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Intermittent fasting from dawn to sunset induces anticancer response

pubmed.ncbi.nlm.nih.gov

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Re: Intermittent fasting from dawn to sunset induces anticancer response

#221

Post by manicorganic »

airstrike wrote: post #70
rsync wrote: post #66

Earlier quoted context omitted.

"Would really like to see this compared to another group with a similar level of calorie restriction but without the intermittent fasting." I think the answer to your question is total time inflamed (for lack of a better term). Eating and digesting appear to be an interrupt for many other processes, for obvious reasons. You divert a lot of resources and produce a lot of inflammation and depress a lot of immunity. Do…

Whereas my bro-science intuition tells me that asking my pancreas to produce all the insulin I need in a tighter window is much more taxing

A single, giant meal is not going to be associated with the problematic blood sugar spikes and rapid insulin responses as long as it is a balanced meal that includes a good amount of fats, proteins and vegetables. All of these slow digestion, so the pancreas will be doling out insulin at a relatively steady, slow rate over the course of hours and then getting a nice long rest.

Eating 3 balanced meals throughout the day might be marginally better or worse for the pancreas, but neither of these dietary choices trigger the panic-level insulin responses (which ultimately lead to insulin resistance and diabetes) that snacking on large amounts of refined carbs and refined sugars are notorious for.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2121099/ This study found that although there was higher blood glucose and reduced glucose tolerance in the morning for the group eating 1 meal a day, surprisingly they had less insulin resistance than the group eating 3. Other indicators of dietary/hormonal health were the same between groups. Same caloric intake of glucose between groups, and the 1 meal a day group shared the same evening window just like OMAD. This was a pilot study with small sample size (irritatingly the actual number isn't listed from what I can see) as well as a high withdrawal rate, unsurprisingly.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#222

Post by kimi »

fragsworth wrote: post #212
kimi wrote: post #188

I'd say this - while interesting - does not show a thing. It happens that a billion or so people do this every year, so any actual public health effect should be quite noticeable. Instead, "the highest percentage change in age-standardized BMI related deaths and disability-adjusted life-years occurred in Bangladesh" (that is mostly a Sunni country) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866840/#Sec3ti... Or…

If you're referring to Ramadan, I don't believe that's the same thing, because it is two meals a day, spaced apart significantly, and only lasts a month. I also question religious devotees adherence to their religion. There are no stats on it and it is impossible to measure... Perhaps a significant number of them secretly cheat.

This study is exactly Ramadan, by design (but it does not say so in the title).

In fact one of the recruiting rules was "2) Subjects who plan to fast during the religious month of Ramadan" and therefore "All subjects fasted for more than 14 h daily for 29 days beginning from May 06, 2019, until June 03, 2019".

See full text https://www.nature.com/articles/s41598-020-73767-w

Re: Intermittent fasting from dawn to sunset induces anticancer response

#223

Post by [deleted] »

fauigerzigerk wrote: post #208
JacKTrocinskI wrote: post #173

I don’t think you should be looking at studies when it comes to how you eat, you should be focusing on how you feel, observing your own body and possibly talking to a doctor. I had a really big problem with acid reflux a while back after I stopped drinking alcohol. I visited many gastrologists and most of them offered little to no help, most only prescribed me drugs which was in my opinion not a solution. I finally m…

> I don’t think you should be looking at studies when it comes to how you eat, you should be focusing on how you feel Why not do both? I don‘t see how one can ever be a substitute for the other.

[deleted]

Re: Intermittent fasting from dawn to sunset induces anticancer response

#224

Post by manicorganic »

rsync wrote: post #189
airstrike wrote: post #70

Earlier quoted context omitted.

Whereas my bro-science intuition tells me that asking my pancreas to produce all the insulin I need in a tighter window is much more taxing

I don't know. You're talking about the engagement of the pancreas itself and I am talking about the effects of that engagement on the entire body. I note with interest that we make reference to insulin "spikes". Do I want to insulin spike more, or fewer, times per day ?

Ideally you want no spikes, because you are eating a balanced diet and avoiding meals and snacks consisting largely of refined carbs and refined sugars. A proper meal shouldn't really create a blood sugar (and resulting insulin) spike as much as a gradual elevation and fall back to baseline, because protein, fat, and fiber all slow digestion, and complex carbs (and even sugars within fiber/nutrient matrixes ie whole fruits) don't tend to spike blood sugar too badly in the first place.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#225

Post by bashwizard »

azemetre wrote: post #41
mrapogee wrote: post #25

Earlier quoted context omitted.

True. However, even if intermittent fasting is no more effective than calorie restriction, from a human behavior perspective, it seems to be an easier way for many people to achieve their calorie goals than just "eating less".

Yeah, this is why I prefer one mead a day (OMAD). It's a very large meal, 1600-2000 calories over a 2 hour period but I find it much easier to control my calorie intake this way. The only thing I regret since the pandemic is drinking coffee. I try to limit the amount of sugar and almond milk I add, but I feel like it's impacting my diet some how.

If you add anything to your coffee you're in fact breaking your fast so you're not really intermittent fasting any more.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#226

Post by jelliclesfarm »

azifali wrote: post #87

I do this every year as a part of Ramadhan. Though I am not very religious - fasting and taking a break from the usual each year is uplifting, deeply spiritual and of course has health benefits..

A slightly different perspective from another religion. I am trying to follow the Hindu Lunar calender. But it’s a 2 week schedule based on full moon and new moon.

Basically on the 11th day after full moon and new moon, one fasts from sunrise to sunset. That’s twice a month. It’s called Ekadasi Fast.

But the real trick is preparing to fast 6-8 hours before and after the day of the fast.

Also the day after the fast, the food has to be grain/gluten free(rice seems to be ok) and has certain ingredients like greens, herbs and spices. It’s very light.

Full moon and new moon days are always food for milk and fruit fasts. And there is a whole bunch of other religious day fasts. Example: no salt on 6th day after full/new moon..a lot of ingredient restrictive fasts etc. I don’t know a lot about that but I have seen my mother observe it. I must find out more.

There seems to be a whole method to the madness and when scheduled properly, one can do staggered and scheduled partial fasts 6-7 days for a lunar fortnight. The calorie restriction mostly comes from the rules against certain ingredients.

Even in the pared down format I follow, I feel like I connect more with my food and am more mindful when I cook. Most of all, I don’t waste as much food because it’s so much work preparing the food! Of course, it’s seasonal. Having said that, I guess annual menu and schedule format has to be reversed for those in the Southern Hemisphere.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#227

Post by saiya-jin »

Melting_Harps wrote: post #111
peteretep wrote: post #103

Earlier quoted context omitted.

> Anxiety I often offset with significant amounts of CBD (a $100/month expense). While I wouldn’t dare to comment on someone else’s mental health situation, I’d note for anyone else reading and considering this that traditional SSRIs are very effective for some people, cheap, and you won’t have trouble taking them across borders or getting them prescribed in an emergency from a random doctor if you lose your stash

> traditional SSRIs are very effective... With immense amount of side-effects, I'd advise people to use CBD to see if it alleviates the symptoms before any SSRI. In addition to the anxiety, I needed it for inflammation and pain relief which is a massive component to many ailments that have compounding effects. I worked 70+ hours a week in the peak season(s), so sleeping became a rare commodity which high loads of CBD…

You sounds like living within extremes in quite a few aspects of life. Feels like some underlying (mental?) condition from description that manifests as anxiety. Ever thought about getting deeper instead of trying to fix the effects of such a behavior?

Re: Intermittent fasting from dawn to sunset induces anticancer response

#228

Post by ElijahLynn »

JacKTrocinskI wrote: post #173

I don’t think you should be looking at studies when it comes to how you eat, you should be focusing on how you feel, observing your own body and possibly talking to a doctor. I had a really big problem with acid reflux a while back after I stopped drinking alcohol. I visited many gastrologists and most of them offered little to no help, most only prescribed me drugs which was in my opinion not a solution. I finally m…

You can't "feel" if you have cancer or not, until it is too late.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#229

Post by egman_ekki »

Barrin92 wrote: post #102
ronyeh wrote: post #32

Earlier quoted context omitted.

I think intermittent fasting is easier to implement for the average person. It's much easier to tell someone that they can eat as much as they want, but only between 6-8pm (one meal a day). It's difficult to tell someone you can eat 3 meals but no more than 1500 calories in total. Once I start eating, I don't want to stop (until I'm full). But the point at which I'm full is way beyond my calorie limit if I am eating…

>It's much easier to tell someone that they can eat as much as they want, but only between 6-8pm (one meal a day). If eating is part of your social or work life as it is for most people then not really. Or you're going to sit there sipping water while your family or your colleagues eat or have drinks which is miserable

> 14 subjects with metabolic syndrome who fasted (no eating or drinking) from dawn to sunset for more than 14 h daily for four consecutive weeks

it says no drinking as well, so not sure about the water, but I was surprised to read it, maybe they just meant drinks other than water.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#230

Post by random_savv »

tomcooks wrote: post #197
theshrike79 wrote: post #185

Earlier quoted context omitted.

The problem with this, for too many people, is that they've never felt "good". They don't have a point of reference they could use to guide them to a better lifestyle They only know the right-now and that's good enough for them. This is something I've seen with my friends and family who have never been in good shape. They don't know that it's possible to go up 3 flights of stairs 2-3 steps at a time at a brisk pace a…

> fart 24/7 The article is about intermittent faSting

underrated response! :-)
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