GLP-1 drugs linked to lower death rates in colon cancer patients

Post by trallnag » Thu, Nov 13, 2025, 1:15 PM UTC

amenhotep wrote: post #106

trallnag wrote: post #94

Earlier quoted context omitted.

Awesome insight. It's not the disability I have, it's that I have never tried healing by fasting. Of course. Because my body was always busy trying to eat food instead of fixing and regrowing all the malformed tissue. Because that's how it works. When a person without legs starts to fast, the legs will suddenly develop.

It would be sensible for you to examine and interrogate why reading a general and fairly anodyne opinion about what might be a solution to a problem some people have led you to interpret it as a prescriptive and judgemental suggestion about the specific problem you specifically have.

Post by codr7 » Thu, Nov 13, 2025, 1:42 PM UTC

cyrusradfar wrote: post #81

jl6 wrote: post #22

> However, the study authors emphasize that more research is needed to confirm these mechanisms and determine whether the survival benefit observed in this real-world analysis represents a direct anti-cancer effect or an indirect result of improved metabolic health Given it’s an observational study, I would bet on the latter. It’s really hard to know you’ve controlled for all confounding factors, and there’s a strong…

Agreed. I'm a big fan of intermittent and water fasting. Have seen things in my blood work that doctors would require me on meds to reverse. Outside of that, I can't speak to the positive impacts on my mood, and general ability to focus. The simplest solution to a lot of problems is consuming less with the assumption that, most of us (maybe not you), have a lot of spare energy sitting around. A lie that we don't unle…

Post by codr7 » Thu, Nov 13, 2025, 1:48 PM UTC

Cthulhu_ wrote: post #128

cyrusradfar wrote: post #81

Earlier quoted context omitted.

Agreed. I'm a big fan of intermittent and water fasting. Have seen things in my blood work that doctors would require me on meds to reverse. Outside of that, I can't speak to the positive impacts on my mood, and general ability to focus. The simplest solution to a lot of problems is consuming less with the assumption that, most of us (maybe not you), have a lot of spare energy sitting around. A lie that we don't unle…

I for one don't "require" three meals a day, but I'm hungry in the morning, ergo, I like breakfast. It's not so much about how often you eat but what and how much. Generally speaking, of course, I can't speak for any benefits of intermittent fasting (assuming equal daily calorie / macronutrient intake) because I'm uneducated in that regard. But TL;DR, I will agree that desk jockeys will need less calories than people…

Post by basisword » Thu, Nov 13, 2025, 2:00 PM UTC

foobarian wrote: post #151

donsupreme wrote: post #88

Earlier quoted context omitted.

I hypothesize that the appetite-suppressing effect of GLP-1 agonists contributes to the normalization of dopamine signaling in the brain. By mitigating the exaggerated dopamine fluctuations seen in food and sugar addiction, GLP-1 may promote a return to dopamine homeostasis, thereby reducing compulsive or addiction-like reward-seeking behaviors.

Wonder if it would help compulsive gamblers then.

Post by toomuchtodo » Thu, Nov 13, 2025, 2:15 PM UTC

culi wrote: post #104

toomuchtodo wrote: post #40

Earlier quoted context omitted.

Many Americans drive a car every day, even though ~40k people a year die in car accidents. Why? Because the benefits outweigh the risk. (my partner is on a GLP-1, and lost ~25 lbs in 3 months)

> Why? Because the benefits outweigh the risk Many of us wish we didn't have to drive a car. Many of us also wish we didn't live in a world where hyperprocessed foods weren't the norm