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Long Covid: major findings, mechanisms and recommendations

nature.com

191–200 of 229 posts

Re: Long Covid: major findings, mechanisms and recommendations

#191
post #4

Unease and woe are the two feelings I'm left with after my quick layman reading of the article. Think I am most concerned with the reproductive implications, which seem under researched. Coupled with the unrelated decline in sperm count the past decade... I'm hoping my ruminations are just me catastrophizing. Can anyone more medically and scientifically literate provide some context to temper my doom and gloom?

assisted reproduction exists for many decades and works well

Re: Long Covid: major findings, mechanisms and recommendations

#192

Earlier quoted context omitted.

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Shoutout to the British NHS Data that lists for risk of hospitalization/overnight hospitalization /dying per agegroup(decade each) per month.

I find it worth mentioning that the conscious choice not to do this and argue with overall numbers is clearly showing a lack of integrity in the source aimed at pushing a predetermined narrative.

You can not in good concise pretend or even imply that this an evenly distributed risk. Be it among agegroups, comorbidities or among the time axis since the start of the pandemic.

And to give some food for thought, people will reliably overcorrect to adapt for that distortion in their sense making process. Its how a justified loss in credibility looks like and influences peoples behavior.

Re: Long Covid: major findings, mechanisms and recommendations

#193

Earlier quoted context omitted.

I stand by what I originally said. It seems like you are misinterpreting it somewhere along the line but what I said is backed by fact. Again, check the source I linked. It is verifiably true that the death rate of covid is 1.1% in the U.S. Do you have a different definition of "death rate"? > now admit it is at least 5-10x lower Never did I say anything to this effect. So who is really arguing in bad faith?

Come on you don’t even know the definition of IFR? Seriously. You linked to CFR data yet frame it as IFR, this is like an amateur level discussion if we are back to discussion IFR and CFR. I don’t even know where to start if that is where we are at.

>I don’t even know where to start if that is where we are at.

I have been thinking about this a bit, i believe the pandemic (and this conversation) has been a great example for the general limits of distributed sensemaking and how it breaks down at communicating (and capsuling) all the relevant aspects and perspectives to a topic or statement.

I think in the end everyone has their map of the problem and we are failing (due to the limited bandwith of speech and text among others) at comparing why they differ where. Be it incomplete data, overlooking important perspectives or simply cognitive biases/ ego induced (not wanting to be wrong, tribalism...) errors.

Would you agree?

Re: Long Covid: major findings, mechanisms and recommendations

#194

Earlier quoted context omitted.

The VA is almost nothing but old sick people, the demographic most susceptible to serious COVID. Fortunately, most of the population isn't old sick people. The study you reference isn't relevant to conversations about the general population. The view that risk from subsequent infections is negligible is informed by the fact that vast numbers of people have had subsequent infections , including most of the people they…

> The VA is almost nothing but old sick people, the demographic most susceptible to serious COVID. On the other hand, that someone served in the military means they were healthy enough to get in. Those with serious defects never get to the VA.

Also, pediatric long COVID is real and not rare.[1]

[1] https://www.cnn.com/2023/01/14/health/long-covid-children/in...

Re: Long Covid: major findings, mechanisms and recommendations

#195
post #175

Earlier quoted context omitted.

Seems like long COVID and CFS are being conflated here.

Not really, they're basically the same thing. Except hopefully you (eventually) recover from long covid. If you don't recover, it's medically indistinguishable. Like CFS, "pushing through" can worsen symptoms - permanently.

One very troublesome aspect of that stats is that changes to sense of smell are tracked as long COVID.

It quite invalidates the figures

Re: Long Covid: major findings, mechanisms and recommendations

#196

Earlier quoted context omitted.

He who laughs last, laughs best. Keep laughing!

Just got home and on the drive saw a billboard that said “he who laughs last didn’t get the joke” Keep laughing regardless!

COVID-19 is no joke.

Re: Long Covid: major findings, mechanisms and recommendations

#197

Earlier quoted context omitted.

The boosters do almost nothing about XBB.1.5 and the upcoming strains - this is evolution at play! You can't use the same strategy we've used for the flu - this virus mutates much faster as it infects a lot more people.

My point was that we've reached the mid-term status quo. If you're still wearing a mask, you're going to be wearing it for a while.

I am fully aware of it and well used to it already - I've gone through hundreds of 3M and Moldex N95s already, I can properly put on and take off a face mask with a single hand in a second. I'm sure the first people who put on underwear were also ridiculed and others thought of them as crazies, but from modern day's perspective, they were the clever bunch.

Face masks might be a novelty in the Western Hemisphere, but in the more populated other half of our planet, people have been wearing masks as less inconvenient than getting sick.

People should learn about Hayflick limit before saying they can keep surviving a reinfection every couple of months - especially one, which exploits such a common receptor as ACE2!

Re: Long Covid: major findings, mechanisms and recommendations

#198
post #32

Earlier quoted context omitted.

I have had Covid at least 2 times and influenza once in the last 2 or 3 years. The influenza is the one that knocked me on my ass and sent me to the doctor thinking I might have something more wrong with me. Covid was meh, not worse than any other sickness the toddlers bring home.

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I'm willing to bet most people would pick a Covid reinfection over Influenza. That's not even minimising covid (although with such robust population immunity, now is the time to stop making such a unique deal about covid and to stop freaking out about every single variant) - it's simply that the flu is not a mild disease. Influenza is a horrible virus.

Re: Long Covid: major findings, mechanisms and recommendations

#199
post #143

Earlier quoted context omitted.

> 30% - 40% of the population disabled? That assumes likelihood of getting long covid doesn't drop after successive infections.

Some studies that infection actually may make it easier to catch it again https://www.science.org/doi/10.1126/science.abq1841 and that covid causes immunological dysfuction even 8 months later https://www.nature.com/articles/s41590-021-01113-x

Thanks for the links. The science study seems to be looking at the tipple vaccinated. There seems to be some indication, that this might influence the risk of reinfection as well.

https://www.medrxiv.org/content/10.1101/2022.12.17.22283625v...

See Figure 2 (end of the paper). Preprint, but pretty straightforward census of hospital staff.

Re: Long Covid: major findings, mechanisms and recommendations

#200

Earlier quoted context omitted.

> walk longer than a minute without needing to lay down for the rest of the day and sleep I'm sorry, do you mean it literally?

Not OP but yes, literally. A friend of mine has long covid, used to run marathons. For a time he was unable to go up the stairs without crashing hard.

I was asking beacause a friend of a friend has the similar condition after catastrophic motorbike crash. He spent a month on a medical bed and then had to learn walking again. During that, he had to rest a lot after a minute of walking. I can't believe that COVID can make the same near-death effect on a body.

Note: I had mild-to-serious COVID myself with severe fever and 12% of lungs damaged, and was literally one day from rushing to the hospital. 0/10 will not recommend, had to fight with after effects, but nothing even near what you or OP described.

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