Anti-aging injection regrows knee cartilage and prevents arthritis • Hacker News Board

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#141

Post by snowwrestler » Mon, Jan 05, 2026, 12:53 PM UTC

usrme wrote: post #110

belZaah wrote: post #106

Earlier quoted context omitted.

Trail running is fun. But it’s probably not the surface but the technique change, that gets rid of the pain. I’m currently going through the process of shifting my running technique to where I push rather than pull myself forward and it’s a revelation. When your foot lands in front of your center of gravity, it necessarily brakes your forward movement. All that momentum has to go somewhere, eg get absorbed by your jo…

This sounds interesting. Would you be able to share more information about this style of running? I'm having a hard time imagining how this plays out in real life.

I made this change as well. Specifically, I switched from heel strike to forefoot strike, AKA “landing on the ball of my foot.” I changed shoes to zero-drop (Altras) which makes this easier to do.

This sort of automatically limits how far in front of your hips you can land your foot. But then the next step is to change posture and “lean forward” so that it feels like you’re just barely catching yourself with each foot before falling on your face.

The goal is to have your foot land directly under you, then use your quads and glutes to push your foot backward, to create or maintain your forward momentum.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#142

Post by btylke » Mon, Jan 05, 2026, 1:02 PM UTC

kelipso wrote: post #68

IsTom wrote: post #64

Earlier quoted context omitted.

Still, if you eat enough complete protein sources you'll have all the amino acids you need.

Maybe, maybe not. It would depend on a variety of factors including the activities you do, your age, etc. Maybe athletes need more collagen compared to people who don’t exercise, etc, etc. Also complete protein sources are definitely not easy to get. Good luck if you have dietary constraints.

Quinoa is a complete protein, containing all amino acids that the body cannot produce on its own, and is gluten free.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#143

Post by snowwrestler » Mon, Jan 05, 2026, 1:03 PM UTC

mancerayder wrote: post #78

mcswell wrote: post #73

Anecdote for any runners reading this: I'm a 75 year old runner. (Some young runners might say I run at a jogger's pace, I just tell them to keep off my lawn.) A couple decades ago, I stopped running on concrete or asphalt, and took up trail running, i.e. running on (mostly) dirt. It feels way easier than running on asphalt, much less on concrete. If you're skeptical that running on concrete or asphalt feels harder,…

I'd worry about sprained ankles on a false step or a slippery leaf-rock trap. Is there a technical approach to running in these conditions?

For me the biggest insight was that there is no rule I have to be “running” 100% of the time when trail running. If some part of the trail seems sketchy it’s totally fine to just slow down there and do that part carefully. Then speed up to running again on safer parts.

You’re still getting almost all of the cardio benefits, and over time you’ll get more comfortable going faster on different surfaces, just from practice.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#144

Post by lostlogin » Mon, Jan 05, 2026, 1:41 PM UTC

prmoustache wrote: post #128

lostlogin wrote: post #116

Earlier quoted context omitted.

A poorly adjusted cleat is absolute hell on the knee. It can be difficult to fix too as once your knee is sore it takes ages to come right so it’s not clear if adjusting the cleat is working.

Most people don't need clipless pedals and only do that to mimick pros or because they were told to by other cyclists. This is stupid (saying that as an ex elite road, track and cyclocross racer).

Maybe not, do what suits but I find it helps, particularly over longer distances or up hills.

I’ve never tried real cleats, I just use mounting biking ones, spd. Doubled sided pedals seem easier in traffic and I use them for a decidedly non-pro 2-300km a week.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#145

Post by jMyles » Mon, Jan 05, 2026, 1:44 PM UTC

circlefavshape wrote: post #122

jMyles wrote: post #12

Earlier quoted context omitted.

> The joint at the base of my thumb started telling me it's 60 years old This is my biggest apprehension. I've become quite a good guitarist, and I know that can't last forever. Getting my accomplishments in while I can.

Your accomplishments? For me playing music is for joy, not for status

My first bluegrass record:

https://justinholmes.bandcamp.com/album/vowel-sounds

Second record in progress:

https://justinholmes.bandcamp.com/album/4masks

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#146

Post by yep31 » Mon, Jan 05, 2026, 2:05 PM UTC

8f2ab37a-ed6c wrote: post #98

yep31 wrote: post #83

Earlier quoted context omitted.

You should try 20g springs, they are really good for typing. I also removed the keycaps and replaced them with small pieces of band-aid on top of the switch stems which also helped. Also dictating plain text like comments and typing only for correcting errors in dictation and for short actions is better. It's easier to press a button rather than say a lengthy command, because vocal cords can also be damaged by speaki…

Where have you been able to find ultralight springs available to consumers? I was looking into this last week and the 10-20g ones were only available straight from the factory in South Korea with shipping costing $200... I was happy to get them and swap them out, but that shipping pricetag was too much of a highway robbery. Would appreciate any advice here :) And, intrigued about the idea of not using key switches at…

[dead]

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#147

Post by [deleted] » Mon, Jan 05, 2026, 2:31 PM UTC

circlefavshape wrote: post #122

jMyles wrote: post #12

Earlier quoted context omitted.

> The joint at the base of my thumb started telling me it's 60 years old This is my biggest apprehension. I've become quite a good guitarist, and I know that can't last forever. Getting my accomplishments in while I can.

Your accomplishments? For me playing music is for joy, not for status

[deleted]

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#148

Post by yep32 » Mon, Jan 05, 2026, 3:05 PM UTC

8f2ab37a-ed6c wrote: post #98

yep31 wrote: post #83

Earlier quoted context omitted.

You should try 20g springs, they are really good for typing. I also removed the keycaps and replaced them with small pieces of band-aid on top of the switch stems which also helped. Also dictating plain text like comments and typing only for correcting errors in dictation and for short actions is better. It's easier to press a button rather than say a lengthy command, because vocal cords can also be damaged by speaki…

Where have you been able to find ultralight springs available to consumers? I was looking into this last week and the 10-20g ones were only available straight from the factory in South Korea with shipping costing $200... I was happy to get them and swap them out, but that shipping pricetag was too much of a highway robbery. Would appreciate any advice here :) And, intrigued about the idea of not using key switches at…

Here is an interesting discussion about low-weight springs old.reddit.com/r/MechanicalKeyboards/comments/ojk0em/experiences\_with\_very\_low\_weight\_8\_to\_25g\_spring/. It has a link to rndkbd.com /products /sprit-springs?variant=43822770782442, where I purchased my springs. They have a full range starting from 12g, but they are currently out of stock. You can ask about the next restock on their Discord server.

One thing I discovered about lightweight springs is that lubing the switch doesn't work at all, it just stops resetting. I also think that with traditional MX-style switches going with weight less than 20g might not work out well because even with 20g springs some of my keys are not resetting properly, they remain stuck when I lift my finger, and I get "aaaaaaaaaaaaaaaa"s instead of just "a" for example.

As for removing keycaps, my keyboard looks like this: m.youtube.com/watch?v=647FeK3\_Bek, except I left the spacebar keycap on, and I have a small piece of adhesive plaster tape on top of the plastic parts that resembles a plus sign "+" on every switch to increase friction. But I don't think removing keycaps works for switches box type switches with stems that look like [+]. I also had to open the space bar switch and add a little aluminum foil ring inside where the spring is located because it consistently wouldn’t reset.

Lightweight springs also slightly reduce the key travel distance, and the actuation point becomes very high, practically no actuation point. It produces a keystroke the moment you touch it. This is now possible with harder springs too with the advent of Hall effect keyboards, but the lightest spring available for that type of keyboard is 28g, which is a bit too heavy.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#149

Post by linsomniac » Mon, Jan 05, 2026, 3:14 PM UTC

callamdelaney wrote: post #124

linsomniac wrote: post #27

I have had fairly serious arthritis in my hips for close to a decade now. Cortizone shots directly into the joint have helped the worst of the flare-ups (limping on my way into the shot, having 0 pain walking out of it, lasting a year). 5+ years ago when I was looking for another injection, my PCP said "Well, time for a hip replacement." Now, for reasons I don't understand I think he was being way premature on that (…

Hey, could I ask which stretch it was?

Look for the reply with "Frog Mobility" in the body, I posted in reply to another comment.

Re: Anti-aging injection regrows knee cartilage and prevents arthritis

#150

Post by ca_tech » Mon, Jan 05, 2026, 3:26 PM UTC

belZaah wrote: post #106

mcswell wrote: post #73

Anecdote for any runners reading this: I'm a 75 year old runner. (Some young runners might say I run at a jogger's pace, I just tell them to keep off my lawn.) A couple decades ago, I stopped running on concrete or asphalt, and took up trail running, i.e. running on (mostly) dirt. It feels way easier than running on asphalt, much less on concrete. If you're skeptical that running on concrete or asphalt feels harder,…

Trail running is fun. But it’s probably not the surface but the technique change, that gets rid of the pain. I’m currently going through the process of shifting my running technique to where I push rather than pull myself forward and it’s a revelation. When your foot lands in front of your center of gravity, it necessarily brakes your forward movement. All that momentum has to go somewhere, eg get absorbed by your jo…

This is why I think trail running is so valuable. You must be aware of your changing environment and how to adjust your body's movement to accommodate. You are exercising your mind to calculate your current momentum, intended placement of your next step, and it's potential impact to the rest of your body. You are running your own mental physics simulation as you work the trail, nothing like running on regular roads.