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Israel’s Covid-19 boosters are preventing infections, new studies suggest

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Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#281
post #151
post #136

Earlier quoted context omitted.

> when it is now known that vaccinated people can still spread the virus Why wear your seatbelt if you can still die in a collision? Why bother with refrigeration when cold food can still rot? You can't think of risk in terms of binaries; bad things are still possible with the best safety technologies, but that doesn't mean those technologies aren't worthwhile. As an aside, the virus is actively changing over time, a…

> As an aside, the virus is actively changing over time, and delta variant is putting a lot more young people in the hospital. If this is the case, this is not hugely more than the previous variants as we can't see it on hospitalizations charts > Why wear your seatbelt if you can still die in a collision? Why not wear a helmet in a car I'm sure it would help in some cases ?

> Why not wear a helmet in a car I'm sure it would help in some cases ?

Race car drivers do wear helmets!

Risk-benefit is a simple matter of considering the relative downsides (costs) vs benefit (safety) of available options, and making some rational choices.

COVID is insanely dangerous. Even for young people, the dangers of COVID are directly comparable to professional car racing, base jumping, or similarly high-risk activities. For older people, it's comparable to being an astronaut. For people with co-morbidities, it's more risky than climbing Mount Everest!

Everybody undertaking all of those activities wears a ton of safety equipment. Did you notice?

Unfortunately, this kind of thinking has never worked for the general public, they always have to be dragged, kicking and screaming the whole way, every time.

My cousin drives his car with one hand past every traffic light with a safety camera, so that he can use the other hand to hold his seat belt near the buckle. This makes it look like it's clicked in securely, but obviously provide no safety beneft. This is insanely dangerous and much less comfortable than simply clicking in the seatbelt. (He drives a manual car, so he has to switch back and forth between the gear shift knob and the steering wheel rapidly!)

Why does he do this? Because "the man" is forcing him to wear the seatbelt, so it's a point of personal pride to refuse. "Gaming" the system by holding the seatbelt in the closed position without actually providing safety fills him with a sense of small accomplishment for having resisted the authorities.

I really wish I was kidding, but these are the kinds of thoughts that drive people to refuse to get vaccinated as well.

"No, I won't! The gubb'ment can fuck right off! I'd rather risk it and take Invermectin!" -- literally two of my friends, almost verbatim.

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#282
post #265

I was unaware Isreal repaired their relationship with Pfizer. Last I saw Israel was trying to stiff Pfizer for 2.5 million doses and Pfizer execs were calling Israel a 'banana republic' and were going to cut them off entirely.

Citation needed

https://www.insider.com/pfizer-halts-shipment-of-covid-vacci...

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#283
When will we stop seeing this vague click-baity titles? "new studies suggest" - not conclusive.

"Protection increases in the weeks following a third dose, but it’s unclear how long the effect will last"

"by more than 10-fold 2 weeks later."

After the first paragraph, it was only established that it provides short term immunity against Delta variant. How long will it last? How well will it do against other variants? Also, the demographic receiving booster shot in Israel are mostly elderly. So this impressive infection rate drop was observed only in older demographic. The effect probably won't be as good among younger generations. Repeated vaccination adds more risk, even if it is small per dose, it is being accumulated. Can we keep up with booster shots every six months? Even flu shot is only once a year and choosing next year flu shot strain is a year long challenge.

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#284
post #64

Earlier quoted context omitted.

> Is there any reason not to increase vaccine production rates so we have the capacity to vaccinate the world population faster than every 9 months? Capital constraints. Most specifically, human capital. mRNA production methods, including for critical precursors, are complicated. There is a limited number of people who can build and monitor the productions systems.

There are countries filled with idiots,like my lovely Romania where 70% of people don't want to get vaccinated, and we have to sell/donate millions and millions of doses.

Well, that's only partially true. Romania has preordered 120M doses for (at best) 15M eligible people. So either way, we'll have to donate tens of millions of doses.

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#285

Earlier quoted context omitted.

I have never ever on HN seen an argument about DNA and mRNA, but then again I don't follow the conversation too much. As it seems like you know someone with correct background on the subject, so I wanted to ask you something I've always wanted to know as a young,(late 20s) healthy person with no existing risky precondition in this pandemic: Why should I take a vaccine, when it is now known that vaccinated people can…

Think of it this way, you have two choices: 1. You have a 0.0001% risk of death, and a 0.001% risk of hospitalization, and will maybe spread covid to 5-8 people. Long term effects unknown. 2. You have a 0.00001% risk of death, and a 0.0001% risk of hospitalization, and will maybe spread covid to 1-2 people. Long term effects unknown. Which choice would you take? (note the 2nd option is a conservative estimate of the…

you forgot to add an important argument: You forget to say that probably both are manmade.

Who do you trust more? 1) something probably created in a chinese lab? 2) something created by a list of different corporations and tested independently by at least 50 countries?

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#286

I'm pretty surprised to still see some misinformation in some of the posts here. I have a friend who has a PhD in molecular biology and she described the mRNA vaccines to me. The mRNA is only a piece of the spike protein, and does not enter the cell's nucleus. It only interacts with the cytoplasm. Normally, if a cell had to deal with an actual SARS-CoV-2 virus, it would be dealing with the spike proteins and the enti…

Since you are describing the ingredients of an mRNA vaccines, here is an illustration by David Goodsell.

https://pdb101.rcsb.org/sci-art/goodsell-gallery/sars-cov-2-...

Check the rest of the site, he does awesome watercolor illustrations of microbiology. Including of the SARS-CoV-2 virus itself ( https://pdb101.rcsb.org/sci-art/goodsell-gallery/sars-cov-2-... )

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#287
post #8

I am fascinated to know what the effects are of over-vaccination. Is there some spillover effects where a highly-primed immune system begins to get into weird autoimmune reactions? Do weird plaques develop or a build-up of antibodies begin to form in random parts of the body, like in a blood dyscrasia? Or does nothing happen? Chronic vaccine overdoses are so exotic, as access to vaccines had been historically so tigh…

> Do weird plaques develop

> build-up of antibodies begin to form in random parts of the body

Real curious: do these things exist in the first place ? Plaques of what ? Where in the body ?

I've never heard of antibody build up and google neither apparently

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#288

It's like Linux on the desktop and fusion reactors. It seems like we are always one jab away from being safe and overcoming covid.

If you think that's fun, imagine the steady state being like flu - monitoring Covid variants, then trying to predict which ones will be the next "wave".

Some years you'll get it right and put a big damper on spread and some years you'll pick the wrong variant leaving most people unprotected.

That's one reason why flu deaths in the US fluctuate annually (in addition to the severity of the flu). A few years back the vaccine basically did nothing.

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#289
post #75
post #18

Earlier quoted context omitted.

Oh, we have acknowledged it. The question is, have our politicians acknowledged it, or will they keep taking our rights?

Try going out in public naked or running a few red lights and then come back and troll some more about your "rights". The world is full of rules to prevent you from being a jerk and endangering others.

Your argument comes down to "we limit your rights in other ways, so limiting your rights in this way should be accepted".

That's not a very convincing argument - it could be applied to anything. "We force you to show ID to fly on a plane, so being forced to show ID to access the internet should be accepted".

Re: Israel’s Covid-19 boosters are preventing infections, new studies suggest

#290
post #36

It's like Linux on the desktop and fusion reactors. It seems like we are always one jab away from being safe and overcoming covid.

There is no such thing as safety, only varying degrees of risk. Everyone has a different risk tolerance. Failure to explicitly quantify acceptable risks leads to people making invalid assumptions and talking past each other.

This is very true - I remember a colleague getting slapped down by the FDA when he said his company's FDA-approved drug was "safe". "There is no 'safe' drug", he was told, "only acceptable risk-benefit tradeoffs".

In addition, what is acceptable on a national level (e.g. 50 deaths from vaccination side effects) may not be acceptable on a individual basis (e.g. you die from a vaccine side effect).

Just like people dismiss the risk of Covid until it kills a family member, the flip side is people dismiss the risk of vaccination until it kills a family member.

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