Abstract: Running is a popular and convenient leisure-time physical activity (PA) with a significant impact on longevity. In general, runners have a 25%–40% reduced risk of premature mortality and live approximately 3 years longer than non-runners. Recently, specific questions have emerged regarding the extent of the health benefits of running versus other types of PA, and perhaps more critically, whether there are diminishing returns on health and mortality outcomes with higher amounts of running. This review details the findings surrounding the impact of running on various health outcomes and premature mortality, highlights plausible underlying mechanisms linking running with chronic disease prevention and longevity, identifies the estimated additional life expectancy among runners and other active individuals, and discusses whether there is adequate evidence to suggest that longevity benefits are attenuated with higher doses of running.
Conclusion: There is compelling evidence that running provides significant health benefits for the prevention of chronic diseases and premature mortality regardless of sex, age, body weight, and health conditions. There are strong plausible physiological mechanisms underlying how running can improve health and increase longevity. Running may be the most cost-effective lifestyle medicine from public health perspective, more important than other lifestyle and health risk factors such as smoking, obesity, HTN, and DM. It is not clear, however, how much running is safe and efficacious and whether it is possible to perform an excessive amount of exercise. Also, running may have the most public health benefits, but is not the best exercise for everyone since orthopedic or other medical conditions can restrict its use by many individuals.
http://www.sciencedirect.com/science/article/pii/S0033062017...
NYT reporting on the study ("An Hour of Running May Add 7 Hours to Your Life"):
https://www.nytimes.com/2017/04/12/well/move/an-hour-of-runn...