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Pfizer’s Covid-19 Pill is 89% Effective in Phase 2/3 Study

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Re: Pfizer’s Covid-19 Pill is 89% Effective in Phase 2/3 Study

#221

Post by tommit »

ohiovr wrote: post #216

Sure are a lot of missing comments here. It seems hardcore leftists love diversity in everything except diversity of opinions. Ah this place is basically group think extreme. More interesting than Reddit usually but just as hostile to debate about subjects that go against the TV gods or popular culture. Basically the internet is becoming little clicks of people that dare not even speak up for fear of losing more than…

What are you on about? And how is this comment at all contributing to a healthy discussion?

Re: Pfizer’s Covid-19 Pill is 89% Effective in Phase 2/3 Study

#222

Post by johnisgood »

CydeWeys wrote: post #118
Msw242 wrote: post #108

Earlier quoted context omitted.

There are allergies to vaccines (not to the dose, but to everything else that is in the concoction that enables it to work). Also, immunocompromised people often can't take vaccines. Usually you can get a doctor's note explaining this, and you can participate in daily life normally (like going to school or college, which rightfully require vaccinations). I don't know if policy around the COVID vaccine is different...…

> Also, immunocompromised people often can't take vaccines. Nope. Immunocompromised people need extra doses of the vaccine, and even then it doesn't work as well. This is one of those false talking points that antivaxxers love to spread.

Being immunocompromised is a contraindication around here. That said, only as so far as you are, for example you are on a corticosteroid therapy.

Re: Pfizer’s Covid-19 Pill is 89% Effective in Phase 2/3 Study

#223

Post by johnisgood »

mlyle wrote: post #189
CydeWeys wrote: post #185

Earlier quoted context omitted.

In all these cases, though, the immunocompromised person who is not greatly benefiting from the vaccine is at much greater risk of dying from COVID. The sane response for them is to be very very careful about any potential exposure, NOT to get exempted from the vaccine requirement and then go do insanely risky face-to-face activities that otherwise would have a vaccine mandate. My friend is immunocompromised from che…

> In all these cases, In the second case, the person choosing the vaccine has a high risk of, say, a debilitating RA flareup and an uncertain amount of protection given their immunocompromised status. I can totally understand why some in this position choose not to. They probably should , but this is not as clear-cut of a decision as for those of us with normal immune capability. No one knows the exact efficacy they…

> because vaccines can kick up immune and inflammatory responses and make their conditions worse

This is what I am really worried about. If my immune system is poked even so slightly, I get symptoms although not as bad as I imagine I would get after the vaccines. I already have mobility issues. I do not want to be wheelchair-bound, even though that is a very likely outcome anyways.

Re: Pfizer’s Covid-19 Pill is 89% Effective in Phase 2/3 Study

#224

Post by johnisgood »

sudosysgen wrote: post #83
johnisgood wrote: post #53

Earlier quoted context omitted.

But I am not vaccinated for health reasons. When are we going to start differentiating? Were I not a freelancer, I would have lost my job because I am not vaccinated, for health reasons. It is a pretty shitty thing to do to people.

At least where I live, if you cannot get vaccinated for health reasons you will be considered as if you were vaccinated.

That sounds good. Someone commented that my employer is supposed to consider the contraindication and whatnot, but it really is not the case, at least not as far as the law goes. My employer could consider it, but does not have to. I am going to the dentist and I need a negative PCR test every 48h, and it is expensive. :/

Re: Pfizer’s Covid-19 Pill is 89% Effective in Phase 2/3 Study

#225

Post by stunt »

It doesn't help that public is too sensitive about this subject. Government can't scrutinize companies like Pfizer enough if they are worried about public reaction. And I'm not too surprised if some companies rush since a lot of money is on the table.

To be fair, this is the best effort we have ever had to develop a vaccine. So I don't think it's fair to blame these companies if their vaccine wasn't effective on new variants as they initially promised. But that doesn't mean that we shouldn't thoroughly scrutinize them.

Re: Pfizer’s Covid-19 Pill is 89% Effective in Phase 2/3 Study

#226

Post by epgui »

refurb wrote: post #218
epgui wrote: post #196

Earlier quoted context omitted.

Driving Rt below one will cause any species to go extinct. That’s just basic maths. If it’s not happening, then Rt is not below 1. As for the rest, you’re taking ideas that have some truth to them, and probably misinterpreting what these things actually mean and taking them unreasonably far or to the extreme: - Herd immunity is a thing, but I'm not sure how you imagine it in your head, or what you think that means. -…

Your response is some impressive hand waving. Yes, those things are infectious disease concepts and they were touted as to how COVID will be dealt with. Lots of talk of “once we get to 80% vaccination rate we’ll hit here immunity”. You don’t hear that any more huh? “If we drive R below 1 we can extinguish Covid”. Now it’s “Covid is endemic, it’s not going away”. “Once everyone is vaccinated, Covid goes away”, then “I…

My response isn’t hand-wavy, it’s pretty categorical: the problem is that people can’t deal with uncertainty, and fill in too many blanks in their minds with over-simplistic assumptions. If you’re looking for a full picture of certainty about the future, that’s not exactly what science will give you.

Re: Pfizer’s Covid-19 Pill is 89% Effective in Phase 2/3 Study

#227

Post by anaganisk »

refurb wrote: post #219
anaganisk wrote: post #215

Earlier quoted context omitted.

Or your understanding skills are weak. I don’t know what you are even trying to reply, I don’t see one mention that says CDC claims vaccinated people do not spread the infection. Yes they said rarely, but that does also mean, vaccinated people are likely to spread disease. Unlike your statement earlier which implies they claimed vaccinated do not spread disease.

So you agree that the CDC was wrong? That was my entire point and what you challenged me on. You seem to be trying to squirm out of your earlier statement.

No expert worth his salt will ever say vaccines are 100% effective, what vaccine does is train your body, its up to your body on response. So what CDC said was true, I never said it was wrong. You took the article as an absolute statement which is clearly wrong.

Re: Pfizer’s Covid-19 Pill is 89% Effective in Phase 2/3 Study

#228

Post by acdha »

refurb wrote: post #217
acdha wrote: post #207

Earlier quoted context omitted.

The problem was that it was politicized hard early on. Now you have roughly a third of the country who’ve been told that public health measures are an unpatriotic plot, and a lot of belligerence had been encouraged. The rhetoric around this made it a very clear party loyalty test and lots of people rose to that challenge. How many people are willing to admit that they were so wrong for the better part of two years an…

I’ve spent months in 4 different countries since Covid hit and it’s politicized everywhere . Not sure how you can force people to stay at home, kids out of school, then hand out billions in relief (or not in one country) and not have it be political?

I was specifically thinking about the politicization of protection and treatment. The economic impact was definitely always going to be a debate but basic safety measures like masks and vaccination didn’t used to be a strongly partisan issue (think about how American doctors historically leaned Republican for tax reasons).

Different countries matter less in the internet era, too. In the English-speaking world, the Murdoch media set the message in the US & UK, of course, but these days that spreads quickly outside of national borders and it was easy to see those messages jump to other language communities on social media. This was especially accelerated by the early recognition of certain risk factors which were compatible with the strong man posturing common to a lot of right-wing ideology.

Re: Pfizer’s Covid-19 Pill is 89% Effective in Phase 2/3 Study

#229

Post by spurgu »

epgui wrote: post #196
refurb wrote: post #187

Earlier quoted context omitted.

- herd immunity - driving R-value below 1 will cause Covid to extinguish itself - vaccine will prevent infection - vaccinated can get infected but don’t really infect others

Driving Rt below one will cause any species to go extinct. That’s just basic maths. If it’s not happening, then Rt is not below 1. As for the rest, you’re taking ideas that have some truth to them, and probably misinterpreting what these things actually mean and taking them unreasonably far or to the extreme: - Herd immunity is a thing, but I'm not sure how you imagine it in your head, or what you think that means. -…

R0 < 1 should be measured globally unless you're planning on isolating forever.

Re: Pfizer’s Covid-19 Pill is 89% Effective in Phase 2/3 Study

#230

Post by spurgu »

epgui wrote: post #214
disambiguation wrote: post #213

Earlier quoted context omitted.

That's what I thought.

All the behaviour changes, vaccines, masks and other public health intervention have the effect of reducing Rt, geometrically, by some factor. When Rt goes below 1 for long enough, not only do variants go away, covid goes away. When you do all kinds of halfass measures and either Rt does not go below 1, or keeps going below and above 1, then you’re giving time for the virus to mutate, and this has the effect of movin…

So what do you do when variants are still ravaging in Africa for example? Isolate the continent?
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