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Long Covid: major findings, mechanisms and recommendations

nature.com

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Re: Long Covid: major findings, mechanisms and recommendations

#161

Post by anon84873628 »

godelski wrote: post #21
squidsoup wrote: post #12

Earlier quoted context omitted.

Significantly worse than the flu - multi systemic organ damage. The narrative that covid is like the flu, is both wildly inaccurate as this paper explains, and also dangerous, leading to a more cavalier attitude towards covid prevention.

Maybe I'm being generous to the parent, but I also would like a comparison to the flu. Not because I don't believe covid is significantly worse (when I got it, it was way worse than the flu), but because I don't have a medical background and it is difficult to contextualize the actual risks here without some baseline where I have a decent intuition already built around. But where I disagree with the parent is the nee…

It would be nice if someone explained the specific biological reason for why they are different. Like, because they target different types of cells, or reproduce in different ways.

The lay explanation of a virus is that it invades your cells and hijacks their machinery to make more of itself. That makes them all sound the same. For bacteria we at least can understand that they have different types of metabolism, come in different shapes, produce different defensive compounds, etc.

Re: Long Covid: major findings, mechanisms and recommendations

#162

Post by anon84873628 »

jasonhansel wrote: post #65
crims0n wrote: post #2

Interesting that they classify loss of smell as a neurological symptom. I had Covid last January and my sense of smell has never been the same. I used to be able to walk into a room, flair my nostrils, and pick up everything from the couch, carpet, and curtains… to the subtle cool drafts from the windows and fireplace. Now everything has completely dulled out, and I only occasionally pick up those old scents in passi…

I was confused by this, but I think they mean "neurological" as in "relating to the nervous system," specifically to the olfactory sensory neurons that detect smells.

At first you were probably thinking of the meaning of "psychological".

Part of the confusion probably comes from words like "neurosis" or "neurotic" which in fact fall under the discipline of psychiatry.

Re: Long Covid: major findings, mechanisms and recommendations

#163

Post by jandrewrogers »

seydor wrote: post #141
jandrewrogers wrote: post #116

Earlier quoted context omitted.

I’ve had COVID multiple times — I collect variants like Pokémon cards. The first one (pre-vaccine!) was nasty with a few lingering effects that went away after a month, the last was asymptomatic. In everyone I know that has had multiple infections — which is a lot of people these days — subsequent infections are much less consequential than the last, including lingering effects. This is what you would generally expec…

The studies tell the opposite. A large study in US veterans found increased risk in 2 and 3 times reinfected, including death https://www.reuters.com/business/healthcare-pharmaceuticals/... > Reinfected patients had a more than doubled risk of death and a more than tripled risk of hospitalization compared with those who were infected with COVID just once. They also had elevated risks for problems with lungs, heart, b…

The VA is almost nothing but old sick people, the demographic most susceptible to serious COVID. Fortunately, most of the population isn't old sick people. The study you reference isn't relevant to conversations about the general population.

The view that risk from subsequent infections is negligible is informed by the fact that vast numbers of people have had subsequent infections, including most of the people they know. Personal experience around this is widely discussed socially, so there is a broad consensus that their personal experience was normal and not an outlier. I live in progressive urban enclaves, so if these people are all misinformed then your cause is lost.

Constantly misrepresenting the science around COVID and fear-mongering over things that are manifestly not the case discredits the people that promote that, which runs the very real risk of causing people to dismiss the real risks of COVID. We already went down this road with climate change, where chronic gross misrepresentation of the science in popular media caused people to dismiss the actual and serious risks associated with climate change.

Disasturbation may be fun but it is a terrible way to convince the broader population that a category of risk needs to be taken seriously.

Re: Long Covid: major findings, mechanisms and recommendations

#164

Post by moistly »

parthianshotgun wrote: post #145
lossolo wrote: post #42

Earlier quoted context omitted.

> Additionally new research is uncovering serious and significant risks for the vaccine with fairly marginal protection benefits. Could you provide a link to that research ?

[flagged]

It’s a shame dang doesn’t nuke these disinformation agents from orbit.

Re: Long Covid: major findings, mechanisms and recommendations

#165

Post by nikolay »

galoisscobi wrote: post #159
nikolay wrote: post #107

COVID-19 is no joke. I know people want to move on with their lives, but people should stick to N95/KN-95/KF-94/FFP2/FFP3 masks for the time being unless we want to create a massive health care crisis and ruin the global economy as the if people get reinfected every few months, this would be imminent!

Strongly agree. It’s been frustrating to deal with this at work. I’m at a FAANG, and we’re required to come in 3 days a week. Coworkers came in visibly sick coughing away without wearing a mask. I wrote to people support and they say they can’t do anything about it, just recommend that I wear a mask and that’s about it.

Millions if not billions get sick every year, because sick people don't want to stay home. This irresponsible behavior should be regulated somehow otherwise people won't change!

Re: Long Covid: major findings, mechanisms and recommendations

#166

Post by WirelessGigabit »

I really hope they find something for the tinnitus that is COVID related. It's insane. I'm on friggin' hearing aids for it. 34y/o, always taken good care of my ears.

And then I got infected 4 months before I could get a vaccine. It's just not fair.

Re: Long Covid: major findings, mechanisms and recommendations

#167

Post by rybosworld »

alchemist1e9 wrote: post #85
rybosworld wrote: post #80

Earlier quoted context omitted.

> new research is uncovering serious and significant risks for the vaccine The frequency of the reaction mentioned in this article is around 2 in 100,000 people. The frequency of death from covid is somewhere in the range of 1000-2000 in 100,000 people. I'll take the vaccine odds. > with fairly marginal protection benefits Your source says nothing about protection benefits being marginal. In fact, one of the author's…

[flagged]

[flagged]

Re: Long Covid: major findings, mechanisms and recommendations

#168

Post by seydor »

jandrewrogers wrote: post #163
seydor wrote: post #141

Earlier quoted context omitted.

The studies tell the opposite. A large study in US veterans found increased risk in 2 and 3 times reinfected, including death https://www.reuters.com/business/healthcare-pharmaceuticals/... > Reinfected patients had a more than doubled risk of death and a more than tripled risk of hospitalization compared with those who were infected with COVID just once. They also had elevated risks for problems with lungs, heart, b…

The VA is almost nothing but old sick people, the demographic most susceptible to serious COVID. Fortunately, most of the population isn't old sick people. The study you reference isn't relevant to conversations about the general population. The view that risk from subsequent infections is negligible is informed by the fact that vast numbers of people have had subsequent infections , including most of the people they…

things cant be 'manifestly not the case' without evidence

Re: Long Covid: major findings, mechanisms and recommendations

#169

Post by [deleted] »

kuhewa wrote: post #89
jbritton wrote: post #70

Earlier quoted context omitted.

https://www.sciencedirect.com/science/article/pii/S0264410X2... https://jackanapes.substack.com/p/cdc-finally-released-its-v...

The study certainly doesn't support the claim of marginal benefits outweighing serious side effects.

[deleted]

Re: Long Covid: major findings, mechanisms and recommendations

#170

Post by threadweaver34 »

nikolay wrote: post #122
threadweaver34 wrote: post #111

Earlier quoted context omitted.

> people should stick to N95/KN-95/KF-94/FFP2/FFP3 masks for the time being Now that we have a vaccine and a bivalent booster, realize that you're suggesting masking for at least another 5 years. You said this, but it also has to be N95 at this point with how contagious it is. > people get reinfected every few months The realistic estimates are more like every year.

The boosters do almost nothing about XBB.1.5 and the upcoming strains - this is evolution at play! You can't use the same strategy we've used for the flu - this virus mutates much faster as it infects a lot more people.

My point was that we've reached the mid-term status quo. If you're still wearing a mask, you're going to be wearing it for a while.
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