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Challenges in the diagnosis of magnesium status

ncbi.nlm.nih.gov

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Re: Challenges in the diagnosis of magnesium status

#401

Post by binarypaean »

etaioinshrdlu wrote: post #84
wincy wrote: post #26

Earlier quoted context omitted.

Interesting. I recently started using Magnesium Glycinate as a supplement and I feel it truly changed my life, not exaggerating. I’ve suffered from chronic general anxiety for most of my teens and adult life. Magnesium has completely cleared this up, things I thought were just part of my personality (being anxious and other associated things) were actually due to a chronic magnesium deficiency. I just have to make su…

I have been heavy dosing magnesium (glycinate, citrate) for years and am still a nervous wreck. Your mileage may vary.

If you're interested in testing a further nutritional approach, I suggest the stack suggested by the late great Charles Poliquin.

The stack: https://www.facebook.com/StrengthSenseiInc/videos/anxiety-so... (sorry for FB link)

Background on Poliquin: https://tim.blog/2015/07/21/charles-poliquin/

Re: Challenges in the diagnosis of magnesium status

#402

Post by rojeee »

interlocutor wrote: post #262
kossTKR wrote: post #231

Earlier quoted context omitted.

How much magnesium are we talking about here? I actually have magnesium in my supplement drawer : "Magnesium Carbonate from natural sources" - it says take 2 grams, max 4 grams and let it "sit in cold water for 10 minutes, or warmer water for 10 seconds" before drinking. Is that the range you are taking and is the l-threonate form much better, ie. is carbonate useless? Interested in trying this out later this night..

The l-threonate works better for sleep. I take two 50mg tablets per day. In addition I take 400 to 600mg of "magnesium lysinate glycinate chelate" per day to help with muscles.

Thanks this is really helpful information. In your experience, is it a waste of time taking magnesium oxide for sleep?

Re: Challenges in the diagnosis of magnesium status

#403

Post by binarypaean »

coss wrote: post #307
wincy wrote: post #26

Earlier quoted context omitted.

Interesting. I recently started using Magnesium Glycinate as a supplement and I feel it truly changed my life, not exaggerating. I’ve suffered from chronic general anxiety for most of my teens and adult life. Magnesium has completely cleared this up, things I thought were just part of my personality (being anxious and other associated things) were actually due to a chronic magnesium deficiency. I just have to make su…

Wow, I started magnesium recently because of migraines. I’ve been twitching occasionally and I’ve been wondering why. Might just need more calcium. Thanks for sharing.

Because Magnesium and Calcium are both divalent the primary mechanisms of absorption tend to compete if you take them both together. You'll get higher bio-availability if you separate them in time (e.g. one with breakfast, the other with dinner).

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652077/

Re: Challenges in the diagnosis of magnesium status

#404

Post by binarypaean »

saiojd wrote: post #393
wincy wrote: post #26

Earlier quoted context omitted.

Interesting. I recently started using Magnesium Glycinate as a supplement and I feel it truly changed my life, not exaggerating. I’ve suffered from chronic general anxiety for most of my teens and adult life. Magnesium has completely cleared this up, things I thought were just part of my personality (being anxious and other associated things) were actually due to a chronic magnesium deficiency. I just have to make su…

Ok, your comment is shocking to me: I've been having annoying muscle twitches lately (probably from drinking lots of coffee), and one thing I found online was that magnesium supplements could help. I eventually ended up trying it, but the twitches just keep getting worse and worse; I didn't realize until now the magnesium is probably what is worsening things. Could anyone ELI5 what' the relationship between calcium,…

Your body has to move calcium ions in and out of (striated) muscles to trigger contractions. This is done through "calcium channels". Mg2+ is an antagonist to the activation of calcium channels.

You need enough calcium to achieve a strong reliable contraction, and enough magnesium to keep the channels "closed" when they should be closed (among very many other physiological uses).

In short, you need a balance of calcium and magnesium for reliable muscle function. A gross excess or lack of either is bad.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652077/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315934/

Re: Challenges in the diagnosis of magnesium status

#405

Post by cugs »

tekknik wrote: post #371
adsfasdfadsf222 wrote: post #334

Earlier quoted context omitted.

this is wat I eat, high calory, cheap, and very nutritious: breakfast: 6 raw eggs lemon juice (1 lemon, squeezed) 378 calories in total, of which 227 are fat and 144 protein. just enough sugar to help you digest it without bloat. awesome anabolic effects from the eggs. lunch: 6 raw eggs 200ml whole unhomogenised milk (raw if possible) similar effect but even more anabolic dinner: 200-300g of fresh steak (beef) cooked…

a dozen eggs a day and you’re getting what, 6x daily cholesterol intake?

Don't know how people are STILL concerned about egg intake. The science has been out for over a decade at this point.

https://onlinelibrary.wiley.com/doi/full/10.1111/j.1467-3010...

Re: Challenges in the diagnosis of magnesium status

#406

Post by QuantumGood »

treeman79 wrote: post #283
noodlenotes wrote: post #157

Earlier quoted context omitted.

I wonder if there's a relationship to the obesity epidemic, especially since it's not just humans that are getting larger but also lab animals, pets, and wild animals living close to humans [1]. What if we're compelled to eat more calories when we're not getting enough nutrients in our diets? This would impact any animals consuming lower quality fruits and vegetables. [1] https://www.nature.com/articles/news.2010.628

I was fat and had serious joint and muscle pain and major migraines. I started taking high levels of magnesium. My joints and muscles improved drastically. Migraines cut in half. I became able to exercise a lot more. I’m still fairly fat because I eat to much. Plus side effects of other medications. But I’m a lot stronger now since I can work out so much more. Best trick of all. Stop eating sugar / carbs.

That's great! Re: "high levels" Specifically how much?

Re: Challenges in the diagnosis of magnesium status

#407

Post by throwawaaarrgh »

xyzzyz wrote: post #327
kaitai wrote: post #318

Earlier quoted context omitted.

Agricultural policy in the US shapes a lot of this, though, via subsidies. The financial system also shapes this through its lending policies. The implements of industrialized farming are what the ag lending sector is designed around; try to step out of that mainstream and you will have trouble accessing capital. Wheat, corn, and soybeans are heavily subsidized by the US gov't and vegetables are not at all. Every lit…

That's because wheat, corn, and soybeans are staples, while vegetables are luxury food items, especially fresh ones. At no point in history, regular people in agricultural societies ate as much vegetables as we do right now. The diets has always been based in overwhelming majorities on grains, roots and beans, and in places with lactose tolerance, also on dairy. A single bell pepper today costs something between $1 a…

Corn and soy are not staples for humans, they're staples for industry. What doesn't get exported is used for livestock feed, ethanol, and filler for unhealthy foods. It makes a very small sector of our economy rich, it destroys huge swaths of our nation's ecology, and that result damages the health of animals (including us).

Feeding the nation isn't hard. We could feed this nation five times over with the amount of food we produce. The problem is, we'd probably shrivel up and die, because wheat, corn and soy aren't enough to keep a population healthy. We could actually produce more nutrition and calories with a fraction of the land just by switching from corn to oats. But then you'd be producing less, and hence selling less. That's not as profitable!

And vegetables are luxuries in the same sense that "nutrition" is a luxury. Just because humanity has historically had a shit diet (since the adoption of agriculture) doesn't mean it's a great idea to stop eating vegetables, or produce less of them. We get plenty of calories already - too many in fact. And most of the ones we do get are more harmful than good.

It would be better to get people to eat more of those low-calorie vegetables as it would help stem the American obesity crisis. And as we've seen in this report, vegetables already contain fewer nutrients than they did before - a reason to consume more of them, not less!

Re: Challenges in the diagnosis of magnesium status

#408

Post by cwp »

lamontcg wrote: post #394
cwp wrote: post #391

Earlier quoted context omitted.

I don't get it. You're saying we shouldn't bother to improve things because they still won't be perfect?

I'm saying we don't necessarily know good from bad and have fantastic amount of ignorance still about food and nutrition.

I got that part. So?

Re: Challenges in the diagnosis of magnesium status

#409

Post by saiojd »

binarypaean wrote: post #404
saiojd wrote: post #393

Earlier quoted context omitted.

Ok, your comment is shocking to me: I've been having annoying muscle twitches lately (probably from drinking lots of coffee), and one thing I found online was that magnesium supplements could help. I eventually ended up trying it, but the twitches just keep getting worse and worse; I didn't realize until now the magnesium is probably what is worsening things. Could anyone ELI5 what' the relationship between calcium,…

Your body has to move calcium ions in and out of (striated) muscles to trigger contractions. This is done through "calcium channels". Mg2+ is an antagonist to the activation of calcium channels. You need enough calcium to achieve a strong reliable contraction, and enough magnesium to keep the channels "closed" when they should be closed (among very many other physiological uses). In short, you need a balance of calci…

Thank you, this is interesting. It's kind of weird, realizing I don't understand my own body at all.

Re: Challenges in the diagnosis of magnesium status

#410

Post by tekknik »

cugs wrote: post #405
tekknik wrote: post #371

Earlier quoted context omitted.

a dozen eggs a day and you’re getting what, 6x daily cholesterol intake?

Don't know how people are STILL concerned about egg intake. The science has been out for over a decade at this point. https://onlinelibrary.wiley.com/doi/full/10.1111/j.1467-3010...

Probably because this article:

1) Doesn’t say it has no effect, it has “clinically insignificant especially when compared to saturated fat”. Not the same as no effect.

2) “ However, in the minds of the public, cholesterol in the diet, specifically from eggs, continues to be viewed with suspicion and that view is still reflected in the advice of some professionals.”

Professionals are still telling people to reduce cholesterol intake when your blood results show high cholesterol. How many people do you think spend every waking hour scouring for new health articles?

This is also just one study, maybe let’s not invalidate the many years of people reducing cholesterol intake to reduce cholesterol so quickly?

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