashion, but the symptoms always return 10-16 months later.
Can you describe what you mean by your intolerances here?
I'm having a similar issue that developed after taking antibiotics and I'm curious if yours is similar.
Re: Antibiotics nearly double risk of developing IBD, doctors warn
#43Honestly I thought that was pretty well known already. I knew a girl in college about 20 years ago who had been on massive amounts of anti-biotics, and it ruined her stomach & digestive system in some way. At the time she was having to slowly build up "good" bacterial through some type of specialty yogurts (might just have been probiotics, which were not as prevalent then). It was a multi-year process though, and she…
Why didn't she just get a fecal transplant?
Because you can't. They're reserved for c-diff infections and there isn't much risk data on use cases outside of that such that regular providers won't give it the OK.
Re: Antibiotics nearly double risk of developing IBD, doctors warn
#44Let me explain my case here. 2 months back I was having stomach pain around the abdomen, it comes and goes, especially its a bit high after taking food. Consulted doctor, and he gave medicines assuming its gastritis, without antibiotics. Lipid profile was normal, SGPT was a bit higher (55 U/L)A Urea Breath test showed that I am positive for H-Pylori.
A USG abdomen showed a gaseous proximal colon along with mild wall thickening of sigmoid and adjacent descending segment around left lilac fossa (Radiologist assumed either spastic colon/ sequela of colitis). The Doc started treatment with antibiotics Amoxidin(Amoxicillin) + Flagyl(Metronidazole) for 14 days along with Gordex and Gaviscon for gastritis. After 14 days, the pain has drastically reduced, but I started having constipation, minor fissure. Consulted doc again, and he gave Flagyl(Metronidazole) for 7 days along with lactulose. Stomach pain actually went away when I started taking lactulose also H-Pylori was not detected on the next test(using H-Pylori antigen stool test).
When I stopped the medicines again, the constipation and occasional stomach pain came back. I started taking lactulose 2 times a day after the 14 + 7 days antibiotic course, everything was smooth, but when I stopped lactulose, stomach pain came back. I have then started reading about the symptoms and somewhere I read about gut flora and how antibiotics damages gut flora, on reading much I started asking my doc about probiotics.
He recommended a probiotic which said Colon support containing 20 billion CFU. The mix of probiotics was Bifidobacteria blend(18 billion CFU) (Bifidobacteria lactis, Bifidobacteria infantis, Bifidobacteria longum, Bifidobacteria breve, Bifidobacteria bifidum)) along with Lactobacillus Blend(1.5 Billion CFU) (Lactobacillus rhamnosus, Lactobacillus plantarum, Lactobacillus casei, Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus helverticus) and Stephalococus Thermophilus (500 million CFU). Taking a probiotic capsule for 6 days has improved a lot, and I have a smooth stomach motion, and doesn't have the stomach pain or constipation anymore.
What I knew from Doc is, if we eat prebiotic (Food with good fiber), it is decomposed by good bacteria and they reproduce good. On the other hand, if you take high sugar, it usually helps the bad bacteria growth like H-Pylori or E Coli. I was taking this advice and taking a lot of salads in these days.
Re: Antibiotics nearly double risk of developing IBD, doctors warn
#45Earlier quoted context omitted.
IBD is very different from IBS. IBD is an autoimmune disease with a pathologic diagnosis (ie requires a biopsy and microscopic evaluation for diagnosis). It’s treated as almost autoimmune diseases are. IBS is a syndrome (the S in the name) which usually implies a constellation of findings, but not a specific disease process. From the name you can know that the disease process hasn’t been clearly elucidated.
IBD is a catch-all for several different diseases, which are all poorly understood. There is still a debate over whether or not their cause is physical or psychological. There's a big gap between observing inflammation or related markers and actually understanding the disease. Even within the same subdiagnosis, people respond vastly differently to treatments, which more or less can all be described as intentionally c…
3 years ago I got diagnosed with IBS after I landed in the hospital with a stabbing pain just right next to my belly button (sometimes I still feel it lightly) what they first thought was caused by kidney stones. Nothing turned up on the xrays or echoes. Since then things have only gotten worse as if it has spread upwards first causing constipation, then silent reflux (causing a constant burning sensation in my throat, mouth and nose), pain in my neck, foggy brain (which started recently) and so on. The GP, which in my country decides if I have to be forwarded to a specialist to relieve the medical system, keeps attributing everything to my IBS. Once I got the diagnosis IBS it is as if they stopped taking me seriously and act as if I am just being a hypochondriac so I decided to just let it be.
Re: Antibiotics nearly double risk of developing IBD, doctors warn
#46Antibiotics cured my IBD. Had problems for years. A brief course of amoxicillin and some other, now forgotten, antibiotic (taken for unrelated reasons,) ended it almost immediately. It was amazing. What wasn't so good was catching C. diff. soon after, almost certainly because of the aforementioned antibiotics. Another treatment of yet another antibiotic dealt with that. Net result; no IBD.
Related: Antibiotics cured, for about a year, my severe gluten and corn intolerance. Then the gluten intolerance ame back. Ive gone through a few rounds of eliminating the gluten issues in this fashion, but the symptoms always return 10-16 months later.
You may have small intestinal bacterial overgrowth [1].
If you can't digest certain types of food, the bacteria which feed on this food grow out of proportion to their place in the microbiome. You'd often notice symptoms an hour or more after eating the food in question, which would give time for the food to hit the small intestine almost entirely undigested.
Taking antibiotics would kill off the overgrowth, but it would grow back over time unless you cut out the food or took supplementary digestive enzymes along with the food.
[1]: https://en.m.wikipedia.org/wiki/Small_intestinal_bacterial_o...
Re: Antibiotics nearly double risk of developing IBD, doctors warn
#47Ayurvedic practitioners always said stay away from western medicine, chemicals the rip out your gut and change your doshas.
Back in the day these good bacteria were found in milk, but now its homogenised and pastuerised they are killed off. THe reason we need to pastuerise the milk is to kill TB, but TB became more prominent after the industrial revolution.
Our demand for industralisation has created the mess we are in now.
Re: Antibiotics nearly double risk of developing IBD, doctors warn
#48Earlier quoted context omitted.
IBD is a catch-all for several different diseases, which are all poorly understood. There is still a debate over whether or not their cause is physical or psychological. There's a big gap between observing inflammation or related markers and actually understanding the disease. Even within the same subdiagnosis, people respond vastly differently to treatments, which more or less can all be described as intentionally c…
While I empathize with ibs sufferers, this is nonsense. Nobody with ibs poops large quantities of blood, needs their colon removed in many cases, or surgery because their bladder and bowel are now suddenly connected. We don’t fully understand most disease processes, even those for which we have some effective treatments. I don’t think lumping disparates diseases together simply on the axis of “understanding of diseas…
I think there are many more similarities between IBS/IBD than the current understanding of disease process. People IBS/IBD (especially mild IBD) have more in common with each other than folks with other chronic illnesses. For instance, your sibling comments story about seeking treatment for IBS is very similar to many IBD stories as well.
IBD is itself a lumping of disparate diseases based on very minimal understanding of disease process, so I'm not sure what your point is.
Re: Antibiotics nearly double risk of developing IBD, doctors warn
#49Earlier quoted context omitted.
IBD is a catch-all for several different diseases, which are all poorly understood. There is still a debate over whether or not their cause is physical or psychological. There's a big gap between observing inflammation or related markers and actually understanding the disease. Even within the same subdiagnosis, people respond vastly differently to treatments, which more or less can all be described as intentionally c…
3 years ago I got diagnosed with IBS after I landed in the hospital with a stabbing pain just right next to my belly button (sometimes I still feel it lightly) what they first thought was caused by kidney stones. Nothing turned up on the xrays or echoes. Since then things have only gotten worse as if it has spread upwards first causing constipation, then silent reflux (causing a constant burning sensation in my throa…
You might have success in managing symptoms by modulating diet and lifestyle. I personally find that a limited diet, no caffeine, and ample sleep help me a lot (I have Chrons), but every body is different.
Dealing with the medical system and outside advice in general can be very frustrating. Hope you can find a way forward! Good luck!
Re: Antibiotics nearly double risk of developing IBD, doctors warn
#50Earlier quoted context omitted.
IBD is a catch-all for several different diseases, which are all poorly understood. There is still a debate over whether or not their cause is physical or psychological. There's a big gap between observing inflammation or related markers and actually understanding the disease. Even within the same subdiagnosis, people respond vastly differently to treatments, which more or less can all be described as intentionally c…
3 years ago I got diagnosed with IBS after I landed in the hospital with a stabbing pain just right next to my belly button (sometimes I still feel it lightly) what they first thought was caused by kidney stones. Nothing turned up on the xrays or echoes. Since then things have only gotten worse as if it has spread upwards first causing constipation, then silent reflux (causing a constant burning sensation in my throa…
[IANAD] what you describe might as well be SIBO (as far as i understand in my limited non-professional understanding the bacterial overgrowth can cause the IBS symptoms too though fortunately i was spared that). It took some years in my case to stumble upon definitive test - the lactose based breath test - with all these years doctors dismissing it as "just take the antacid" (which is actually no-no for SIBO), and even with the definitive diagnosis confirmed by the test it is still a struggle to get a right doctor to correctly treat it.