341–350 of 358 posts
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No, not suicide. Alcoholism, addiction to other drugs, car crashes, etc... Are all much more likely for untreated ADHD patients.
Yeah for real. I’m lucky I survived 3 car wrecks and that I’m not diabetic after years of compulsively consuming sugar to stimulate my brain. All got way better after I started being treated.
I have ADHD but know medication will turn me into an addict. I have experience and had to quit everything. It's better for me to live a mediocre life than to ruin what I have going for me. I've found habits and shaping the world around me is the best I can do.
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- Life being an eternal struggle due to slipping into drug/alcohol use and doing those very intensely - Being unable to maintain good habits (e.g. gym) because it feels like you're nearly a completely different person at different points because your desires/wants change from day to day to hour to hour to minute to minute - Forgetting literally everything due to getting distracted - Not remembering important stuff so…
I guess I have ADHD. I thought these were all normal things.
So this is basically Viloxazine, a drug no longer sold because it was unprofitable as an antidepressant, and now repurposed as a non-stimulant drug for ADHD. It appears to be cardiotoxic, working like a Tricyclic Antidepressant (TCA), yet less so than imipramine. It works by increasing levels of norepinephrine, altering some serotonin transmission, and maybe reducing some neurotransmitter release in the frontal corte…
It will most likely be "non inferior" to the standard of care, since that is the bar for new drugs to clear in any disease area. The issue with that designation is the FDA could compare it to stimulants or to the non-stimulant atomextine, which like Viloxazine is a norepinephrine reuptake inhibitor. Atomoxetine was preferentially used in those cases with added anxiety, since it was found to have anxiolytic effects. S…
Interestingly, Ritalin at low doses is being used at night to help ADD people sleep better. I think its because it keeps their minds from wandering too much when trying to fall asleep. Stimulants are also used to reduce anxiety in ADD people, but as you say, they may also increase it...double edged sword...guess each person has learn how to use it uniquely.
Seems that lots of people only think ADHD people have a hard time paying attention. If it was that simple I would be so happy. Here are just a few of the things I struggle with. - Will power. People with ADHD struggle sooooo much with will power. It’s a constant struggle with everything in life and really wears you down. - Constantly putting on a fake front pretending you don’t have ADHD. - Rejection sensitivity - Fe…
Why does no one focus on the positives? Yeah, there's shit to deal with but there are also lots of good points: * Ability to assimilate and process information * Ability to hyperfocus * Shit loads of empathy (can get a bit out of hand thought!) * Creativity There are lots more things that we're better at than non-ADD people, I just can't think of any at the moment! See Lynn Weiss' book for a more comprehensive list.…
Because the negatives massively outweigh any positives? I know that there are some authors who are trying to sell the idea of 'ADHD as a superpower' just like there are other authors who are trying to brand autism or even surviving cancer a 'superpower'. But just because an opinion is contrarian doesn't mean it's right. How else would you sell a book in a saturated market?
These 'positives' you mentioned are kind of useless when you can't steer the direction of your attention but tend to hyperfocus on random things that change ever so often.
If you can manage to somehow make a career out of it, more power to you.
Personally, I have tried to learn coding for over 20 years now. By now I have started over for dozens of times (Pascal, Delphi, VB, C, C++, Python, JS, Rust) and still I have zero to show for it.
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Yes just like SNRIs antidepressants so what is the difference? (stimulants also are dopamine reuptake inhibitors and low serotonine reuptake inhibitor) And no it does not cause the release of any monoamine, when they are released they can stay longer in the brain before being garbage collected which virtually increase their density. It is an unknown whether delayed this garbage collection cycle accelerate ageing or o…
The drugs you're talking about are classified NDRIs not SNRIs. Amphetamine is a releasing agent too. Different drugs have different receptor affinities. And the different metabolites do too.
Amphetamine is a releasing agent too good point but this additional aspect aside, dextroamphetamine should have the same antidepressant effect as Wellbutrin and I don't think that is the case, for an unknown reason.
Different drugs have different receptor affinities. Oh I thought Adderall was non-selective (affecting all receptors) but I might be wrong and that would be a possible explanation!
And the different metabolites do too. I don't know what this can imply.
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Yes just like SNRIs antidepressants so what is the difference? (stimulants also are dopamine reuptake inhibitors and low serotonine reuptake inhibitor) And no it does not cause the release of any monoamine, when they are released they can stay longer in the brain before being garbage collected which virtually increase their density. It is an unknown whether delayed this garbage collection cycle accelerate ageing or o…
No, sympathomimetics like amphetamines cause neurotransmitter release in addition to be reuptake inhibitors.
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> On the topic of Ritalin and Adderall, lots of my friends found they had to increase their dosage to see consistent effects. They are not addictive at normal doses but there can be tolerance depending on your diet. This is actually pretty easy to treat - get a lot more magnesium and try NAC as well. (Vyvanse's effectiveness actually seriously depends on how acidic your diet is. If you take a dose with orange juice i…
By the same logic cocaine in small doses would not be addictive. I can tell you that everything that manipulates your dopamin levels can lead to some kind of addiction. Plus you have actual withdraw symptoms from amphetamines too.
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By the same logic cocaine in small doses would not be addictive. I can tell you that everything that manipulates your dopamin levels can lead to some kind of addiction. Plus you have actual withdraw symptoms from amphetamines too.
It's so weird to keep hearing that prescription doses of these drugs are addictive. I regularly forget to take them until it's too late in the day and if I took them I would have trouble sleeping... :/
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The drugs you're talking about are classified NDRIs not SNRIs. Amphetamine is a releasing agent too. Different drugs have different receptor affinities. And the different metabolites do too.
I was incorrect in saying that stimulants are SNRIS, they are NDRIs as you say, however my point still stands. I don't understand the difference between e.g Adderall and Wellbutrin (which is an NDRI antidepressant) Amphetamine is a releasing agent too good point but this additional aspect aside, dextroamphetamine should have the same antidepressant effect as Wellbutrin and I don't think that is the case, for an unkno…
No 2 drugs are exactly alike. Their different metabolites also have their own effects.