It's unlikely popular and profitable services will be hindered by the lack of net neutrality. But any new services that threaten existing ones will be hard-pressed to compete. Imagine I start a new streaming service. In order for my service to reach people, ISP's will charge me a higher price than Netflix, probably a _significantly_ higher rate. This will make it extremely difficult for my new service to reach enough…
"Amazon EC2 and S3 now include prioritized traffic to the network edge through Amazon's deals with over a hundred local and regional ISPs. Just add traffic priority to any elastic IP or S3 bucket and for only $0.04/gb outgoing your traffic will take the fast lane to your customers!"
How will Digital Ocean, Vultr, ARP Networks, Linode, etc. compete with that?
What we're seeing here is the closing of the digital frontier.
That being said my personal preference is not for net neutrality but for changes to state and local regulation to allow for a lot more ISP competition. But due to the patchwork nature of state and local regs that's a brutal slog in the trenches. So we need net neutrality in lieu of more ISP competition. Either that or we need to somehow overrule state and local regs at the Federal level to allow municipal and small startup broadband. That's tough given the fact that the Fed doesn't necessarily have any authority there. They'd have to argue it's interstate commerce.