Earlier quoted context omitted.
OTOH acetaminophen is known to be toxic; is there an alternative here for non narcotic inflammation, fever, and pain relief that is shown NOT to have tradeoffs for use?
Kratom / Cannabis oh wait these are illegal so big pharma can milk their poisons.
Ibuprofen alters human testicular physiology to produce compensated hypogonadism
151–160 of 251 posts
Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism
#152Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism
#153So back to good old aspirin? Acetaminophen slowly kills your liver and Ibuprofen messes with testosterone production.
It is only when you attempt to overdose (or if you have severely limited liver function) that you run out of the liver enzymes that break it down, causing liver damage.
Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism
#154Earlier quoted context omitted.
OTOH acetaminophen is known to be toxic; is there an alternative here for non narcotic inflammation, fever, and pain relief that is shown NOT to have tradeoffs for use?
Kratom / Cannabis oh wait these are illegal so big pharma can milk their poisons.
Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism
#155Earlier quoted context omitted.
OTOH acetaminophen is known to be toxic; is there an alternative here for non narcotic inflammation, fever, and pain relief that is shown NOT to have tradeoffs for use?
Kratom / Cannabis oh wait these are illegal so big pharma can milk their poisons.
I honestly think the obstacle to Cannabis legalization in the US is social conservatism, not industrial lobbying.
Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism
#156"Ibuprofen and hypogonadism — bench to bedside to misinterpreted hype?" at https://www.nature.com/articles/nrurol.2018.26 : > A recent study suggests modulation of luteinizing hormone signalling within the hypothalamic–pituitary–gonadal axis and downstream transcriptional effects caused by sustained ibuprofen use. However, this study cannot be used to draw any clinical conclusions regarding effects of ibuprofen on ma…
Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism
#157Earlier quoted context omitted.
Ibuprofen is anti-inflammatory medication.
>Ibuprofen is anti-inflammatory medication. And an acetaminophen tablet is a painkiller. While your statement is in fact true, ibuprofen is still a better choice for a fever. The latter is also generally considered a safer alternative, especially in long-term use — even though alternating the two would be ideal.
On top of that numerous recent studies have shown many potential problems.
https://www.webmd.com/drug-medication/news/20150302/does-lon...
> Heavy use of acetaminophen is associated with kidney disease and bleeding in the digestive tract, the paper reports. The medication also has been linked to increased risk of heart attack, stroke and high blood pressure, the study authors noted.
> One cited study even showed that overuse of acetaminophen can increase a person's risk of early death as much as 60 percent, the study authors found.
Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism
#158"Ibuprofen and hypogonadism — bench to bedside to misinterpreted hype?" at https://www.nature.com/articles/nrurol.2018.26 : > A recent study suggests modulation of luteinizing hormone signalling within the hypothalamic–pituitary–gonadal axis and downstream transcriptional effects caused by sustained ibuprofen use. However, this study cannot be used to draw any clinical conclusions regarding effects of ibuprofen on ma…
Sounds like the industry responding with "we cant really know guys, right?" I'm throwing away my Advil right now. Screw that.
Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism
#159Earlier quoted context omitted.
This. Just had friends visiting. Their teenage son had had his wisdom tooth pulled last week. Dentist had then given him (as a standard practice?) prescription for Ibuprofen (800mg tabs?) AND some opioid based pain killer! Needless to say, latter they said went directly to trash after they realized what it contained and for ibuprofen they halved the dosage. To me and his parents this was pain management gone way over…
I just had wisdom teeth extraction a few weeks back. I was given 800mg Ibuprofen and Norco. The pain was bad enough to wake me up at night when the meds wore off — and I did take both. Oral surgery is no joke. It took me about 8 days to taper to 400mg Ibuprofen. These doctors don’t just give pills out randomly, they do it for a reason based on evidence and science. A side note is that my pharmacist made it very clear…
IMHO the doctors should prescribe less at first and see if it would be enough, but I also get that they are overcrowded and the same patient coming back for just more painkillers might be a little too much.
Re: Ibuprofen alters human testicular physiology to produce compensated hypogonadism
#160This is terrifying. I used to take a lot of ibuprofen for frequent headaches (much better now). Military doctors were overzealous with the 800mg prescriptions (double the OTC dose). I suppose I should just use naproxen or acetaminophen? Ibuprofen always seemed the most effective to me.