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Intermittent fasting from dawn to sunset induces anticancer response

pubmed.ncbi.nlm.nih.gov

61–70 of 388 posts

Re: Intermittent fasting from dawn to sunset induces anticancer response

#61
post #35

No control group, and n=14. This study says nothing.

"Nothing" is a bit strong – it probably says that further study is warranted. It certainly doesn't say that intermittent fasting will cure/prevent cancer.

Since I believe this is religious fasting, the subjects probably didnt smoke during the day. Question is of course how many smokers are there in the group.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#62

Earlier quoted context omitted.

True. However, even if intermittent fasting is no more effective than calorie restriction, from a human behavior perspective, it seems to be an easier way for many people to achieve their calorie goals than just "eating less".

Yeah, this is why I prefer one mead a day (OMAD). It's a very large meal, 1600-2000 calories over a 2 hour period but I find it much easier to control my calorie intake this way. The only thing I regret since the pandemic is drinking coffee. I try to limit the amount of sugar and almond milk I add, but I feel like it's impacting my diet some how.

With regards to coffee, you can try cold brewing coffee, it's much smoother (less bitter and less acidic), which might allow you to drink it without sugar and milk. There are commercially available cold brew coffees that have no added sugar and milk as well, in case you want to try the taste before making it at home.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#63

Earlier quoted context omitted.

True. However, even if intermittent fasting is no more effective than calorie restriction, from a human behavior perspective, it seems to be an easier way for many people to achieve their calorie goals than just "eating less".

Yeah, this is why I prefer one mead a day (OMAD). It's a very large meal, 1600-2000 calories over a 2 hour period but I find it much easier to control my calorie intake this way. The only thing I regret since the pandemic is drinking coffee. I try to limit the amount of sugar and almond milk I add, but I feel like it's impacting my diet some how.

As someone who absolutely needed sugar in coffee before I considered it drinkable, I can tell you that you can wean yourself off it. It took me several months before I stopped noticing its absence but nowadays I don’t miss it. I still use milk though!

Re: Intermittent fasting from dawn to sunset induces anticancer response

#64
post #49
post #39

Earlier quoted context omitted.

> until I'm full and I've learnt that it's very hard to know when you're satisfied in terms of hunger, and full in terms of desire. The level of food required to satiate my hunger seems to be quite different from when I am "full".

The more you are used to eating in an average meal, the longer it takes to feel "full".

Also, it takes time for the chemical reactions in your body to tell you you are full, so if you eat a little bit, and stop for 15 min, you might very well find that you are full.

However, once the taste buds are firing, it’s pretty hard to stop eating mid meal. One way is to take a little bit of food away from all the other food, eat it, and then force yourself to sit there while your blood sugar catches up to tell you if you still need more.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#65

Anecdata: I have followed IF with a 1100 calorie deficit per day by only eating 1200 calories at dinner for 3 months. This translated to more than 1kg weight loss per week, pretty reliably. Overall I lost 17kg. I adjusted the TDEE and calorie values as needed to maintain the weight loss speed. The weight loss was extremely fast, but so was the rate at which I lost lean mass. This makes sense, as I didn't exercise muc…

Yeah, fasting is one of those ""health fads"" that really does seem to work miraculously... for some people. For some, it's just nothing; for some, it's miserable. Kind of bizarre how different our metabolisms can be.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#66
post #9

> Subjects had a significant reduction in body mass index, waist circumference, and improvement in blood pressure Would really like to see this compared to another group with a similar level of calorie restriction but without the intermittent fasting. The question with intermittent fasting is really just "is it better than plain old calorie restriction". Seems like there's some evidence that points to "yes" and some…

"Would really like to see this compared to another group with a similar level of calorie restriction but without the intermittent fasting."

I think the answer to your question is total time inflamed (for lack of a better term).

Eating and digesting appear to be an interrupt for many other processes, for obvious reasons. You divert a lot of resources and produce a lot of inflammation and depress a lot of immunity.

Do you want to be in that state for 14 hours per day or for 6 hours per day ?

My bro-science intuition tells me that, all else being equal, consuming the same number of calories in a tighter window is much less expensive.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#67
post #53

Also recommended, stretching your low back five times a day.

In what way? Do you have a lower back routine?

I believe he's humorously referring to how Muslims already do this by praying five times a day. The routine requires prostrating multiple times, therefore stretching your back :)

Re: Intermittent fasting from dawn to sunset induces anticancer response

#69

No control group, and n=14. This study says nothing.

Generally it's good to be skeptical but this- "We found a significant fold increase in the levels of several tumor suppressor and DNA repair gene protein products (GP)s at the end of 4th week during 4-week intermittent fasting (CALU, INTS6, KIT, CROCC, PIGR), and 1 week after 4-week intermittent fasting (CALU, CALR, IGFBP4, SEMA4B) compared with the levels before 4-week intermittent fasting." But why would this sudde…

Is it climate change? Is it because the stock market went up 10%? Because Saturn's orbit crossed it's periphelion? Or more seriously, could it just be the Hawtorne effect?

As you pointed out, without a control group, you cannot claim that any change in your measurements are due to anything. The fact that the researchers do attribute it to fasting is just bad science and makes me doubt the rest of their findings.

Re: Intermittent fasting from dawn to sunset induces anticancer response

#70
post #66
post #9

> Subjects had a significant reduction in body mass index, waist circumference, and improvement in blood pressure Would really like to see this compared to another group with a similar level of calorie restriction but without the intermittent fasting. The question with intermittent fasting is really just "is it better than plain old calorie restriction". Seems like there's some evidence that points to "yes" and some…

"Would really like to see this compared to another group with a similar level of calorie restriction but without the intermittent fasting." I think the answer to your question is total time inflamed (for lack of a better term). Eating and digesting appear to be an interrupt for many other processes, for obvious reasons. You divert a lot of resources and produce a lot of inflammation and depress a lot of immunity. Do…

Whereas my bro-science intuition tells me that asking my pancreas to produce all the insulin I need in a tighter window is much more taxing
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